Epigenetic reprogramming of cancer cells via targeted DNA methylation AG Rivenbark, S Stolzenburg, AS Beltran, X Yuan, MG Rots, BD Strahl, ... Epigenetics 7 (4), 350-360, 2012 | 335 | 2012 |
Breastmilk is a novel source of stem cells with multilineage differentiation potential F Hassiotou, A Beltran, E Chetwynd, AM Stuebe, AJ Twigger, P Metzger, ... Stem cells 30 (10), 2164-2174, 2012 | 331 | 2012 |
Systemic delivery of modified mRNA encoding herpes simplex virus 1 thymidine kinase for targeted cancer gene therapy Y Wang, H Su, Y Yang, Y Hu, L Zhang, P Blancafort, L Huang Molecular Therapy 21 (2), 358-367, 2013 | 316 | 2013 |
Development of zinc finger domains for recognition of the 5′-CNN-3′ family DNA sequences and their use in the construction of artificial transcription factors B Dreier, RP Fuller, DJ Segal, CV Lund, P Blancafort, A Huber, B Koksch, ... Journal of Biological Chemistry 280 (42), 35588-35597, 2005 | 259 | 2005 |
Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins DJ Segal, RR Beerli, P Blancafort, B Dreier, K Effertz, A Huber, B Koksch, ... Biochemistry 42 (7), 2137-2148, 2003 | 249 | 2003 |
Designing transcription factor architectures for drug discovery P Blancafort, DJ Segal, CF Barbas Molecular pharmacology 66 (6), 1361-1371, 2004 | 226 | 2004 |
Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer S Stolzenburg, MG Rots, AS Beltran, AG Rivenbark, X Yuan, H Qian, ... Nucleic acids research 40 (14), 6725-6740, 2012 | 191 | 2012 |
Scanning the human genome with combinatorial transcription factor libraries P Blancafort, L Magnenat, CF Barbas III Nature biotechnology 21 (3), 269-274, 2003 | 167 | 2003 |
Hallmarks of cancer: The CRISPR generation C Moses, B Garcia-Bloj, AR Harvey, P Blancafort European Journal of Cancer 93, 10-18, 2018 | 124 | 2018 |
Synthetically controlling dendrimer flexibility improves delivery of large plasmid DNA JA Kretzmann, D Ho, CW Evans, JHC Plani-Lam, B Garcia-Bloj, ... Chemical science 8 (4), 2923-2930, 2017 | 121 | 2017 |
Re-activation of a dormant tumor suppressor gene maspin by designed transcription factors A Beltran, S Parikh, Y Liu, BD Cuevas, GL Johnson, BW Futscher, ... Oncogene 26 (19), 2791-2798, 2007 | 120 | 2007 |
Honeybee venom and melittin suppress growth factor receptor activation in HER2-enriched and triple-negative breast cancer C Duffy, A Sorolla, E Wang, E Golden, E Woodward, K Davern, D Ho, ... NPJ precision oncology 4 (1), 24, 2020 | 117 | 2020 |
Generation of tumor-initiating cells by exogenous delivery of OCT4transcription factor AS Beltran, AG Rivenbark, BT Richardson, X Yuan, H Quian, JP Hunt, ... Breast cancer research 13, 1-21, 2011 | 114 | 2011 |
Zinc fingers, TALEs, and CRISPR systems: a comparison of tools for epigenome editing CB Waryah, C Moses, M Arooj, P Blancafort Epigenome editing: methods and protocols, 19-63, 2018 | 105 | 2018 |
Gene expression in breastmilk cells is associated with maternal and infant characteristics AJ Twigger, AR Hepworth, C Tat Lai, E Chetwynd, AM Stuebe, ... Scientific reports 5 (1), 12933, 2015 | 105 | 2015 |
Stable oncogenic silencing in vivo by programmable and targeted de novo DNA methylation in breast cancer S Stolzenburg, AS Beltran, T Swift-Scanlan, AG Rivenbark, R Rashwan, ... Oncogene 34 (43), 5427-5435, 2015 | 102 | 2015 |
Novel role of Engrailed 1 as a prosurvival transcription factor in basal-like breast cancer and engineering of interference peptides block its oncogenic function AS Beltran, LM Graves, P Blancafort Oncogene 33 (39), 4767-4777, 2014 | 90 | 2014 |
Activating PTEN tumor suppressor expression with the CRISPR/dCas9 system C Moses, F Nugent, CB Waryah, B Garcia-Bloj, AR Harvey, P Blancafort Molecular Therapy-Nucleic Acids 14, 287-300, 2019 | 86 | 2019 |
Precision medicine by designer interference peptides: applications in oncology and molecular therapeutics A Sorolla, E Wang, E Golden, C Duffy, ST Henriques, AD Redfern, ... Oncogene 39 (6), 1167-1184, 2020 | 85 | 2020 |
Cisplatin induces differentiation of breast cancer cells P Prabhakaran, F Hassiotou, P Blancafort, L Filgueira Frontiers in oncology 3, 134, 2013 | 85 | 2013 |