| Multidrug resistance-associated proteins 3, 4, and 5 P Borst, C de Wolf, K van de Wetering Pflügers Archiv-European Journal of Physiology 453, 661-673, 2007 | 382 | 2007 |
| Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer S Rottenberg, AOH Nygren, M Pajic, FWB van Leeuwen, ... Proceedings of the National Academy of Sciences 104 (29), 12117-12122, 2007 | 366 | 2007 |
| Collectins: players of the innate immune system JK van de Wetering, LMG van Golde, JJ Batenburg European Journal of Biochemistry 271 (7), 1229-1249, 2004 | 330 | 2004 |
| ABCC6–mediated ATP secretion by the liver is the main source of the mineralization inhibitor inorganic pyrophosphate in the systemic circulation—brief report RS Jansen, S Duijst, S Mahakena, D Sommer, F Szeri, A Váradi, A Plomp, ... Arteriosclerosis, thrombosis, and vascular biology 34 (9), 1985-1989, 2014 | 297 | 2014 |
| ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release RS Jansen, A Küçükosmanoğlu, M De Haas, S Sapthu, JA Otero, ... Proceedings of the National Academy of Sciences 110 (50), 20206-20211, 2013 | 251 | 2013 |
| Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception N Zelcer, K van de Wetering, M Hillebrand, E Sarton, A Kuil, PR Wielinga, ... Proceedings of the National Academy of Sciences 102 (20), 7274-7279, 2005 | 248 | 2005 |
| Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides N Zelcer, K van de Wetering, R de Waart, GL Scheffer, HU Marschall, ... Journal of hepatology 44 (4), 768-775, 2006 | 210 | 2006 |
| Identification of multidrug resistance protein 1 (MRP1/ABCC1) as a molecular gate for cellular export of cobalamin R Beedholm-Ebsen, K van de Wetering, T Hardlei, E Nexø, P Borst, ... Blood, The Journal of the American Society of Hematology 115 (8), 1632-1639, 2010 | 176 | 2010 |
| Intestinal breast cancer resistance protein (BCRP)/Bcrp1 and multidrug resistance protein 3 (MRP3)/Mrp3 are involved in the pharmacokinetics of resveratrol K van de Wetering, A Burkon, W Feddema, A Bot, H de Jonge, V Somoza, ... Molecular pharmacology 75 (4), 876-885, 2009 | 160 | 2009 |
| An exercise-inducible metabolite that suppresses feeding and obesity VL Li, Y He, K Contrepois, H Liu, JT Kim, AL Wiggenhorn, JT Tanzo, ... Nature 606 (7915), 785-790, 2022 | 150 | 2022 |
| MRP2 and 3 in health and disease P Borst, N Zelcer, K Van De Wetering Cancer letters 234 (1), 51-61, 2006 | 144 | 2006 |
| Multidrug resistance proteins 2 and 3 provide alternative routes for hepatic excretion of morphine-glucuronides K van de Wetering, N Zelcer, A Kuil, W Feddema, M Hillebrand, ... Molecular pharmacology 72 (2), 387-394, 2007 | 128 | 2007 |
| Functionally overlapping roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate in vivo MLH Vlaming, Z Pala, A van Esch, E Wagenaar, DR de Waart, ... Clinical Cancer Research 15 (9), 3084-3093, 2009 | 123 | 2009 |
| Oral administration of pyrophosphate inhibits connective tissue calcification D Dedinszki, F Szeri, E Kozák, V Pomozi, N Tőkési, TR Mezei, K Merczel, ... EMBO molecular medicine 9 (11), 1463-1470, 2017 | 113 | 2017 |
| Characteristics of surfactant protein A and D binding to lipoteichoic acid and peptidoglycan, 2 major cell wall components of gram-positive bacteria J de Wetering, M Van Eijk, LMG Van Golde, T Hartung, JAG Van Strijp, ... Journal of Infectious Diseases 184 (9), 1143, 2001 | 107 | 2001 |
| Abcc2 (Mrp2), Abcc3 (Mrp3), and Abcg2 (Bcrp1) are the main determinants for rapid elimination of methotrexate and its toxic metabolite 7-hydroxymethotrexate in vivo MLH Vlaming, A van Esch, Z Pala, E Wagenaar, K van de Wetering, ... Molecular cancer therapeutics 8 (12), 3350-3359, 2009 | 91 | 2009 |
| On the putative co-transport of drugs by multidrug resistance proteins P Borst, N Zelcer, K Van de Wetering, B Poolman FEBS letters 580 (4), 1085-1093, 2006 | 91 | 2006 |
| N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids RS Jansen, R Addie, R Merkx, A Fish, S Mahakena, OB Bleijerveld, ... Proceedings of the National Academy of Sciences 112 (21), 6601-6606, 2015 | 83 | 2015 |
| Contribution of the drug transporter ABCG2 (breast cancer resistance protein) to resistance against anticancer nucleosides C De Wolf, R Jansen, H Yamaguchi, M De Haas, K Van De Wetering, ... Molecular cancer therapeutics 7 (9), 3092-3102, 2008 | 83 | 2008 |
| Does the absence of ABCC6 (multidrug resistance protein 6) in patients with Pseudoxanthoma elasticum prevent the liver from providing sufficient vitamin K to the periphery? P Borst, K van de Wetering, R Schlingemann Cell Cycle 7 (11), 1575-1579, 2008 | 83 | 2008 |
