IL-10 alters immunoproteostasis in APP mice, increasing plaque burden and worsening cognitive behavior P Chakrabarty, A Li, C Ceballos-Diaz, JA Eddy, CC Funk, B Moore, ... Neuron 85 (3), 519-533, 2015 | 388 | 2015 |
Substrate-targeting γ-secretase modulators TL Kukar, TB Ladd, MA Bann, PC Fraering, R Narlawar, GM Maharvi, ... Nature 453 (7197), 925-929, 2008 | 378 | 2008 |
Amyloid-β (1− 42) rapidly forms protofibrils and oligomers by distinct pathways in low concentrations of sodium dodecylsulfate V Rangachari, BD Moore, DK Reed, LK Sonoda, AW Bridges, E Conboy, ... Biochemistry 46 (43), 12451-12462, 2007 | 212 | 2007 |
Divergent effects of the H50Q and G51D SNCA mutations on the aggregation of α‐synuclein NJ Rutherford, BD Moore, TE Golde, BI Giasson Journal of neurochemistry 131 (6), 859-867, 2014 | 145 | 2014 |
BRI2 (ITM2b) inhibits Aβ deposition in vivo J Kim, VM Miller, Y Levites, KJ West, CW Zwizinski, BD Moore, ... Journal of Neuroscience 28 (23), 6030-6036, 2008 | 143 | 2008 |
Overlapping profiles of Aβ peptides in the Alzheimer's disease and pathological aging brains BD Moore, P Chakrabarty, Y Levites, TL Kukar, AM Baine, T Moroni, ... Alzheimer's research & therapy 4, 1-15, 2012 | 130 | 2012 |
Secondary structure and interfacial aggregation of amyloid-β (1− 40) on sodium dodecyl sulfate micelles V Rangachari, DK Reed, BD Moore, TL Rosenberry Biochemistry 45 (28), 8639-8648, 2006 | 112 | 2006 |
Organotypic brain slice cultures to model neurodegenerative proteinopathies CL Croft, HS Futch, BD Moore, TE Golde Molecular Neurodegeneration 14, 1-11, 2019 | 108 | 2019 |
Lysine 624 of the amyloid precursor protein (APP) is a critical determinant of amyloid β peptide length: support for a sequential model of γ-secretase intramembrane proteolysis … TL Kukar, TB Ladd, P Robertson, SA Pintchovski, B Moore, MA Bann, ... Journal of Biological Chemistry 286 (46), 39804-39812, 2011 | 82 | 2011 |
Short Aβ peptides attenuate Aβ42 toxicity in vivo BD Moore, J Martin, L De Mena, J Sanchez, PE Cruz, C Ceballos-Diaz, ... Journal of Experimental Medicine 215 (1), 283-301, 2018 | 79 | 2018 |
Biophysical analyses of synthetic Amyloid-β (1− 42) aggregates before and after covalent cross-linking. Implications for deducing the structure of endogenous Amyloid-β oligomers BD Moore, V Rangachari, WM Tay, NM Milkovic, TL Rosenberry Biochemistry 48 (49), 11796-11806, 2009 | 66 | 2009 |
TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer’s disease P Chakrabarty, A Li, TB Ladd, MR Strickland, EJ Koller, JD Burgess, ... Journal of Experimental Medicine 215 (9), 2247-2264, 2018 | 59 | 2018 |
Reversible pathologic and cognitive phenotypes in an inducible model of Alzheimer-amyloidosis T Melnikova, S Fromholt, HS Kim, D Lee, G Xu, A Price, BD Moore, ... Journal of Neuroscience 33 (9), 3765-3779, 2013 | 56 | 2013 |
Cytosolic proteins lose solubility as amyloid deposits in a transgenic mouse model of Alzheimer-type amyloidosis G Xu, SM Stevens Jr, BD Moore, S McClung, DR Borchelt Human molecular genetics 22 (14), 2765-2774, 2013 | 54 | 2013 |
A novel panel of α-synuclein antibodies reveal distinctive staining profiles in synucleinopathies JKS Dhillon, C Riffe, BD Moore, Y Ran, P Chakrabarty, TE Golde, ... PloS one 12 (9), e0184731, 2017 | 53 | 2017 |
Generation and characterization of new monoclonal antibodies targeting the PHF1 and AT8 epitopes on human tau KH Strang, MS Goodwin, C Riffe, BD Moore, P Chakrabarty, Y Levites, ... Acta neuropathologica communications 5, 1-11, 2017 | 51 | 2017 |
Steroids as γ-secretase modulators JI Jung, TB Ladd, T Kukar, AR Price, BD Moore, EH Koo, TE Golde, ... The FASEB Journal 27 (9), 3775, 2013 | 46 | 2013 |
Retention in endoplasmic reticulum 1 (RER1) modulates amyloid-β (Aβ) production by altering trafficking of γ-secretase and amyloid precursor protein (APP) HJ Park, D Shabashvili, MD Nekorchuk, E Shyqyriu, JI Jung, TB Ladd, ... Journal of Biological Chemistry 287 (48), 40629-40640, 2012 | 42 | 2012 |
Structural insights and functional implications of choline acetyltransferase L Govindasamy, B Pedersen, W Lian, T Kukar, Y Gu, S Jin, ... Journal of structural biology 148 (2), 226-235, 2004 | 40 | 2004 |
Rationally designed dehydroalanine (ΔAla)‐containing peptides inhibit amyloid‐β (Aβ) peptide aggregation V Rangachari, ZS Davey, B Healy, BD Moore, LK Sonoda, B Cusack, ... Biopolymers: Original Research on Biomolecules 91 (6), 456-465, 2009 | 39 | 2009 |