High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells A Sharma, PW Burridge, WL McKeithan, R Serrano, P Shukla, N Sayed, ... Science translational medicine 9 (377), eaaf2584, 2017 | 363 | 2017 |
Internalization of isolated functional mitochondria: involvement of macropinocytosis T Kitani, D Kami, S Matoba, S Gojo Journal of cellular and molecular medicine 18 (8), 1694-1703, 2014 | 202 | 2014 |
Human-induced pluripotent stem cell model of trastuzumab-induced cardiac dysfunction in patients with breast cancer T Kitani, SG Ong, CK Lam, JW Rhee, JZ Zhang, A Oikonomopoulos, N Ma, ... Circulation 139 (21), 2451-2465, 2019 | 165 | 2019 |
Use of human induced pluripotent stem cell–derived cardiomyocytes to assess drug cardiotoxicity A Sharma, WL McKeithan, R Serrano, T Kitani, PW Burridge, ... Nature protocols 13 (12), 3018-3041, 2018 | 143 | 2018 |
Determining the pathogenicity of a genomic variant of uncertain significance using CRISPR/Cas9 and human-induced pluripotent stem cells N Ma, JZ Zhang, I Itzhaki, SL Zhang, H Chen, F Haddad, T Kitani, ... Circulation 138 (23), 2666-2681, 2018 | 134 | 2018 |
A human iPSC double-reporter system enables purification of cardiac lineage subpopulations with distinct function and drug response profiles JZ Zhang, V Termglinchan, NY Shao, I Itzhaki, C Liu, N Ma, L Tian, ... Cell Stem Cell 24 (5), 802-811. e5, 2019 | 121 | 2019 |
Pluripotent stem cell-derived cardiomyocytes as a platform for cell therapy applications: progress and hurdles for clinical translation A Oikonomopoulos, T Kitani, JC Wu Molecular Therapy 26 (7), 1624-1634, 2018 | 76 | 2018 |
Novel detergent for whole organ tissue engineering T Kawasaki, Y Kirita, D Kami, T Kitani, C Ozaki, Y Itakura, M Toyoda, ... Journal of biomedical materials research Part A 103 (10), 3364-3373, 2015 | 62 | 2015 |
Single-cell RNA sequencing of human embryonic stem cell differentiation delineates adverse effects of nicotine on embryonic development H Guo, L Tian, JZ Zhang, T Kitani, DT Paik, WH Lee, JC Wu Stem Cell Reports 12 (4), 772-786, 2019 | 57 | 2019 |
SETD7 drives cardiac lineage commitment through stage-specific transcriptional activation J Lee, NY Shao, DT Paik, H Wu, H Guo, V Termglinchan, JM Churko, ... Cell Stem Cell 22 (3), 428-444. e5, 2018 | 51 | 2018 |
Large-scale cell production of stem cells for clinical application using the automated cell processing machine D Kami, K Watakabe, M Yamazaki-Inoue, K Minami, T Kitani, Y Itakura, ... BMC biotechnology 13, 1-9, 2013 | 49 | 2013 |
TAT‐dextran–mediated mitochondrial transfer enhances recovery from models of reperfusion injury in cultured cardiomyocytes H Maeda, D Kami, R Maeda, Y Murata, J Jo, T Kitani, Y Tabata, S Matoba, ... Journal of cellular and molecular medicine 24 (9), 5007-5020, 2020 | 44 | 2020 |
Direct human mitochondrial transfer: a novel concept based on the endosymbiotic theory T Kitani, D Kami, T Kawasaki, M Nakata, S Matoba, S Gojo Transplantation proceedings 46 (4), 1233-1236, 2014 | 43 | 2014 |
Identifying the transcriptome signatures of calcium channel blockers in human induced pluripotent stem cell–derived cardiomyocytes CK Lam, L Tian, N Belbachir, A Wnorowski, R Shrestha, N Ma, T Kitani, ... Circulation research 125 (2), 212-222, 2019 | 36 | 2019 |
Pleiotropic functions of magnetic nanoparticles for ex vivo gene transfer D Kami, T Kitani, T Kishida, O Mazda, M Toyoda, A Tomitaka, S Ota, ... Nanomedicine: Nanotechnology, Biology and Medicine 10 (6), 1165-1174, 2014 | 29 | 2014 |
High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells. Sci Transl Med 9 A Sharma, PW Burridge, WL McKeithan, R Serrano, P Shukla, N Sayed, ... | 21 | 2017 |
RNA sequencing analysis of induced pluripotent stem cell-derived cardiomyocytes from congenital heart disease patients T Kitani, L Tian, T Zhang, I Itzhaki, JZ Zhang, N Ma, C Liu, JW Rhee, ... Circulation research 126 (7), 923-925, 2020 | 19 | 2020 |
The DEAD-box RNA-binding protein DDX6 regulates parental RNA decay for cellular reprogramming to pluripotency D Kami, T Kitani, A Nakamura, N Wakui, R Mizutani, M Ohue, F Kametani, ... PLoS One 13 (10), e0203708, 2018 | 17 | 2018 |
Cardiac mesenchymal progenitors differentiate into adipocytes via Klf4 and c-Myc D Kami, T Kitani, T Kawasaki, S Gojo Cell death & disease 7 (4), e2190-e2190, 2016 | 17 | 2016 |
Molecular Signatures of Beneficial Class Effects of Statins on Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes L Tian, A Oikonomopoulos, C Liu, T Kitani, R Shrestha, CL Chen, SG Ong, ... Circulation 141 (14), 1208-1210, 2020 | 8 | 2020 |