Impedance changes and fibrous tissue growth after cochlear implantation are correlated and can be reduced using a dexamethasone eluting electrode M Wilk, R Hessler, K Mugridge, C Jolly, M Fehr, T Lenarz, V Scheper PloS one 11 (2), e0147552, 2016 | 178 | 2016 |
Effects of delayed treatment with combined GDNF and continuous electrical stimulation on spiral ganglion cell survival in deafened guinea pigs V Scheper, G Paasche, JM Miller, A Warnecke, N Berkingali, T Lenarz, ... Journal of neuroscience research 87 (6), 1389-1399, 2009 | 86 | 2009 |
The neural bases of tinnitus: lessons from deafness and cochlear implants M Knipper, P Van Dijk, H Schulze, B Mazurek, P Krauss, V Scheper, ... Journal of Neuroscience 40 (38), 7190-7202, 2020 | 83 | 2020 |
Brain-derived neurotrophic factor/glial cell line-derived neurotrophic factor survival effects on auditory neurons are not limited by dexamethasone P Wefstaedt, V Scheper, T Lenarz, T Stöver Neuroreport 16 (18), 2011-2014, 2005 | 69 | 2005 |
Proteome analysis of human perilymph using an intraoperative sampling method HA Schmitt, A Pich, A Schröder, V Scheper, G Lilli, G Reuter, T Lenarz Journal of Proteome Research 16 (5), 1911-1923, 2017 | 63 | 2017 |
Potential novel drug carriers for inner ear treatment: hyperbranched polylysine and lipid nanocapsules V Scheper, M Wolf, M Scholl, Z Kadlecova, T Perrier, HA Klok, P Saulnier, ... Nanomedicine 4 (6), 623-635, 2009 | 61 | 2009 |
Stable release of BDNF from the fibroblast cell line NIH3T3 grown on silicone elastomers enhances survival of spiral ganglion cells in vitro and in vivo A Warnecke, S Sasse, GI Wenzel, A Hoffmann, G Gross, G Paasche, ... Hearing Research 289 (1-2), 86-97, 2012 | 56 | 2012 |
Congenital deafness affects deep layers in primary and secondary auditory cortex C Berger, D Kühne, V Scheper, A Kral Journal of Comparative Neurology 525 (14), 3110-3125, 2017 | 51 | 2017 |
Neuronal survival, morphology and outgrowth of spiral ganglion neurons using a defined growth factor combination J Schwieger, A Warnecke, T Lenarz, KH Esser, V Scheper PLoS One 10 (8), e0133680, 2015 | 51 | 2015 |
Novel Screen to Assess Bactericidal Activity of Compounds Against Non-replicating Mycobacterium abscessus BJ Berube, L Castro, D Russell, Y Ovechkina, T Parish Frontiers in Microbiology 9, 2417, 2018 | 44* | 2018 |
Local inner ear application of dexamethasone in cochlear implant models is safe for auditory neurons and increases the neuroprotective effect of chronic electrical stimulation V Scheper, R Hessler, M Hütten, M Wilk, C Jolly, T Lenarz, G Paasche PLoS One 12 (8), e0183820, 2017 | 44 | 2017 |
In vitro and in vivo evaluation of a hydrogel reservoir as a continuous drug delivery system for inner ear treatment M Hütten, A Dhanasingh, R Hessler, T Stöver, KH Esser, M Möller, ... PloS one 9 (8), e104564, 2014 | 44 | 2014 |
Stem cell based drug delivery for protection of auditory neurons in a guinea pig model of cochlear implantation V Scheper, A Hoffmann, MM Gepp, A Schulz, A Hamm, C Pannier, ... Frontiers in Cellular Neuroscience 13, 177, 2019 | 43 | 2019 |
Establishment of a long-term spiral ganglion neuron culture with reduced glial cell number: Effects of AraC on cell composition and neurons J Schwieger, KH Esser, T Lenarz, V Scheper Journal of neuroscience methods 268, 106-116, 2016 | 41 | 2016 |
BDNF‐overexpressing human mesenchymal stem cells mediate increased neuronal protection in vitro V Scheper, J Schwieger, A Hamm, T Lenarz, A Hoffmann Journal of neuroscience research 97 (11), 1414-1429, 2019 | 38 | 2019 |
Lipidic nanocapsule drug delivery: neuronal protection for cochlear implant optimization H Meyer, T Stöver, F Fouchet, G Bastiat, P Saulnier, W Bäumer, T Lenarz, ... International journal of nanomedicine, 2449-2464, 2012 | 38 | 2012 |
Biodegradable polymeric coatings on cochlear implant surfaces and their influence on spiral ganglion cell survival P Ceschi, A Bohl, K Sternberg, A Neumeister, V Senz, KP Schmitz, ... Journal of Biomedical Materials Research Part B: Applied Biomaterials 102 (6 …, 2014 | 32 | 2014 |
Alginate-encapsulated brain-derived neurotrophic factor–overexpressing mesenchymal stem cells are a promising drug delivery system for protection of auditory neurons J Schwieger, A Hamm, MM Gepp, A Schulz, A Hoffmann, T Lenarz, ... Journal of tissue engineering 11, 2041731420911313, 2020 | 29 | 2020 |
Phosphodiesterase type 4 inhibitor rolipram improves survival of spiral ganglion neurons in vitro K Kranz, A Warnecke, T Lenarz, M Durisin, V Scheper PLoS One 9 (3), e92157, 2014 | 29 | 2014 |
Artemin improves survival of spiral ganglion neurons in vivo and in vitro A Warnecke, V Scheper, I Buhr, GI Wenzel, K Wissel, G Paasche, ... Neuroreport 21 (7), 517-521, 2010 | 28 | 2010 |