Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo FR Lamont, DC Tomlinson, PA Cooper, SD Shnyder, JD Chester, ... British journal of cancer 104 (1), 75-82, 2011 | 202 | 2011 |
Design, Synthesis, and Biophysical and Biological Evaluation of a Series of Pyrrolobenzodiazepine−Poly(N-methylpyrrole) Conjugates G Wells, CRH Martin, PW Howard, ZA Sands, CA Laughton, A Tiberghien, ... Journal of medicinal chemistry 49 (18), 5442-5461, 2006 | 174 | 2006 |
Fibroblast growth factor receptor 1 promotes proliferation and survival via activation of the mitogen-activated protein kinase pathway in bladder cancer DC Tomlinson, FR Lamont, SD Shnyder, MA Knowles Cancer research 69 (11), 4613-4620, 2009 | 141 | 2009 |
Quantitative Angiogenesis Assays in vivo – A Review J Hasan, SD Shnyder, M Bibby, JA Double, R Bicknel, GC Jayson Angiogenesis 7, 1-16, 2004 | 141 | 2004 |
Organometallic osmium arene complexes with potent cancer cell cytotoxicity Y Fu, A Habtemariam, AM Pizarro, SH van Rijt, DJ Healey, PA Cooper, ... Journal of medicinal chemistry 53 (22), 8192-8196, 2010 | 138 | 2010 |
Synthesis of some cryptolepine analogues, assessment of their antimalarial and cytotoxic activities, and consideration of their antimalarial mode of action O Onyeibor, SL Croft, HI Dodson, M Feiz-Haddad, H Kendrick, ... Journal of medicinal chemistry 48 (7), 2701-2709, 2005 | 137 | 2005 |
Comparative preclinical pharmacokinetic and metabolic studies of the combretastatin prodrugs combretastatin A4 phosphate and A1 phosphate IG Kirwan, PM Loadman, DJ Swaine, DA Anthoney, GR Pettit, ... Clinical Cancer Research 10 (4), 1446-1453, 2004 | 133 | 2004 |
Parallel RNA Interference Screens Identify EGFR Activation as an Escape Mechanism in FGFR3-Mutant Cancer MT Herrera-Abreu, A Pearson, J Campbell, SD Shnyder, MA Knowles, ... Cancer discovery 3 (9), 1058-1071, 2013 | 132 | 2013 |
Non‐invasive molecular imaging for preclinical cancer therapeutic development AC O'farrell, SD Shnyder, G Marston, PL Coletta, JH Gill British journal of pharmacology 169 (4), 719-735, 2013 | 124 | 2013 |
Secretory phospholipase A2 as a tumor-specific trigger for targeted delivery of a novel class of liposomal prodrug anticancer etherlipids SS Jensen, TL Andresen, J Davidsen, P Høyrup, SD Shnyder, MC Bibby, ... Molecular cancer therapeutics 3 (11), 1451-1458, 2004 | 109 | 2004 |
Single-chain TNF, a TNF derivative with enhanced stability and antitumoral activity A Krippner-Heidenreich, I Grunwald, G Zimmermann, M Kühnle, ... The Journal of Immunology 180 (12), 8176-8183, 2008 | 108 | 2008 |
Guaianolide sesquiterpenes from Pulicaria crispa (Forssk.) oliv. M Stavri, KT Mathew, A Gordon, SD Shnyder, RA Falconer, S Gibbons Phytochemistry 69 (9), 1915-1918, 2008 | 93 | 2008 |
Anti-colorectal cancer activity of an organometallic osmium arene azopyridine complex SD Shnyder, Y Fu, A Habtemariam, SH van Rijt, PA Cooper, PM Loadman, ... MedChemComm 2 (7), 666-668, 2011 | 84 | 2011 |
Heparin octasaccharides inhibit angiogenesis in vivo J Hasan, SD Shnyder, AR Clamp, AT McGown, R Bicknell, M Presta, ... Clinical cancer research 11 (22), 8172-8179, 2005 | 83 | 2005 |
Preliminary pharmacokinetic and bioanalytical studies of SJG-136 (NSC 694501), a sequence-selective pyrrolobenzodiazepine dimer DNA-cross-linking agent GP Wilkinson, JP Taylor, S Shnyder, P Cooper, PW Howard, DE Thurston, ... Investigational New Drugs 22, 231-240, 2004 | 82 | 2004 |
Development of a novel tumor-targeted vascular disrupting agent activated by membrane-type matrix metalloproteinases JM Atkinson, RA Falconer, DR Edwards, CJ Pennington, CS Siller, ... Cancer research 70 (17), 6902-6912, 2010 | 76 | 2010 |
ERp29 is a ubiquitous resident of the endoplasmic reticulum with a distinct role in secretory protein production SD Shnyder, MJ Hubbard Journal of Histochemistry & Cytochemistry 50 (4), 557-566, 2002 | 76 | 2002 |
The hollow fibre model-facilitating anti-cancer pre-clinical pharmacodynamics and improving animal welfare M Suggitt, PA Cooper, SD Shnyder, MC Bibby International journal of oncology 29 (6), 1493-1499, 2006 | 75 | 2006 |
RGD-binding integrins in prostate cancer: expression patterns and therapeutic prospects against bone metastasis M Sutherland, A Gordon, SD Shnyder, LH Patterson, HM Sheldrake Cancers 4 (4), 1106-1145, 2012 | 71 | 2012 |
Pharmacological inhibition of polysialyltransferase ST8SiaII modulates tumour cell migration YMJ Al-Saraireh, M Sutherland, BR Springett, F Freiberger, ... PloS one 8 (8), e73366, 2013 | 69 | 2013 |