A critical review of the probable reasons for the poor variable bioavailability of rifampicin from anti-tubercular fixed-dose combination (FDC) products, and the likely … S Singh, TT Mariappan, R Shankar, N Sarda, B Singh International journal of pharmaceutics 228 (1-2), 5-17, 2001 | 145 | 2001 |
Regional gastrointestinal permeability of rifampicin and isoniazid (alone and their combination) in the rat TT Mariappan, S Singh The international Journal of Tuberculosis and Lung Disease 7 (8), 797-803, 2003 | 115 | 2003 |
The reason for an increase in decomposition of rifampicin in the presence of isoniazid under acid conditions S Singh, TT Mariappan, N Sharda, S Kumar, AK Chakraborti Pharmacy and Pharmacology Communications 6 (9), 405-410, 2000 | 104 | 2000 |
Selective IRAK4 inhibition attenuates disease in murine lupus models and demonstrates steroid sparing activity S Dudhgaonkar, S Ranade, J Nagar, S Subramani, DS Prasad, ... The Journal of Immunology 198 (3), 1308-1319, 2017 | 71 | 2017 |
The physical and chemical stability of anti-tuberculosis fixed-dose combination products under accelerated climatic conditions H Bhutani, TT Mariappan, S Singh The International Journal of Tuberculosis and Lung Disease 8 (9), 1073-1080, 2004 | 63 | 2004 |
Degradation of rifampicin, isoniazid and pyrazinamide from prepared mixtures and marketed single and combination products under acid conditions S Singh, TT Mariappan, N SHARDA, B SINGH Pharmacy and Pharmacology Communications 6 (11), 491-494, 2000 | 62 | 2000 |
Coproporphyrin-I: a fluorescent, endogenous optimal probe substrate for ABCC2 (MRP2) suitable for vesicle-based MRP2 inhibition assay RR Gilibili, S Chatterjee, P Bagul, KW Mosure, BV Murali, TT Mariappan, ... Drug Metabolism and Disposition 45 (6), 604-611, 2017 | 56 | 2017 |
Evidence of efflux-mediated and saturable absorption of rifampicin in rat intestine using the ligated loop and everted gut sac techniques TT Mariappan, S Singh Molecular pharmaceutics 1 (5), 363-367, 2004 | 51 | 2004 |
Evidence for the validity of pyridoxic acid (PDA) as a plasma-based endogenous probe for OAT1 and OAT3 function in healthy subjects H Shen, VK Holenarsipur, TT Mariappan, DM Drexler, JL Cantone, ... Journal of Pharmacology and Experimental Therapeutics 368 (1), 136-145, 2019 | 47 | 2019 |
Behavior of uptake of moisture by drugs and excipients under accelerated conditions of temperature and humidity in the absence and the presence of light. 1. Pure anti … S Singh, H Bhutani, TT Mariappan, H Kaur, M Bajaj, SP Pakhale International journal of pharmaceutics 245 (1-2), 37-44, 2002 | 43 | 2002 |
Insight into tissue unbound concentration: utility in drug discovery and development T Thanga Mariappan, S Mandlekar, P Marathe Current drug metabolism 14 (3), 324-340, 2013 | 40 | 2013 |
Endogenous biomarkers to assess drug-drug interactions by drug transporters and enzymes TT Mariappan, H Shen, P Marathe Current Drug Metabolism 18 (8), 757-768, 2017 | 34 | 2017 |
Overestimation of rifampicin during colorimetric analysis of anti-tuberculosis products containing isoniazid due to formation of isonicotinyl hydrazone TT Mariappan, KC Jindal, S Singh Journal of pharmaceutical and biomedical analysis 36 (4), 905-908, 2004 | 31 | 2004 |
Behavior of moisture gain and equilibrium moisture contents (EMC) of various drug substances and correlation with compendial information on hygroscopicity and loss on drying NA Visalakshi, TT Mariappan, H Bhutani, S Singh Pharmaceutical development and technology 10 (4), 489-497, 2005 | 28 | 2005 |
An explanation for the physical instability of a marketed fixed dose combination (FDC) formulation containing isoniazid and ethambutol and proposed solutions H Bhutani, TT Mariappan, S Singh Drug development and industrial pharmacy 30 (6), 667-672, 2004 | 28 | 2004 |
A Validated Reversed‐Phase (C18) HPLC Method for Simultaneous Determination of Rifampicin, Isoniazid and Pyrazinamide in USP Dissolution Medium and … TT Mariappan, B SINGH, S SINGH Pharmacy and Pharmacology Communications 6 (8), 345-349, 2000 | 28 | 2000 |
Detection of Weak Organic Anion–Transporting Polypeptide 1B Inhibition by Probenecid with Plasma-Based Coproporphyrin in Humans Y Zhang, VK Holenarsipur, H Kandoussi, J Zeng, TT Mariappan, M Sinz, ... Drug Metabolism and Disposition 48 (10), 841-848, 2020 | 26 | 2020 |
A modified serial blood sampling technique and utility of dried-blood spot technique in estimation of blood concentration: application in mouse pharmacokinetics V Kurawattimath, K Pocha, T Thanga Mariappan, RK Trivedi, S Mandlekar European journal of drug metabolism and pharmacokinetics 37, 23-30, 2012 | 26 | 2012 |
Positioning of rifampicin in the biopharmaceutics classification system (BCS) TT Mariappan, S Singh Clinical Research and Regulatory Affairs 23 (1), 1-10, 2006 | 26 | 2006 |
Quality problems of anti-tuberculosis Fixed-dose Combinations (FDCS) A way forward. S Singh, H Bhutani, TT Mariappan | 26 | 2006 |