Bromoenol lactone promotes cell death by a mechanism involving phosphatidate phosphohydrolase-1 rather than calcium-independent phospholipase A2 L Fuentes, R Pérez, ML Nieto, J Balsinde, MA Balboa Journal of Biological Chemistry 278 (45), 44683-44690, 2003 | 205 | 2003 |
Secretory phospholipase A2 activates the cascade of mitogen-activated protein kinases and cytosolic phospholipase A2 in the human astrocytoma cell line 1321N1 M Hernández, SL Burillo, MS Crespo, ML Nieto Journal of Biological Chemistry 273 (1), 606-612, 1998 | 190 | 1998 |
Acidic triterpenes compromise growth and survival of astrocytoma cell lines by regulating reactive oxygen species accumulation R Martin, J Carvalho, E Ibeas, M Hernández, V Ruiz-Gutierrez, ML Nieto Cancer research 67 (8), 3741-3751, 2007 | 154 | 2007 |
Characteristics of the binding of platelet-activating factor to platelets of different animal species P Inarrea, J Gomez-Cambronero, M Nieto, MS Crespo European journal of pharmacology 105 (3-4), 309-315, 1984 | 149 | 1984 |
Evidence that hydrolysis of ethanolamine plasmalogens triggers synthesis of platelet-activating factor via a transacylation reaction. ML Nieto, ME Venable, SA Bauldry, DG Greene, M Kennedy, DA Bass, ... Journal of Biological Chemistry 266 (28), 18699-18706, 1991 | 130 | 1991 |
Beneficial actions of oleanolic acid in an experimental model of multiple sclerosis: a potential therapeutic role R Martín, J Carvalho-Tavares, M Hernández, M Arnes, V Ruiz-Gutierrez, ... Biochemical pharmacology 79 (2), 198-208, 2010 | 129 | 2010 |
Occupancy of platelet receptors for platelet-activating factor in patients with septicemia. FL Diez, ML Nieto, S Fernandez-Gallardo, MA Gijon, MS Crespo The Journal of clinical investigation 83 (5), 1733-1740, 1989 | 127 | 1989 |
Signaling mechanisms involved in the activation of arachidonic acid metabolism in human astrocytoma cells by tumor necrosis factor‐α: phosphorylation of cytosolic phospholipase … M Hernández, Y Bayón, MS Crespo, ML Nieto Journal of neurochemistry 73 (4), 1641-1649, 1999 | 87 | 1999 |
Natural triterpenic diols promote apoptosis in astrocytoma cells through ROS-mediated mitochondrial depolarization and JNK activation R Martín, E Ibeas, J Carvalho-Tavares, M Hernández, V Ruiz-Gutierrez, ... PLoS One 4 (6), e5975, 2009 | 83 | 2009 |
Natural triterpenes modulate immune‐inflammatory markers of experimental autoimmune encephalomyelitis: Therapeutic implications for multiple sclerosis R Martín, M Hernández, C Cordova, ML Nieto British Journal of Pharmacology 166 (5), 1708-1723, 2012 | 82 | 2012 |
Conversion of 1-O-[3H] alkyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine to lyso platelet-activating factor by the CoA-independent transacylase in membrane fractions of human … ME Venable, ML Nieto, JD Schmitt, RL Wykle Journal of Biological Chemistry 266 (28), 18691-18698, 1991 | 78 | 1991 |
Inhibition of the vascular actions of IgG aggregates by BN 52021, a highly specific antagonist of PAF-acether M Sánchez-Crespo, S Fernández-Gallardo, ML Nieto, J Baranès, ... Immunopharmacology 10 (2), 69-75, 1985 | 77 | 1985 |
Modulation of acetyl-CoA: 1-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PAF) acetyltransferase in human polymorphonuclears. The role of cyclic AMP-dependent and phospholipid … ML Nieto, S Velasco, MS Crespo Journal of Biological Chemistry 263 (10), 4607-4611, 1988 | 76 | 1988 |
Biological effects of group IIA secreted phosholipase A (2) L Fuentes, M Hernandez, ML Nieto, M Sanchez Crespo FEBS Lett. 531, 7–11, 2002 | 75 | 2002 |
Oleanolic acid modulates the immune-inflammatory response in mice with experimental autoimmune myocarditis and protects from cardiac injury. Therapeutic implications for the … R Martín, C Cordova, JA San Román, B Gutierrez, V Cachofeiro, ML Nieto Journal of Molecular and Cellular Cardiology 72, 250-262, 2014 | 73 | 2014 |
Cytosolic phospholipase A2 is coupled to muscarinic receptors in the human astrocytoma cell line 1321N1: characterization of the transducing mechanism Y Bayón, M Hernández, A Alonso, L Núñez, J García-Sancho, C LESLIE, ... Biochemical Journal 323 (1), 281-287, 1997 | 69 | 1997 |
Secreted phospholipase A2 type IIA as a mediator connecting innate and adaptive immunity: new role in atherosclerosis E Ibeas, L Fuentes, R Martín, M Hernández, ML Nieto Cardiovascular research 1, 54-63., 2009 | 63 | 2009 |
Lipopolysaccharides of Brucella abortusand Brucella melitensis Induce Nitric Oxide Synthesis in Rat Peritoneal Macrophages L López-Urrutia, A Alonso, ML Nieto, Y Bayón, A Orduña, ... Infection and immunity 68 (3), 1740-1745, 2000 | 61 | 2000 |
Cooperation Between Secretory Phospholipase A2 and TNF-Receptor Superfamily Signaling: Implications for the Inflammatory Response in Atherogenesis L Fuentes, M Hernández, FJ Fernández-Avilés, MS Crespo, ML Nieto Circulation research 91 (8), 681-688, 2002 | 56 | 2002 |
Secreted PLA2 induces proliferation in astrocytoma through the EGF receptor: another inflammation-cancer link M Hernandez, R Martín, MD García-Cubillas, P Maeso-Hernandez, ... Neuro-oncology 12 (10), 1014-1023, 2010 | 55 | 2010 |