Design, synthesis and biological investigation of certain pyrazole-3-carboxylic acid derivatives as novel carriers for nitric oxide ESMN Abdel-Hafez, GEDAA Abuo-Rahma, M Abdel-Aziz, MF Radwan, ... Bioorganic & medicinal chemistry 17 (11), 3829-3837, 2009 | 82 | 2009 |
Design, synthesis, mechanistic studies and in silico ADME predictions of benzimidazole derivatives as novel antifungal agents MM Morcoss, MN El Shimaa, RA Ibrahem, HM Abdel-Rahman, ... Bioorganic chemistry 101, 103956, 2020 | 74 | 2020 |
Comprehensive review for anticancer hybridized multitargeting HDAC inhibitors AKA Bass, MS El-Zoghbi, ESM Nageeb, MFA Mohamed, M Badr, ... European journal of medicinal chemistry 209, 112904, 2021 | 73 | 2021 |
Synthesis, antiproliferative, anti-tubulin activity, and docking study of new 1, 2, 4-triazoles as potential combretastatin analogues M Mustafa, D Abdelhamid, ESMN Abdelhafez, MAA Ibrahim, ... European journal of medicinal chemistry 141, 293-305, 2017 | 60 | 2017 |
Current trends and future directions of fluoroquinolones HHH Mohammed, GEDAA Abuo-Rahma, SH Abbas, ES Abdelhafez Current Medicinal Chemistry 26 (17), 3132-3149, 2019 | 55 | 2019 |
Design, synthesis, molecular docking, anti-Proteus mirabilis and urease inhibition of new fluoroquinolone carboxylic acid derivatives MAA Abdullah, GEDAA Abuo-Rahma, ESMN Abdelhafez, HA Hassan, ... Bioorganic Chemistry 70, 1-11, 2017 | 46 | 2017 |
New antiproliferative 7-(4-(N-substituted carbamoylmethyl) piperazin-1-yl) derivatives of ciprofloxacin induce cell cycle arrest at G2/M phase HHH Mohammed, AA Abd El-Hafeez, SH Abbas, ESMN Abdelhafez, ... Bioorganic & medicinal chemistry 24 (19), 4636-4646, 2016 | 38 | 2016 |
New quinoline-2-one/pyrazole derivatives; design, synthesis, molecular docking, anti-apoptotic evaluation, and caspase-3 inhibition assay AA Aly, SM Sayed, ESMN Abdelhafez, SMN Abdelhafez, WY Abdelzaher, ... Bioorganic chemistry 94, 103348, 2020 | 33 | 2020 |
Lossen rearrangements under Heck reaction conditions ESMN AbdelHafez, OM Aly, GEDAA Abuo‐Rahma, SB King Advanced Synthesis & Catalysis 356 (16), 3456-3464, 2014 | 26 | 2014 |
Novel Benzimidazole/Hydrazone Derivatives as Promising Anticancer Lead Compounds: Design, Synthesis, and Molecular Docking Study MM Morcoss, ES Abdelhafez, HM Abdel-Rahman, M Abdel-Aziz, A El-Ella, ... Journal of advanced Biomedical and Pharmaceutical Sciences 3 (2), 45-52, 2020 | 23 | 2020 |
Design, synthesis and molecular docking of new N-4-piperazinyl ciprofloxacin-triazole hybrids with potential antimicrobial activity HHH Mohammed, ESMN Abdelhafez, SH Abbas, GAI Moustafa, G Hauk, ... Bioorganic chemistry 88, 102952, 2019 | 20 | 2019 |
Utilization of cyanopyridine in design and synthesis of first-in-class anticancer dual acting PIM-1 kinase/HDAC inhibitors AKA Bass, ESM Nageeb, MS El-Zoghbi, MFA Mohamed, M Badr, ... Bioorganic Chemistry 119, 105564, 2022 | 19 | 2022 |
Design, synthesis, and molecular docking of paracyclophanyl-thiazole hybrids as novel CDK1 inhibitors and apoptosis inducing anti-melanoma agents AA Aly, S Bräse, AA Hassan, NK Mohamed, LEA El-Haleem, M Nieger, ... Molecules 25 (23), 5569, 2020 | 19 | 2020 |
Fluoroquinolones as urease inhibitors: anti-Proteus mirabilis activity and molecular docking studies MA Abdullah, RMA El-Baky, HA Hassan, ESMN Abdelhafez, ... Am J Microbiol Res 4 (3), 81-84, 2016 | 18 | 2016 |
New paracyclophanylthiazoles with anti-leukemia activity: Design, synthesis, molecular docking, and mechanistic studies AA Aly, S Bräse, AA Hassan, NK Mohamed, LE Abd El-Haleem, M Nieger, ... Molecules 25 (13), 3089, 2020 | 17 | 2020 |
3-Cyano-2-oxa-pyridines: a promising template for diverse pharmacological activities AK Bass, E Abdelhafez, M El-Zoghbi, MFA Mohamed, M Badr, ... Journal of advanced Biomedical and Pharmaceutical Sciences 4 (2), 81-86, 2021 | 16 | 2021 |
Synthesis, molecular docking, antimicrobial evaluation, and DNA cleavage assay of new thiadiazole/oxadiazole ciprofloxacin derivatives HHH Mohammed, SH Abbas, ESMN Abdelhafez, JM Berger, S Mitarai, ... Monatshefte für Chemie-Chemical Monthly 150, 1809-1824, 2019 | 16 | 2019 |
Design, synthesis, and DNA interaction studies of furo-imidazo [3.3. 3] propellane derivatives: Potential anticancer agents AA Hassan, AA Aly, NK Mohamed, KM El Shaieb, MM Makhlouf, ... Bioorganic chemistry 85, 585-599, 2019 | 16 | 2019 |
Design, Synthesis, Molecular Docking, Antiapoptotic and Caspase-3 Inhibition of New 1,2,3-Triazole/Bis-2(1H)-Quinolinone Hybrids EM El-Sheref, AA Aly, MB Alshammari, AB Brown, SMN Abdel-Hafez, ... Molecules 25 (21), 5057, 2020 | 13 | 2020 |
Tubulin inhibitors: Discovery of a new scaffold targeting extra-binding residues within the colchicine site through anchoring substituents properly adapted to their pocket by a … RM Maklad, ESMN AbdelHafez, D Abdelhamid, OM Aly Bioorganic Chemistry 99, 103767, 2020 | 10 | 2020 |