S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding MR Hara, N Agrawal, SF Kim, MB Cascio, M Fujimuro, Y Ozeki, ... Nature cell biology 7 (7), 665-674, 2005 | 1233 | 2005 |
Distinct phosphorylation sites on the β2-adrenergic receptor establish a barcode that encodes differential functions of β-arrestin KN Nobles, K Xiao, S Ahn, AK Shukla, CM Lam, S Rajagopal, ... Science signaling 4 (185), ra51-ra51, 2011 | 698 | 2011 |
Nitric oxide regulates exocytosis by S-nitrosylation of N-ethylmaleimide-sensitive factor K Matsushita, CN Morrell, B Cambien, SX Yang, M Yamakuchi, C Bao, ... Cell 115 (2), 139-150, 2003 | 519 | 2003 |
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1 MR Hara, JJ Kovacs, EJ Whalen, S Rajagopal, RT Strachan, W Grant, ... Nature 477 (7364), 349-353, 2011 | 483 | 2011 |
Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis N Sen, MR Hara, MD Kornberg, MB Cascio, BI Bae, N Shahani, B Thomas, ... Nature cell biology 10 (7), 866-873, 2008 | 447 | 2008 |
GAPDH mediates nitrosylation of nuclear proteins MD Kornberg, N Sen, MR Hara, KR Juluri, JVK Nguyen, AM Snowman, ... Nature cell biology 12 (11), 1094-1100, 2010 | 427 | 2010 |
Cell signaling and neuronal death MR Hara, SH Snyder Annu. Rev. Pharmacol. Toxicol. 47, 117-141, 2007 | 294 | 2007 |
Neuroprotection by pharmacologic blockade of the GAPDH death cascade MR Hara, B Thomas, MB Cascio, BI Bae, LD Hester, VL Dawson, ... Proceedings of the National Academy of Sciences 103 (10), 3887-3889, 2006 | 280 | 2006 |
GAPDH as a sensor of NO stress MR Hara, MB Cascio, A Sawa Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1762 (5), 502-509, 2006 | 263 | 2006 |
Arrestin development: emerging roles for β-arrestins in developmental signaling pathways JJ Kovacs, MR Hara, CL Davenport, J Kim, RJ Lefkowitz Developmental cell 17 (4), 443-458, 2009 | 244 | 2009 |
Nitric oxide–GAPDH–Siah: a novel cell death cascade MR Hara, SH Snyder Cellular and molecular neurobiology 26, 525-536, 2006 | 231 | 2006 |
Global phosphorylation analysis of β-arrestin–mediated signaling downstream of a seven transmembrane receptor (7TMR) K Xiao, J Sun, J Kim, S Rajagopal, B Zhai, J Villén, W Haas, JJ Kovacs, ... Proceedings of the National Academy of Sciences 107 (34), 15299-15304, 2010 | 226 | 2010 |
β-Arrestin-2 mediates anti-apoptotic signaling through regulation of BAD phosphorylation S Ahn, J Kim, MR Hara, XR Ren, RJ Lefkowitz Journal of Biological Chemistry 284 (13), 8855-8865, 2009 | 198 | 2009 |
GOSPEL: a neuroprotective protein that binds to GAPDH upon S-nitrosylation N Sen, MR Hara, AS Ahmad, MB Cascio, A Kamiya, JT Ehmsen, ... Neuron 63 (1), 81-91, 2009 | 157 | 2009 |
Mutant huntingtin: nuclear translocation and cytotoxicity mediated by GAPDH BI Bae, MR Hara, MB Cascio, CL Wellington, MR Hayden, CA Ross, ... Proceedings of the National Academy of Sciences 103 (9), 3405-3409, 2006 | 153 | 2006 |
Pharmacological blockade of a β2AR-β-arrestin-1 signaling cascade prevents the accumulation of DNA damage in a behavioral stress model MR Hara, BD Sachs, MG Caron, RJ Lefkowitz Cell cycle 12 (2), 219-224, 2013 | 98 | 2013 |
β-arrestin1 mediates metastatic growth of breast cancer cells by facilitating HIF-1-dependent VEGF expression SK Shenoy, S Han, YL Zhao, MR Hara, T Oliver, Y Cao, MW Dewhirst Oncogene 31 (3), 282-292, 2012 | 81 | 2012 |
βarrestin-1 regulates DNA repair by acting as an E3-ubiquitin ligase adaptor for 53BP1 A Nieto, MR Hara, V Quereda, W Grant, V Saunders, K Xiao, ... Cell Death & Differentiation 27 (4), 1200-1213, 2020 | 16 | 2020 |
Correction: Global phosphorylation analysis of ß-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR) K Xiao, J Sun, J Kim, S Rajagopal, B Zhai, J Villén, W Haas, JJ Kovacs, ... Proceedings of the National Academy of Sciences of the United States of …, 2012 | | 2012 |