Optimizing protein stability in vivo L Foit, GJ Morgan, MJ Kern, LR Steimer, AA von Hacht, J Titchmarsh, ... Molecular cell 36 (5), 861-871, 2009 | 186 | 2009 |
Beta-2-glycoprotein I dependent lupus anticoagulants form stable bivalent antibody beta-2-glycoprotein I complexes on phospholipid surfaces J Arnout, C Wittevrongel, M Vanrusselt, M Hoylaerts, J Vermylen Thrombosis and haemostasis 59 (01), 79-86, 1998 | 126 | 1998 |
Intravenous immunoglobulin, splenectomy, and antibiotic prophylaxis in Wiskott-Aldrich syndrome. J Litzman, A Jones, I Hann, H Chapel, S Strobel, G Morgan Archives of disease in childhood 75 (5), 436-439, 1996 | 121 | 1996 |
Essential role of proline isomerization in stefin B tetramer formation SJ Kokalj, G Gunčar, I Štern, G Morgan, S Rabzelj, M Kenig, RA Staniforth, ... Journal of molecular biology 366 (5), 1569-1579, 2007 | 101 | 2007 |
Unfolded protein response activation reduces secretion and extracellular aggregation of amyloidogenic immunoglobulin light chain CB Cooley, LM Ryno, L Plate, GJ Morgan, JD Hulleman, JW Kelly, ... Proceedings of the National Academy of Sciences 111 (36), 13046-13051, 2014 | 96 | 2014 |
Transforming a hospital through growing, not building, an electronic patient record system CJ Atkinson, VJ Peel Methods of information in medicine 37 (03), 285-293, 1998 | 93 | 1998 |
Demonstration of induction of erythrocyte inosine monophosphate dehydrogenase activity in Ribavirin-treated patients using a high performance liquid chromatography linked method C Montero, JA Duley, LD Fairbanks, MB McBride, V Micheli, AJ Cant, ... Clinica chimica acta 238 (2), 169-178, 1995 | 87 | 1995 |
The kinetic stability of a full-length antibody light chain dimer determines whether endoproteolysis can release amyloidogenic variable domains GJ Morgan, JW Kelly Journal of molecular biology 428 (21), 4280-4297, 2016 | 86 | 2016 |
Central nervous system dysfunction and erythrocyte guanosine triphosphate depletion in purine nucleoside phosphorylase deficiency. HA Simmonds, LD Fairbanks, GS Morris, G Morgan, AR Watson, P Timms, ... Archives of disease in childhood 62 (4), 385-391, 1987 | 78 | 1987 |
Unexpected and variable phenotypes in a family with JAK3 deficiency DM Frucht, M Gadina, GJ Jagadeesh, I Aksentijevich, K Takada, ... Genes & Immunity 2 (8), 422-432, 2001 | 73 | 2001 |
Stabilization of amyloidogenic immunoglobulin light chains by small molecules GJ Morgan, NL Yan, DE Mortenson, E Rennella, JM Blundon, RM Gwin, ... Proceedings of the National Academy of Sciences 116 (17), 8360-8369, 2019 | 66 | 2019 |
Isoprinosine does not protect against frequent respiratory tract infections in childhood J Litzman, J Lokaj, M Krejčí, S Pešák, G Morgan European journal of pediatrics 158, 32-37, 1999 | 59 | 1999 |
Role of domain interactions in the aggregation of full-length immunoglobulin light chains E Rennella, GJ Morgan, JW Kelly, LE Kay Proceedings of the National Academy of Sciences 116 (3), 854-863, 2019 | 58 | 2019 |
Early VEP and ERG evidence of visual dysfunction in autosomal recessive osteopetrosis DA Thompson, A Kriss, D Taylor, I Russell-Eggitt, P Hodgkins, G Morgan, ... Neuropediatrics 29 (03), 137-144, 1998 | 55 | 1998 |
Reticular dysgenesis: HLA non-identical bone marrow transplants in a series of 10 patients Y Bertrand, SM Müller, JL Casanova, G Morgan, A Fischer, W Friedrich Bone marrow transplantation 29 (9), 759-762, 2002 | 50 | 2002 |
Transient disorder along pathways to amyloid GJ Morgan Biophysical Chemistry 281, 106711, 2022 | 42 | 2022 |
Conformational properties of the unfolded state of Im7 in nondenaturing conditions CL Pashley, GJ Morgan, AP Kalverda, GS Thompson, C Kleanthous, ... Journal of molecular biology 416 (2), 300-318, 2012 | 42 | 2012 |
Differential sensitivity of target genes to translational repression by miR-17~ 92 HY Jin, H Oda, P Chen, C Yang, X Zhou, SG Kang, E Valentine, ... PLoS genetics 13 (2), e1006623, 2017 | 39 | 2017 |
Exclusion of the native α-helix from the amyloid fibrils of a mixed α/β protein GJ Morgan, S Giannini, AM Hounslow, CJ Craven, E Zerovnik, V Turk, ... Journal of molecular biology 375 (2), 487-498, 2008 | 39 | 2008 |
Incomplete refolding of antibody light chains to non-native, protease-sensitive conformations leads to aggregation: a mechanism of amyloidogenesis in patients? GJ Morgan, GA Usher, JW Kelly Biochemistry 56 (50), 6597-6614, 2017 | 33 | 2017 |