The Drug Repurposing Hub: a next-generation drug library and information resource SM Corsello, JA Bittker, Z Liu, J Gould, P McCarren, JE Hirschman, ... Nature medicine 23 (4), 405-408, 2017 | 851 | 2017 |
Discovering the anticancer potential of non-oncology drugs by systematic viability profiling SM Corsello, RT Nagari, RD Spangler, J Rossen, M Kocak, JG Bryan, ... Nature cancer 1 (2), 235-248, 2020 | 571 | 2020 |
Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation M Oser, H Yamaguchi, CC Mader, JJ Bravo-Cordero, M Arias, X Chen, ... The Journal of cell biology 186 (4), 571, 2009 | 435 | 2009 |
An EGFR–Src–Arg–cortactin pathway mediates functional maturation of invadopodia and breast cancer cell invasion CC Mader, M Oser, MAO Magalhaes, JJ Bravo-Cordero, J Condeelis, ... Cancer research 71 (5), 1730-1741, 2011 | 346 | 2011 |
Immunomodulatory spherical nucleic acids AF Radovic-Moreno, N Chernyak, CC Mader, S Nallagatla, RS Kang, ... Proceedings of the National Academy of Sciences 112 (13), 3892-3897, 2015 | 293 | 2015 |
Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity GS Kinker, AC Greenwald, R Tal, Z Orlova, MS Cuoco, JM McFarland, ... Nature genetics 52 (11), 1208-1218, 2020 | 287 | 2020 |
Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway MAO Magalhaes, DR Larson, CC Mader, JJ Bravo-Cordero, H Gil-Henn, ... The Journal of cell biology 195 (5), 903, 2011 | 248 | 2011 |
Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodia M Oser, CC Mader, H Gil-Henn, M Magalhaes, JJ Bravo-Cordero, ... Journal of cell science 123 (21), 3662-3673, 2010 | 189 | 2010 |
Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data A Koleti, R Terryn, V Stathias, C Chung, DJ Cooper, JP Turner, D Vidović, ... Nucleic acids research 46 (D1), D558-D566, 2018 | 175 | 2018 |
The vacuolar-ATPase modulates matrix metalloproteinase isoforms in human pancreatic cancer C Chung, CC Mader, JC Schmitz, J Atladottir, P Fitchev, ML Cornwell, ... Laboratory investigation 91 (5), 732-743, 2011 | 140 | 2011 |
Arg interacts with cortactin to promote adhesion-dependent cell edge protrusion S Lapetina, CC Mader, K Machida, BJ Mayer, AJ Koleske The Journal of cell biology 185 (3), 503, 2009 | 120 | 2009 |
Scanning probe-enabled nanocombinatorics define the relationship between fibronectin feature size and stem cell fate LR Giam, MD Massich, L Hao, L Shin Wong, CC Mader, CA Mirkin Proceedings of the National Academy of Sciences 109 (12), 4377-4382, 2012 | 112 | 2012 |
Phosphorylated cortactin recruits Vav2 guanine nucleotide exchange factor to activate Rac3 and promote invadopodial function in invasive breast cancer cells BJ Rosenberg, H Gil-Henn, CC Mader, T Halo, T Yin, J Condeelis, ... Molecular biology of the cell 28 (10), 1347-1360, 2017 | 47 | 2017 |
Lessons learned from SARS-CoV-2 measurements in wastewater ME Sharkey, N Kumar, AMA Mantero, KM Babler, MM Boone, ... Science of The Total Environment 798, 149177, 2021 | 43 | 2021 |
Amphiastral mitotic spindle assembly in vertebrate cells lacking centrosomes JE Hornick, CC Mader, EK Tribble, CC Bagne, KT Vaughan, SL Shaw, ... Current Biology 21 (7), 598-605, 2011 | 42 | 2011 |
Non-oncology drugs are a source of previously unappreciated anti-cancer activity SM Corsello, RT Nagari, RD Spangler, J Rossen, M Kocak, JG Bryan, ... BioRxiv, 730119, 2019 | 38 | 2019 |
Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use AF Radovic-Moreno, CC Mader, S Nallagatla, W Hasan, A Love, ... US Patent 10,894,963, 2021 | 33 | 2021 |
Liposomal particles, methods of making same and uses thereof CA Mirkin, ST Nguyen, RS Banga, N Chernyak, S Gryaznov, ... US Patent 10,182,988, 2019 | 24 | 2019 |
Spherical nucleic acid-based constructs as immunoregulatory agents S Gryaznov, CC Mader, AF Radovic-Moreno | 23 | 2015 |
Probing cell shape regulation with patterned substratum: requirement of myosin II-mediated contractility CC Mader, EH Hinchcliffe, Y Wang Soft Matter 3 (3), 357-363, 2007 | 20 | 2007 |