| Epigenetic reactivation of tumor suppressor genes by a novel small-molecule inhibitor of human DNA methyltransferases B Brueckner, R Garcia Boy, P Siedlecki, T Musch, HC Kliem, ... Cancer research 65 (14), 6305-6311, 2005 | 631 | 2005 |
| Development and evaluation of a deep learning model for protein–ligand binding affinity prediction MM Stepniewska-Dziubinska, P Zielenkiewicz, P Siedlecki Bioinformatics 34 (21), 3666-3674, 2018 | 497 | 2018 |
| Performance of machine-learning scoring functions in structure-based virtual screening M Wójcikowski, PJ Ballester, P Siedlecki Scientific Reports 7 (1), 46710, 2017 | 304 | 2017 |
| Discovery of two novel, small-molecule inhibitors of DNA methylation P Siedlecki, RG Boy, T Musch, B Brueckner, S Suhai, F Lyko, ... Journal of medicinal chemistry 49 (2), 678-683, 2006 | 184 | 2006 |
| Open Drug Discovery Toolkit (ODDT): a new open-source player in the drug discovery field M Wójcikowski, P Zielenkiewicz, P Siedlecki Journal of cheminformatics 7, 1-6, 2015 | 180 | 2015 |
| Mammalian DNA methyltransferases P Siedlecki, P Zielenkiewicz Acta biochimica polonica 53 (2), 245-256, 2006 | 169 | 2006 |
| A specialized histone H1 variant is required for adaptive responses to complex abiotic stress and related DNA methylation in Arabidopsis K Rutowicz, M Puzio, J Halibart-Puzio, M Lirski, M Kotliński, MA Kroteń, ... Plant Physiology 169 (3), 2080-2101, 2015 | 136 | 2015 |
| Development of a protein–ligand extended connectivity (PLEC) fingerprint and its application for binding affinity predictions M Wójcikowski, M Kukiełka, MM Stepniewska-Dziubinska, P Siedlecki Bioinformatics 35 (8), 1334-1341, 2019 | 127 | 2019 |
| Improving detection of protein-ligand binding sites with 3D segmentation MM Stepniewska-Dziubinska, P Zielenkiewicz, P Siedlecki Scientific reports 10 (1), 5035, 2020 | 85 | 2020 |
| Establishment and functional validation of a structural homology model for human DNA methyltransferase 1 P Siedlecki, RG Boy, S Comagic, R Schirrmacher, M Wiessler, ... Biochemical and biophysical research communications 306 (2), 558-563, 2003 | 70 | 2003 |
| Nicotiana tabacum osmotic stress-activated kinase is regulated by phosphorylation on Ser-154 and Ser-158 in the kinase activation loop AM Burza, I Pekala, J Sikora, P Siedlecki, P Malagocki, M Bucholc, ... Journal of Biological Chemistry 281 (45), 34299-34311, 2006 | 69 | 2006 |
| Synthesis and in vitro evaluation of biotinylated RG108: a high affinity compound for studying binding interactions with human DNA methyltransferases E Schirrmacher, C Beck, B Brueckner, F Schmitges, P Siedlecki, ... Bioconjugate chemistry 17 (2), 261-266, 2006 | 55 | 2006 |
| Targeting peroxiredoxin 1 impairs growth of breast cancer cells and potently sensitises these cells to prooxidant agents M Bajor, AO Zych, A Graczyk-Jarzynka, A Muchowicz, M Firczuk, ... British Journal of Cancer 119 (7), 873-884, 2018 | 54 | 2018 |
| Antimicrobial susceptibility profiling and genotyping of Staphylococcus aureus isolates from bovine mastitis in Poland T Jagielski, E Puacz, A Lisowski, P Siedlecki, W Dudziak, J Międzobrodzki, ... Journal of Dairy Science 97 (10), 6122-6128, 2014 | 40 | 2014 |
| Sequence diversity and potential recombination events in the coat protein gene of Apple stem pitting virus B Komorowska, P Siedlecki, S Kaczanowski, B Hasiów-Jaroszewska, ... Virus research 158 (1-2), 263-267, 2011 | 37 | 2011 |
| Novel thienopyrrole glycogen phosphorylase inhibitors: synthesis, in vitro SAR and crystallographic studies PRO Whittamore, MS Addie, SNL Bennett, AM Birch, M Butters, L Godfrey, ... Bioorganic & medicinal chemistry letters 16 (21), 5567-5571, 2006 | 36 | 2006 |
| Molecular and cellular mechanisms influenced by postbiotics R Jastrząb, D Graczyk, P Siedlecki International journal of molecular sciences 22 (24), 13475, 2021 | 31 | 2021 |
| Building machine-learning scoring functions for structure-based prediction of intermolecular binding affinity M Wójcikowski, P Siedlecki, PJ Ballester Docking screens for drug discovery, 1-12, 2019 | 28 | 2019 |
| Rhythmic diel pattern of gene expression in juvenile maize leaf M Jończyk, A Sobkowiak, P Siedlecki, P Biecek, J Trzcinska-Danielewicz, ... PLoS One 6 (8), e23628, 2011 | 16 | 2011 |
| e-LiSe—an online tool for finding needles in the ‘(Medline) haystack’ A Gladki, P Siedlecki, S Kaczanowski, P Zielenkiewicz Bioinformatics 24 (8), 1115-1117, 2008 | 16 | 2008 |
