A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion–resistant growth Z Guo, X Yang, F Sun, R Jiang, DE Linn, H Chen, H Chen, X Kong, ... Cancer research 69 (6), 2305-2313, 2009 | 1091 | 2009 |
The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism C Sebastián, BMM Zwaans, DM Silberman, M Gymrek, A Goren, L Zhong, ... Cell 151 (6), 1185-1199, 2012 | 701 | 2012 |
Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer R Hu, C Lu, EA Mostaghel, S Yegnasubramanian, M Gurel, C Tannahill, ... Cancer research 72 (14), 3457-3462, 2012 | 654 | 2012 |
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer SA Eccles, EO Aboagye, S Ali, AS Anderson, J Armes, F Berditchevski, ... Breast Cancer Research 15, 1-37, 2013 | 504 | 2013 |
Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana K Mayer, C Schüller, R Wambutt, G Murphy, G Volckaert, T Pohl, ... Nature 402 (6763), 769-777, 1999 | 487 | 1999 |
Androgen receptor gene amplification and protein expression in hormone refractory prostate cancer J Edwards, NS Krishna, KM Grigor, JMS Bartlett British journal of cancer 89 (3), 552-556, 2003 | 477 | 2003 |
Mannose impairs tumour growth and enhances chemotherapy PS Gonzalez, J O’Prey, S Cardaci, VJA Barthet, J Sakamaki, F Beaumatin, ... Nature 563 (7733), 719-723, 2018 | 355 | 2018 |
Post-anaesthesia pulmonary complications after use of muscle relaxants (POPULAR): a multicentre, prospective observational study E Kirmeier, LI Eriksson, H Lewald, MJ Fagerlund, A Hoeft, M Hollmann, ... The Lancet Respiratory Medicine 7 (2), 129-140, 2019 | 307 | 2019 |
Successful treatment of primary amebic meningoencephalitis JS Seidel, P Harmatz, GS Visvesvara, A Cohen, J Edwards, J Turner New England Journal of Medicine 306 (6), 346-348, 1982 | 279 | 1982 |
Observer variation in immunohistochemical analysis of protein expression, time for a change? T Kirkegaard, J Edwards, S Tovey, LM McGlynn, SN Krishna, ... Histopathology 48 (7), 787-794, 2006 | 265 | 2006 |
Gene amplifications associated with the development of hormone-resistant prostate cancer J Edwards, NS Krishna, CJ Witton, JMS Bartlett Clinical cancer research 9 (14), 5271-5281, 2003 | 259 | 2003 |
Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study J Glasbey, A Ademuyiwa, A Adisa, E AlAmeer, AP Arnaud, F Ayasra, ... The Lancet Oncology 22 (11), 1507-1517, 2021 | 248 | 2021 |
NF-κB pathways in the development and progression of colorectal cancer M Patel, PG Horgan, DC McMillan, J Edwards Translational Research 197, 43-56, 2018 | 219 | 2018 |
Expression levels of the JAK/STAT pathway in the transition from hormone-sensitive to hormone-refractory prostate cancer L Tam, LM McGlynn, P Traynor, R Mukherjee, JMS Bartlett, J Edwards British journal of cancer 97 (3), 378-383, 2007 | 204 | 2007 |
High expression of sphingosine 1-phosphate receptors, S1P1 and S1P3, sphingosine kinase 1, and extracellular signal-regulated kinase-1/2 is associated with development of … C Watson, JS Long, C Orange, CL Tannahill, E Mallon, LM McGlynn, ... The American journal of pathology 177 (5), 2205-2215, 2010 | 198 | 2010 |
MCL-1 is a prognostic indicator and drug target in breast cancer KJ Campbell, S Dhayade, N Ferrari, AH Sims, E Johnson, SM Mason, ... Cell death & disease 9 (2), 19, 2018 | 181 | 2018 |
The relationship between components of tumour inflammatory cell infiltrate and clinicopathological factors and survival in patients with primary operable invasive ductal breast … Z Mohammed, JJ Going, J Edwards, B Elsberger, JC Doughty, ... British journal of cancer 107 (5), 864-873, 2012 | 180 | 2012 |
Is PTEN loss associated with clinical outcome measures in human prostate cancer? P McCall, CJ Witton, S Grimsley, KV Nielsen, J Edwards British journal of cancer 99 (8), 1296-1301, 2008 | 179 | 2008 |
The androgen receptor and signal-transduction pathways in hormone-refractory prostate cancer. Part 2: Androgen-receptor cofactors and bypass pathways J Edwards, JMS Bartlett BJU international 95 (9), 1327-1335, 2005 | 178 | 2005 |
SRC family kinase activity is up-regulated in hormone-refractory prostate cancer O Tatarov, TJ Mitchell, M Seywright, HY Leung, VG Brunton, J Edwards Clinical Cancer Research 15 (10), 3540-3549, 2009 | 172 | 2009 |