Gr-1+CD115+ Immature Myeloid Suppressor Cells Mediate the Development of Tumor-Induced T Regulatory Cells and T-Cell Anergy in Tumor-Bearing Host B Huang, PY Pan, Q Li, AI Sato, DE Levy, J Bromberg, CM Divino, ... Cancer research 66 (2), 1123-1131, 2006 | 1799 | 2006 |
The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies J Ozao-Choy, G Ma, J Kao, GX Wang, M Meseck, M Sung, M Schwartz, ... Cancer research 69 (6), 2514-2522, 2009 | 612 | 2009 |
Immune stimulatory receptor CD40 is required for T-cell suppression and T regulatory cell activation mediated by myeloid-derived suppressor cells in cancer PY Pan, G Ma, KJ Weber, J Ozao-Choy, G Wang, B Yin, CM Divino, ... Cancer research 70 (1), 99-108, 2010 | 579 | 2010 |
Reversion of immune tolerance in advanced malignancy: modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor function PY Pan, GX Wang, B Yin, J Ozao, T Ku, CM Divino, SH Chen Blood, The Journal of the American Society of Hematology 111 (1), 219-228, 2008 | 423 | 2008 |
Myeloid-derived suppressor cells prevent type 1 diabetes in murine models B Yin, G Ma, CY Yen, Z Zhou, GX Wang, CM Divino, S Casares, SH Chen, ... The Journal of Immunology 185 (10), 5828-5834, 2010 | 204 | 2010 |
Development and function of myeloid-derived suppressor cells generated from mouse embryonic and hematopoietic stem cells Z Zhou, DL French, G Ma, S Eisenstein, Y Chen, CM Divino, G Keller, ... Stem cells 28 (3), 620-632, 2010 | 190 | 2010 |
Blocking immunoinhibitory receptor LILRB2 reprograms tumor-associated myeloid cells and promotes antitumor immunity HM Chen, W van der Touw, YS Wang, K Kang, S Mai, J Zhang, ... The Journal of clinical investigation 128 (12), 5647-5662, 2018 | 180 | 2018 |
Role of immature myeloid Gr-1+ cells in the development of antitumor immunity Q Li, PY Pan, P Gu, D Xu, SH Chen Cancer research 64 (3), 1130-1139, 2004 | 180 | 2004 |
Paired immunoglobin-like receptor-B regulates the suppressive function and fate of myeloid-derived suppressor cells G Ma, PY Pan, S Eisenstein, CM Divino, CA Lowell, T Takai, SH Chen Immunity 34 (3), 385-395, 2011 | 175 | 2011 |
OX40 ligation enhances primary and memory cytotoxic T lymphocyte responses in an immunotherapy for hepatic colon metastases PY Pan, Y Zang, K Weber, ML Meseck, SH Chen Molecular Therapy 6 (4), 528-536, 2002 | 145 | 2002 |
LILRB receptor-mediated regulation of myeloid cell maturation and function W van der Touw, HM Chen, PY Pan, SH Chen Cancer Immunology, Immunotherapy 66, 1079-1087, 2017 | 135 | 2017 |
NK and CD8+ T cell‐mediated eradication of poorly immunogenic B16‐F10 melanoma by the combined action of IL‐12 gene therapy and 4‐1BB costimulation D Xu, P Gu, PY Pan, Q Li, AI Sato, SH Chen International journal of cancer 109 (4), 499-506, 2004 | 131 | 2004 |
Myeloid-derived suppressor cells as an immune parameter in patients with concurrent sunitinib and stereotactic body radiotherapy HM Chen, G Ma, N Gildener-Leapman, S Eisenstein, BA Coakley, J Ozao, ... Clinical Cancer Research 21 (18), 4073-4085, 2015 | 104 | 2015 |
T cell activation with systemic agonistic antibody versus local 4-1BB ligand gene delivery combined with interleukin-12 eradicate liver metastases of breast cancer O Martinet, CM Divino, Y Zang, Y Gan, J Mandeli, S Thung, PY Pan, ... Gene therapy 9 (12), 786-792, 2002 | 88 | 2002 |
Immunoreceptor tyrosine-based inhibitory motif of the IL-4 receptor associates with SH2-containing phosphatases and regulates IL-4-induced proliferation M Kashiwada, CC Giallourakis, PY Pan, PB Rothman The Journal of Immunology 167 (11), 6382-6387, 2001 | 84 | 2001 |
Regulation of dendritic cell function by NK cells: mechanisms underlying the synergism in the combination therapy of IL-12 and 4-1BB activation PY Pan, P Gu, Q Li, D Xu, K Weber, SH Chen The Journal of Immunology 172 (8), 4779-4789, 2004 | 79 | 2004 |
Polarization and reprogramming of myeloid-derived suppressor cells WC Yang, G Ma, SH Chen, PY Pan Journal of molecular cell biology 5 (3), 207-209, 2013 | 78 | 2013 |
Myeloid-derived suppressor cells as a vehicle for tumor-specific oncolytic viral therapy S Eisenstein, BA Coakley, K Briley-Saebo, G Ma, H Chen, M Meseck, ... Cancer research 73 (16), 5003-5015, 2013 | 74 | 2013 |
A phase 1/2 clinical trial of the nitric oxide synthase inhibitor L-NMMA and taxane for treating chemoresistant triple-negative breast cancer AW Chung, K Anand, AC Anselme, AA Chan, N Gupta, LA Venta, ... Science translational medicine 13 (624), eabj5070, 2021 | 65 | 2021 |
In situ recruitment of antigen-presenting cells by intratumoral GM-CSF gene delivery PY Pan, Y Li, Q Li, P Gu, O Martinet, S Thung, SH Chen Cancer Immunology, Immunotherapy 53, 17-25, 2004 | 60 | 2004 |