UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes YM Kim, MM Brinkmann, ME Paquet, HL Ploegh Nature 452 (7184), 234-238, 2008 | 837 | 2008 |
Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9 B Park, MM Brinkmann, E Spooner, CC Lee, YM Kim, HL Ploegh Nature immunology 9 (12), 1407-1414, 2008 | 585 | 2008 |
The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling MM Brinkmann, E Spooner, K Hoebe, B Beutler, HL Ploegh, YM Kim The Journal of cell biology 177 (2), 265-275, 2007 | 557 | 2007 |
Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes J Henault, J Martinez, JM Riggs, J Tian, P Mehta, L Clarke, M Sasai, ... Immunity 37 (6), 986-997, 2012 | 366 | 2012 |
Granulin is a soluble cofactor for toll-like receptor 9 signaling B Park, L Buti, S Lee, T Matsuwaki, E Spooner, MM Brinkmann, ... Immunity 34 (4), 505-513, 2011 | 223 | 2011 |
Kaposi's Sarcoma-Associated Herpesvirus LANA-1 Interacts with the Short Variant of BRD4 and Releases Cells from a BRD4- and BRD2/RING3-Induced G1 Cell … M Ottinger, T Christalla, K Nathan, MM Brinkmann, A Viejo-Borbolla, ... Journal of virology 80 (21), 10772-10786, 2006 | 184 | 2006 |
Activation of mitogen-activated protein kinase and NF-κB pathways by a Kaposi's sarcoma-associated herpesvirus K15 membrane protein MM Brinkmann, M Glenn, L Rainbow, A Kieser, C Henke-Gendo, ... Journal of virology 77 (17), 9346-9358, 2003 | 171 | 2003 |
Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGAS G Zhang, B Chan, N Samarina, B Abere, M Weidner-Glunde, A Buch, ... Proceedings of the National Academy of Sciences 113 (8), E1034-E1043, 2016 | 162 | 2016 |
SARS‐CoV‐2 outbreak investigation in a German meat processing plant T Günther, M Czech‐Sioli, D Indenbirken, A Robitaille, P Tenhaken, ... EMBO molecular medicine 12 (12), e13296, 2020 | 153 | 2020 |
Regulation of intracellular signalling by the terminal membrane proteins of members of the Gammaherpesvirinae MM Brinkmann, TF Schulz Journal of general virology 87 (5), 1047-1074, 2006 | 144 | 2006 |
Murine B cell response to TLR7 ligands depends on an IFN-β feedback loop NM Green, A Laws, K Kiefer, L Busconi, YM Kim, MM Brinkmann, EH Trail, ... The Journal of Immunology 183 (3), 1569-1576, 2009 | 134 | 2009 |
An action plan for pan-European defence against new SARS-CoV-2 variants V Priesemann, R Balling, MM Brinkmann, S Ciesek, T Czypionka, ... The Lancet 397 (10273), 469-470, 2021 | 124 | 2021 |
The chaperone UNC93B1 regulates Toll-like receptor stability independently of endosomal TLR transport K Pelka, D Bertheloot, E Reimer, K Phulphagar, SV Schmidt, A Christ, ... Immunity 48 (5), 911-922. e7, 2018 | 120 | 2018 |
Viral mediated redirection of NEMO/IKKγ to autophagosomes curtails the inflammatory cascade PM Fliss, TP Jowers, MM Brinkmann, B Holstermann, C Mack, ... PLoS pathogens 8 (2), e1002517, 2012 | 107 | 2012 |
Modulation of host gene expression by the K15 protein of Kaposi's sarcoma-associated herpesvirus MM Brinkmann, M Pietrek, O Dittrich-Breiholz, M Kracht, TF Schulz Journal of virology 81 (1), 42-58, 2007 | 100 | 2007 |
The herpesviral antagonist m152 reveals differential activation of STING‐dependent IRF and NF‐κB signaling and STING's dual role during MCMV infection M Stempel, B Chan, V Juranić Lisnić, A Krmpotić, J Hartung, SR Paludan, ... The EMBO Journal 38 (5), e100983, 2019 | 92 | 2019 |
Calling for pan-European commitment for rapid and sustained reduction in SARS-CoV-2 infections V Priesemann, MM Brinkmann, S Ciesek, S Cuschieri, T Czypionka, ... The lancet 397 (10269), 92-93, 2021 | 88 | 2021 |
Age-Dependent Enterocyte Invasion and Microcolony Formation by Salmonella K Zhang, A Dupont, N Torow, F Gohde, S Leschner, S Lienenklaus, ... PLoS pathogens 10 (9), e1004385, 2014 | 86 | 2014 |
Investigation of a superspreading event preceding the largest meat processing plant-related SARS-Coronavirus 2 outbreak in Germany T Guenther, M Czech-Sioli, D Indenbirken, A Robitailles, P Tenhaken, ... Available at SSRN 3654517, 2020 | 80 | 2020 |
Coevolution pays off: Herpesviruses have the license to escape the DNA sensing pathway M Stempel, B Chan, MM Brinkmann Medical Microbiology and Immunology 208 (3), 495-512, 2019 | 68 | 2019 |