Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells ML Hegde, TK Hazra, S Mitra Cell research 18 (1), 27-47, 2008 | 835 | 2008 |
Aluminium in Alzheimer’s disease: are we still at a crossroad? VB Gupta, S Anitha, ML Hegde, L Zecca, RM Garruto, R Ravid, ... Cellular and Molecular Life Sciences CMLS 62, 143-158, 2005 | 436 | 2005 |
Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects J Mitra, EN Guerrero, PM Hegde, NF Liachko, H Wang, V Vasquez, J Gao, ... Proceedings of the National Academy of Sciences 116 (10), 4696-4705, 2019 | 252 | 2019 |
Oxidized guanine base lesions function in 8-oxoguanine DNA glycosylase-1-mediated epigenetic regulation of nuclear factor κB-driven gene expression L Pan, B Zhu, W Hao, X Zeng, SA Vlahopoulos, TK Hazra, ML Hegde, ... Journal of Biological Chemistry 291 (49), 25553-25566, 2016 | 193 | 2016 |
Challenges associated with metal chelation therapy in Alzheimer's disease ML Hegde, P Bharathi, A Suram, C Venugopal, R Jagannathan, P Poddar, ... Journal of Alzheimer's Disease 17 (3), 457-468, 2009 | 177 | 2009 |
Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Sclerosis H Wang, W Guo, J Mitra, PM Hegde, T Vandoorne, BJ Eckelmann, S Mitra, ... Nature Communications 9 (1), 3683, 2018 | 170 | 2018 |
Oxidative genome damage and its repair: implications in aging and neurodegenerative diseases ML Hegde, AK Mantha, TK Hazra, KK Bhakat, S Mitra, B Szczesny Mechanisms of ageing and development 133 (4), 157-168, 2012 | 170 | 2012 |
Preferential repair of oxidized base damage in the transcribed genes of mammalian cells D Banerjee, SM Mandal, A Das, ML Hegde, S Das, KK Bhakat, I Boldogh, ... Journal of Biological Chemistry 286 (8), 6006-6016, 2011 | 168 | 2011 |
Serum trace element levels and the complexity of inter-element relations in patients with Parkinson's disease ML Hegde, P Shanmugavelu, B Vengamma, TSS Rao, RB Menon, ... Journal of Trace Elements in Medicine and Biology 18 (2), 163-171, 2004 | 162 | 2004 |
Interaction of the human DNA glycosylase NEIL1 with proliferating cell nuclear antigen: the potential for replication-associated repair of oxidized bases in mammalian genomes H Dou, CA Theriot, A Das, ML Hegde, Y Matsumoto, I Boldogh, TK Hazra, ... Journal of Biological Chemistry 283 (6), 3130-3140, 2008 | 152 | 2008 |
Activation of ras signaling pathway by 8-oxoguanine DNA glycosylase bound to its excision product, 8-oxoguanine I Boldogh, G Hajas, L Aguilera-Aguirre, ML Hegde, Z Radak, A Bacsi, ... Journal of Biological Chemistry 287 (25), 20769-20773, 2012 | 145 | 2012 |
The role of 8-oxoguanine DNA glycosylase-1 in inflammation X Ba, L Aguilera-Aguirre, QTAN Rashid, A Bacsi, Z Radak, S Sur, ... International journal of molecular sciences 15 (9), 16975-16997, 2014 | 135 | 2014 |
TDP-43/FUS in motor neuron disease: Complexity and challenges EN Guerrero, H Wang, J Mitra, PM Hegde, SE Stowell, NF Liachko, ... Progress in neurobiology 145, 78-97, 2016 | 132 | 2016 |
Recent advances in α-synuclein functions, advanced glycation, and toxicity: implications for Parkinson’s disease E Guerrero, P Vasudevaraju, ML Hegde, GB Britton, KS Rao Molecular neurobiology 47, 525-536, 2013 | 129 | 2013 |
The human Werner syndrome protein stimulates repair of oxidative DNA base damage by the DNA glycosylase NEIL1 A Das, I Boldogh, JW Lee, JA Harrigan, ML Hegde, J Piotrowski, ... Journal of Biological Chemistry 282 (36), 26591-26602, 2007 | 124 | 2007 |
Prereplicative repair of oxidized bases in the human genome is mediated by NEIL1 DNA glycosylase together with replication proteins ML Hegde, PM Hegde, LJ Bellot, SM Mandal, TK Hazra, GM Li, I Boldogh, ... Proceedings of the National Academy of Sciences 110 (33), E3090-E3099, 2013 | 123 | 2013 |
The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3’-phosphatase in spinocerebellar ataxia type 3 pathogenesis A Chatterjee, S Saha, A Chakraborty, A Silva-Fernandes, SM Mandal, ... PLoS genetics 11 (1), e1004749, 2015 | 120 | 2015 |
Revisiting the intersection of amyloid, pathologically modified tau and iron in Alzheimer’s disease from a ferroptosis perspective PJ Derry, ML Hegde, GR Jackson, R Kayed, JM Tour, AL Tsai, TA Kent Progress in neurobiology 184, 101716, 2020 | 116 | 2020 |
Physical and functional interaction between human oxidized base-specific DNA glycosylase NEIL1 and flap endonuclease 1 ML Hegde, CA Theriot, A Das, PM Hegde, Z Guo, RK Gary, TK Hazra, ... Journal of Biological Chemistry 283 (40), 27028-27037, 2008 | 111 | 2008 |
Polyphenols as potential metal chelation compounds against Alzheimer’s disease J Lakey-Beitia, AM Burillo, G La Penna, ML Hegde, KS Rao Journal of Alzheimer's Disease 82 (s1), S335-S357, 2021 | 107 | 2021 |