PCK1 attenuates tumor stemness via activating the Hippo signaling pathway in hepatocellular carcinoma R Liu, Y Liu, W Zhang, G Zhang, Z Zhang, L Huang, N Tang, K Wang Genes & Diseases 11 (4), 101114, 2024 | | 2024 |
Prophylactic efficacy of an intranasal spray with 2 synergetic antibodies neutralizing Omicron X Zhang, F Luo, H Zhang, H Guo, J Zhou, T Li, S Chen, S Song, M Shen, ... JCI insight 9 (7), 2024 | 6* | 2024 |
Inhibiting HMGCR represses stemness and metastasis of hepatocellular carcinoma via Hedgehog signaling Z Zhang, J Yang, R Liu, J Ma, K Wang, X Wang, N Tang Genes & Diseases, 101285, 2024 | | 2024 |
O-GlcNAcylation of E3 ubiquitin ligase SKP2 promotes hepatocellular carcinoma proliferation Z Feng, J Yin, Z Zhang, Z Chen, L Huang, N Tang, K Wang Oncogene, 1-11, 2024 | | 2024 |
Metabolic Enzyme SLC27A5 Regulates PIP4K2A pre‐mRNA Splicing as a Noncanonical Mechanism to Suppress Hepatocellular Carcinoma Metastasis D Nie, X Tang, H Deng, X Yang, J Tao, F Xu, Y Liu, K Wu, K Wang, Z Mei, ... Advanced Science 11 (5), 2305374, 2024 | | 2024 |
SPOP promotes CREB5 ubiquitination to inhibit MET signaling in liver cancer D Gong, P Zhou, W Chang, J Yang, Y Zhang, A Huang, N Tang, K Wang Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1871 (2), 119642, 2024 | | 2024 |
EGR1 suppresses HCC growth and aerobic glycolysis by transcriptionally downregulating PFKL M Pan, M Luo, L Liu, Y Chen, Z Cheng, K Wang, L Huang, N Tang, J Qiu, ... Journal of Experimental & Clinical Cancer Research 43 (1), 35, 2024 | 1 | 2024 |
Loss of SLC27A5 Activates Hepatic Stellate Cells and Promotes Liver Fibrosis via Unconjugated Cholic Acid K Wu, Y Liu, J Xia, J Liu, K Wang, H Liang, F Xu, D Liu, D Nie, X Tang, ... Advanced Science 11 (2), 2304408, 2024 | 1 | 2024 |
Signaling Metabolite Succinylacetone Activates HIF-1α and Promotes Angiogenesis in GSTZ1-Deficient Hepatocellular Carcinoma H Luo, Q Wang, F Yang, R Liu, Q Gao, B Cheng, X Lin, L Huang, C Chen, ... JCI Insight 8 (23), 164968, 2023 | | 2023 |
SPOP inhibits HBV transcription and replication by ubiquitination and degradation of HNF1α Y Pi, Y Li, Q Yan, H Luo, P Zhou, W Chang, D Gong, Y Hu, K Wang, ... Journal of Medical Virology 95 (12), e29254, 2023 | 1 | 2023 |
High dietary fructose promotes hepatocellular carcinoma progression by enhancing O-GlcNAcylation via microbiota-derived acetate P Zhou, W Chang, D Gong, J Xia, W Chen, L Huang, R Liu, Y Liu, C Chen, ... Cell Metabolism 35 (11), 1961-1975. e6, 2023 | 9 | 2023 |
Identification of a diketopiperazine‐based O‐GlcNAc transferase inhibitor sensitizing hepatocellular carcinoma to CDK9 inhibition X Shan, R Jiang, D Gou, J Xiang, P Zhou, J Xia, K Wang, A Huang, ... The FEBS Journal 290 (18), 4543-4561, 2023 | 2 | 2023 |
Gluconeogenic enzyme PCK1 supports S-adenosylmethionine biosynthesis and promotes H3K9me3 modification to suppress hepatocellular carcinoma progression D Gou, R Liu, X Shan, H Deng, C Chen, J Xiang, Y Liu, Q Gao, Z Li, ... The Journal of Clinical Investigation 133 (13), 2023 | 12 | 2023 |
PLEKHG5 is stabilized by HDAC2-related deacetylation and confers sorafenib resistance in hepatocellular carcinoma Y Sha, M Pan, Y Chen, L Qiao, H Zhou, D Liu, W Zhang, K Wang, ... Cell Death Discovery 9 (1), 176, 2023 | 1 | 2023 |
Deficiency of gluconeogenic enzyme PCK1 promotes metabolic-associated fatty liver disease through PI3K/AKT/PDGF axis activation in male mice Q Ye, Y Liu, G Zhang, H Deng, X Wang, L Tuo, C Chen, X Pan, K Wu, ... Nature Communications 14 (1), 1402, 2023 | 25* | 2023 |
Synthesis and evaluation of N-sulfonylpiperidine-3-carboxamide derivatives as capsid assembly modulators inhibiting HBV in vitro and in HBV-transgenic mice J Yin, Z Feng, Z Li, J Hu, Y Hu, X Cai, H Zhou, K Wang, N Tang, A Huang, ... European Journal of Medicinal Chemistry 249, 115141, 2023 | 3 | 2023 |
O-GlcNAcylation of SPOP promotes carcinogenesis in hepatocellular carcinoma P Zhou, W Chang, D Gong, L Huang, R Liu, Y Liu, J Xia, K Wang, N Tang, ... Oncogene 42 (10), 725-736, 2023 | 9 | 2023 |
O-GlcNAcylation of YTHDF2 promotes HBV-related hepatocellular carcinoma progression in an N6-methyladenosine-dependent manner Y Yang, Y Yan, J Yin, N Tang, K Wang, L Huang, J Hu, Z Feng, Q Gao, ... Signal Transduction and Targeted Therapy 8 (1), 63, 2023 | 38 | 2023 |
SLC27A5 promotes sorafenib-induced ferroptosis in hepatocellular carcinoma by downregulating glutathione reductase F Xu, X Wu, C Chen, K Wang, L Huang, J Xia, Y Liu, X Shan, N Tang Cell Death & Disease 14 (1), 22, 2023 | 22 | 2023 |
PCK1 dysregulation in cancer: Metabolic reprogramming, oncogenic activation, and therapeutic opportunities J Xiang, K Wang, N Tang Genes & Diseases 10 (1), 101-112, 2023 | 8 | 2023 |