Triggering of inflammasome by aggregated α–synuclein, an inflammatory response in synucleinopathies G Codolo, N Plotegher, T Pozzobon, M Brucale, I Tessari, L Bubacco, ... PloS one 8 (1), e55375, 2013 | 601 | 2013 |
Kinetic and structural analysis of the early oxidation products of dopamine: Analysis of the interactions with α-synuclein M Bisaglia, S Mammi, L Bubacco Journal of Biological Chemistry 282 (21), 15597-15605, 2007 | 340 | 2007 |
Impaired dopamine metabolism in Parkinson’s disease pathogenesis A Masato, N Plotegher, D Boassa, L Bubacco Molecular neurodegeneration 14 (1), 35, 2019 | 285 | 2019 |
Conformational equilibria in monomeric α-synuclein at the single-molecule level M Sandal, F Valle, I Tessari, S Mammi, E Bergantino, F Musiani, ... PLoS biology 6 (1), e6, 2008 | 241 | 2008 |
Structural insights on physiological functions and pathological effects of±‐synuclein M Bisaglia, S Mammi, L Bubacco The FASEB Journal 23 (2), 329-340, 2009 | 200 | 2009 |
LRRK2 and neuroinflammation: partners in crime in Parkinson’s disease? I Russo, L Bubacco, E Greggio Journal of neuroinflammation 11, 1-9, 2014 | 197 | 2014 |
GTPase activity regulates kinase activity and cellular phenotypes of Parkinson's disease-associated LRRK2 A Biosa, A Trancikova, L Civiero, L Glauser, L Bubacco, E Greggio, ... Human molecular genetics 22 (6), 1140-1156, 2013 | 172 | 2013 |
COVID-19 and possible links with Parkinson’s disease and parkinsonism: from bench to bedside D Sulzer, A Antonini, V Leta, A Nordvig, RJ Smeyne, JE Goldman, ... npj Parkinson's Disease 6 (1), 18, 2020 | 158 | 2020 |
Copper ions and Parkinson’s disease: why is homeostasis so relevant? M Bisaglia, L Bubacco Biomolecules 10 (2), 195, 2020 | 155 | 2020 |
A topological model of the interaction between α-synuclein and sodium dodecyl sulfate micelles M Bisaglia, I Tessari, L Pinato, M Bellanda, S Giraudo, M Fasano, ... Biochemistry 44 (1), 329-339, 2005 | 145 | 2005 |
Tyrosinase exacerbates dopamine toxicity but is not genetically associated with Parkinson's disease E Greggio, E Bergantino, D Carter, R Ahmad, GE Costin, VJ Hearing, ... Journal of neurochemistry 93 (1), 246-256, 2005 | 142 | 2005 |
The reaction of α-synuclein with tyrosinase: Possible implications for Parkinson disease I Tessari, M Bisaglia, F Valle, B Samorì, E Bergantino, S Mammi, ... Journal of Biological Chemistry 283 (24), 16808-16817, 2008 | 141 | 2008 |
DOPAL derived alpha-synuclein oligomers impair synaptic vesicles physiological function N Plotegher, G Berti, E Ferrari, I Tessari, M Zanetti, L Lunelli, E Greggio, ... Scientific reports 7 (1), 40699, 2017 | 139 | 2017 |
Leucine-rich repeat kinase 2 positively regulates inflammation and down-regulates NF-κB p50 signaling in cultured microglia cells I Russo, G Berti, N Plotegher, G Bernardo, R Filograna, L Bubacco, ... Journal of neuroinflammation 12, 1-13, 2015 | 136 | 2015 |
Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimers L Civiero, R Vancraenenbroeck, E Belluzzi, A Beilina, E Lobbestael, ... Public Library of Science 7 (8), e43472, 2012 | 122 | 2012 |
Exosomes-associated neurodegeneration and progression of Parkinson’s disease I Russo, L Bubacco, E Greggio American journal of neurodegenerative disease 1 (3), 217, 2012 | 122 | 2012 |
Alpha-synuclein pore forming activity upon membrane association L Tosatto, AO Andrighetti, N Plotegher, V Antonini, I Tessari, L Ricci, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (11), 2876-2883, 2012 | 114 | 2012 |
Structural and morphological characterization of aggregated species of α-synuclein induced by docosahexaenoic acid G De Franceschi, E Frare, M Pivato, A Relini, A Penco, E Greggio, ... Journal of Biological Chemistry 286 (25), 22262-22274, 2011 | 112 | 2011 |
Dopamine quinones interact with α-synuclein to form unstructured adducts M Bisaglia, L Tosatto, F Munari, I Tessari, PP de Laureto, S Mammi, ... Biochemical and biophysical research communications 394 (2), 424-428, 2010 | 112 | 2010 |
LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex MD Cirnaru, A Marte, E Belluzzi, I Russo, M Gabrielli, F Longo, L Arcuri, ... Frontiers in molecular neuroscience 7, 49, 2014 | 109 | 2014 |