Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets F Tang, D Xu, S Wang, CK Wong, A Martinez-Fundichely, CJ Lee, ... Science 376 (6596), eabe1505, 2022 | 117 | 2022 |
Archaic Hominin Introgression in Africa Contributes to Functional Salivary MUC7 Genetic Variation D Xu, P Pavlidis, RO Taskent, N Alachiotis, C Flanagan, M DeGiorgio, ... Molecular Biology and Evolution 34 (10), 2704-2715, 2017 | 73 | 2017 |
Functional specialization of human salivary glands and origins of proteins intrinsic to human saliva M Saitou, EA Gaylord, E Xu, AJ May, L Neznanova, S Nathan, A Grawe, ... Cell reports 33 (7), 2020 | 72 | 2020 |
Atopic Dermatitis Susceptibility Variants in Filaggrin Hitchhike Hornerin Selective Sweep M Eaaswarkhanth, D Xu, C Flanagan, M Rzhetskaya, MG Hayes, ... Genome biology and evolution 8 (10), 3240-3255, 2016 | 45 | 2016 |
Recent evolution of the salivary mucin MUC7 D Xu, P Pavlidis, S Thamadilok, E Redwood, S Fox, R Blekhman, S Ruhl, ... Scientific reports 6 (1), 31791, 2016 | 38 | 2016 |
The psoriasis-associated deletion of late cornified envelope genes LCE3B and LCE3C has been maintained under balancing selection since Human Denisovan … P Pajic, YL Lin, D Xu, O Gokcumen BMC evolutionary biology 16, 1-7, 2016 | 36 | 2016 |
Evolution and protein interactions of AP2 proteins in Brassicaceae: Evidence linking development and environmental responses L Zeng, Y Yin, C You, Q Pan, D Xu, T Jin, B Zhang, H Ma Journal of integrative plant biology 58 (6), 549-563, 2016 | 20 | 2016 |
VCFtoTree: a user-friendly tool to construct locus-specific alignments and phylogenies from thousands of anthropologically relevant genome sequences D Xu, Y Jaber, P Pavlidis, O Gokcumen BMC bioinformatics 18, 1-8, 2017 | 16 | 2017 |
Loss-of-function tolerance of enhancers in the human genome D Xu, O Gokcumen, E Khurana PLoS Genetics 16 (4), e1008663, 2020 | 13 | 2020 |
Discovery of novel therapeutic targets in cancer using patient-specific gene regulatory networks AN Forbes Weill Medical College of Cornell University, 2022 | 5 | 2022 |
Recapitulation of patient-specific 3D chromatin conformation using machine learning D Xu, AN Forbes, S Cohen, A Palladino, T Karadimitriou, E Khurana Cell reports methods 3 (9), 2023 | 3 | 2023 |
Recapitulation of patient-specific 3D chromatin conformation using machine learning and validation of identified enhancer-gene targets D Xu, AN Forbes, S Cohen, A Palladino, T Karadimitriou, E Khurana bioRxiv, 2021.11. 16.468857, 2021 | 3 | 2021 |
Structural variants in ancient genomes SD Resendez, JR Bradley, D Xu, O Gokcumen Paleogenomics: Genome-scale analysis of ancient DNA, 375-391, 2019 | 3 | 2019 |
A candidate causal variant underlying both enhanced cognitive performance and increased risk of bipolar disorder SQ Shen, JS Kim-Han, L Cheng, D Xu, O Gokcumen, AEO Hughes, ... Biorxiv, 580258, 2019 | 1 | 2019 |
Discovery of novel therapeutic targets using 3D chromatin conformation and patient-specific gene regulatory networks AN Forbes, D Xu, S Cohen, A Palladino, P Pancholi, E Khurana Cancer Research 83 (7_Supplement), 2034-2034, 2023 | | 2023 |
Abstract NG10: Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets F Tang, D Xu, S Wang, CK Wong, A Martinez-Fundichely, CJ Lee, ... Cancer Research 83 (7_Supplement), NG10-NG10, 2023 | | 2023 |
Abstract B026: Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets F Tang, D Xu, S Wang, CK Wong, A Martinez-Fundichely, C Lee, S Cohen, ... Cancer Research 82 (23_Supplement_2), B026-B026, 2022 | | 2022 |
Identifying potential drug targets using patient-derived, tissue specific, gene regulatory networks AN Forbes, D Xu, E Khurana Cancer Research 81 (13_Supplement), 235-235, 2021 | | 2021 |
Patient-specific enhancer-gene networks for hundreds of primary cancer samples D Xu, AN Forbes, S Cohen, A Palladino, T Karadimitriou, E Khurana Cancer Research 81 (13_Supplement), 2034-2034, 2021 | | 2021 |
Assessing regulatory network rewiring in cancer patients using chromatin accessibility profiles A Forbes, D Xu, EK Khurana Cancer Research 80 (16_Supplement), 2478-2478, 2020 | | 2020 |