Copper-catalyzed azide–alkyne cycloaddition (CuAAC) and beyond: new reactivity of copper (I) acetylides JE Hein, VV Fokin Chemical Society Reviews 39 (4), 1302-1315, 2010 | 2528 | 2010 |
Copper (I)-catalyzed cycloaddition of organic azides and 1-iodoalkynes JE Hein, JC Tripp, LB Krasnova, KB Sharpless, VV Fokin Angewandte Chemie (International ed. in English) 48 (43), 8018, 2009 | 565 | 2009 |
Self-driving laboratory for accelerated discovery of thin-film materials BP MacLeod, FGL Parlane, TD Morrissey, F Häse, LM Roch, ... Science Advances 6 (20), eaaz8867, 2020 | 484 | 2020 |
On the origin of single chirality of amino acids and sugars in biogenesis JE Hein, DG Blackmond Accounts of chemical research 45 (12), 2045-2054, 2012 | 206 | 2012 |
Iterative in situ click chemistry creates antibody‐like protein‐capture agents HD Agnew, RD Rohde, SW Millward, A Nag, WS Yeo, JE Hein, SM Pitram, ... Angewandte Chemie International Edition 48 (27), 4944-4948, 2009 | 184 | 2009 |
Data-science driven autonomous process optimization M Christensen, LPE Yunker, F Adedeji, F Häse, LM Roch, T Gensch, ... Communications Chemistry 4 (1), 112, 2021 | 158 | 2021 |
ChemOS: orchestrating autonomous experimentation LM Roch, F Häse, C Kreisbeck, T Tamayo-Mendoza, LPE Yunker, ... Science Robotics 3 (19), eaat5559, 2018 | 157 | 2018 |
Pasteur’s tweezers revisited: on the mechanism of attrition-enhanced deracemization and resolution of chiral conglomerate solids JE Hein, B Huynh Cao, C Viedma, RM Kellogg, DG Blackmond Journal of the American Chemical Society 134 (30), 12629-12636, 2012 | 156 | 2012 |
ChemOS: An orchestration software to democratize autonomous discovery LM Roch, F Häse, A Aspuru-Guzik | 144 | 2020 |
A route to enantiopure RNA precursors from nearly racemic starting materials JE Hein, E Tse, DG Blackmond Nature chemistry 3 (9), 704-706, 2011 | 116 | 2011 |
Halogen Exchange (Halex) Reaction of 5‐Iodo‐1, 2, 3‐triazoles: Synthesis and Applications of 5‐Fluorotriazoles BT Worrell, JE Hein, VV Fokin Angewandte Chemie International Edition 51 (47), 11791-11794, 2012 | 103 | 2012 |
Measuring and suppressing the oxidative damage to DNA during Cu (I)-catalyzed azide–alkyne cycloaddition GR Abel Jr, ZA Calabrese, J Ayco, JE Hein, T Ye Bioconjugate chemistry 27 (3), 698-704, 2016 | 94 | 2016 |
Efficient and Selective Iron-Complex-Catalyzed Hydroboration of Aldehydes UK Das, CS Higman, B Gabidullin, JE Hein, RT Baker ACS Catalysis 8 (2), 1076-1081, 2018 | 84 | 2018 |
Application of continuous preferential crystallization to efficiently access enantiopure chemicals C Rougeot, JE Hein Organic Process Research & Development 19 (12), 1809-1819, 2015 | 84 | 2015 |
Olympus: a benchmarking framework for noisy optimization and experiment planning F Häse, M Aldeghi, RJ Hickman, LM Roch, M Christensen, E Liles, ... Machine Learning: Science and Technology 2 (3), 035021, 2021 | 80 | 2021 |
Automation isn't automatic M Christensen, LPE Yunker, P Shiri, T Zepel, PL Prieto, S Grunert, F Bork, ... Chemical science 12 (47), 15473-15490, 2021 | 80 | 2021 |
One-pot 1, 1-dihydrofluoroalkylation of amines using sulfuryl fluoride M Epifanov, PJ Foth, F Gu, C Barrillon, SS Kanani, CS Higman, JE Hein, ... Journal of the American Chemical Society 140 (48), 16464-16468, 2018 | 80 | 2018 |
Real-time HPLC-MS reaction progress monitoring using an automated analytical platform TC Malig, JDB Koenig, H Situ, NK Chehal, PG Hultin, JE Hein Reaction Chemistry & Engineering 2 (3), 309-314, 2017 | 75 | 2017 |
Enamine carboxylates as stereodetermining intermediates in prolinate catalysis JE Hein, J Burés, Y Lam, M Hughes, KN Houk, A Armstrong, ... Organic letters 13 (20), 5644-5647, 2011 | 73 | 2011 |
Automated experimentation powers data science in chemistry Y Shi, PL Prieto, T Zepel, S Grunert, JE Hein Accounts of Chemical Research 54 (3), 546-555, 2021 | 72 | 2021 |