Pharmacological blockade of aquaporin-1 water channel by AqB013 restricts migration and invasiveness of colon cancer cells and prevents endothelial tube formation in vitro HS Dorward, A Du, MA Bruhn, J Wrin, JV Pei, A Evdokiou, TJ Price, ... Journal of Experimental & Clinical Cancer Research 35, 1-9, 2016 | 81 | 2016 |
Divalent cations regulate the ion conductance properties of diverse classes of aquaporins M Kourghi, S Nourmohammadi, JV Pei, J Qiu, S McGaughey, SD Tyerman, ... International journal of molecular sciences 18 (11), 2323, 2017 | 72 | 2017 |
Bumetanide derivatives AqB007 and AqB011 selectively block the aquaporin-1 ion channel conductance and slow cancer cell migration M Kourghi, JV Pei, ML De Ieso, G Flynn, AJ Yool Molecular pharmacology 89 (1), 133-140, 2016 | 70 | 2016 |
Differential inhibition of water and ion channel activities of mammalian aquaporin-1 by two structurally related bacopaside compounds derived from the medicinal plant Bacopa … JV Pei, M Kourghi, ML De Ieso, EM Campbell, HS Dorward, ... Molecular pharmacology 90 (4), 496-507, 2016 | 63 | 2016 |
The Purified Extract from the Medicinal Plant Bacopa monnieri, Bacopaside II, Inhibits Growth of Colon Cancer Cells In Vitro by Inducing Cell Cycle Arrest and … E Smith, HM Palethorpe, Y Tomita, JV Pei, AR Townsend, TJ Price, ... Cells 7 (7), 81, 2018 | 56 | 2018 |
Effect of compound kushen injection, a natural compound mixture, and its identified chemical components on migration and invasion of colon, brain, and breast cancer cell lines S Nourmohammadi, TN Aung, J Cui, JV Pei, ML De Ieso, Y Harata-Lee, ... Frontiers in oncology 9, 314, 2019 | 54 | 2019 |
An accurate and cost-effective alternative method for measuring cell migration with the circular wound closure assay ML De Ieso, JV Pei Bioscience reports 38 (5), BSR20180698, 2018 | 46 | 2018 |
Fundamental structural and functional properties of Aquaporin ion channels found across the kingdoms of life M Kourghi, JV Pei, ML De Ieso, S Nourmohammadi, PH Chow, AJ Yool Clinical and Experimental Pharmacology and Physiology 45 (4), 401-409, 2018 | 46 | 2018 |
The aquaporin 1 inhibitor bacopaside II reduces endothelial cell migration and tubulogenesis and induces apoptosis HM Palethorpe, Y Tomita, E Smith, JV Pei, AR Townsend, TJ Price, ... International journal of molecular sciences 19 (3), 653, 2018 | 43 | 2018 |
Combined pharmacological administration of AQP1 ion channel blocker AqB011 and water channel blocker Bacopaside II amplifies inhibition of colon cancer cell migration ML De Ieso, JV Pei, S Nourmohammadi, E Smith, PH Chow, M Kourghi, ... Scientific reports 9 (1), 12635, 2019 | 40 | 2019 |
Stereoselective anti-cancer activities of ginsenoside Rg3 on triple negative breast cancer cell models M Nakhjavani, HM Palethorpe, Y Tomita, E Smith, TJ Price, AJ Yool, ... Pharmaceuticals 12 (3), 117, 2019 | 38 | 2019 |
Molecular and functional characterization of multiple aquaporin water channel proteins from the western tarnished plant bug, Lygus hesperus JA Fabrick, J Pei, JJ Hull, AJ Yool Insect Biochemistry and Molecular Biology 45, 125-140, 2014 | 35 | 2014 |
Rhubarb extract partially improves mucosal integrity in chemotherapy-induced intestinal mucositis JE Bajic, GL Eden, LS Lampton, KY Cheah, KA Lymn, JV Pei, AJ Yool, ... World Journal of Gastroenterology 22 (37), 8322, 2016 | 29 | 2016 |
5-hydroxymethyl-furfural and structurally related compounds block the ion conductance in human aquaporin-1 channels and slow cancer cell migration and invasion PH Chow, M Kourghi, JV Pei, S Nourmohammadi, AJ Yool Molecular Pharmacology 98 (1), 38-48, 2020 | 28 | 2020 |
A G358S mutation in the Plasmodium falciparum Na+ pump PfATP4 confers clinically-relevant resistance to cipargamin D Qiu, JV Pei, JEO Rosling, V Thathy, D Li, Y Xue, JD Tanner, ... Nature communications 13 (1), 5746, 2022 | 27 | 2022 |
Photoswitchable calcium sensor:‘On’–‘Off’sensing in cells or with microstructured optical fibers S Heng, AM Mak, R Kostecki, X Zhang, J Pei, DB Stubing, ... Sensors and Actuators B: Chemical 252, 965-972, 2017 | 27 | 2017 |
Identification of loop D domain amino acids in the human Aquaporin-1 channel involved in activation of the ionic conductance and inhibition by AqB011 M Kourghi, ML De Ieso, S Nourmohammadi, JV Pei, AJ Yool Frontiers in chemistry 6, 142, 2018 | 26 | 2018 |
Development of a photoswitchable lithium-sensitive probe to analyze nonselective cation channel activity in migrating cancer cells JV Pei, S Heng, ML De Ieso, G Sylvia, M Kourghi, S Nourmohammadi, ... Molecular Pharmacology 95 (5), 573-583, 2019 | 22 | 2019 |
Spiropyran‐Based Nanocarrier: A New Zn2+‐Responsive Delivery System with Real‐Time Intracellular Sensing Capabilities S Heng, X Zhang, J Pei, A Adwal, P Reineck, BC Gibson, MR Hutchinson, ... Chemistry–A European Journal 25 (3), 854-862, 2019 | 22 | 2019 |
A rationally designed reversible ‘turn-off’sensor for glutathione S Heng, X Zhang, J Pei, AD Abell Biosensors 7 (3), 36, 2017 | 17 | 2017 |