Extracellular vesicles: biology and emerging therapeutic opportunities S El Andaloussi, I Mäger, XO Breakefield, MJA Wood Nature reviews Drug discovery 12 (5), 347-357, 2013 | 3091 | 2013 |
Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting OPB Wiklander, JZ Nordin, A O'Loughlin, Y Gustafsson, G Corso, I Mäger, ... Journal of extracellular vesicles 4 (1), 26316, 2015 | 1350 | 2015 |
Cells release subpopulations of exosomes with distinct molecular and biological properties E Willms, HJ Johansson, I Mäger, Y Lee, KEM Blomberg, M Sadik, ... Scientific reports 6 (1), 22519, 2016 | 969 | 2016 |
Methodological guidelines to study extracellular vesicles FAW Coumans, AR Brisson, EI Buzas, F Dignat-George, EEE Drees, ... Circulation research 120 (10), 1632-1648, 2017 | 964 | 2017 |
Extracellular vesicle heterogeneity: subpopulations, isolation techniques, and diverse functions in cancer progression E Willms, C Cabañas, I Mäger, MJA Wood, P Vader Frontiers in immunology 9, 738, 2018 | 850 | 2018 |
Obstacles and opportunities in the functional analysis of extracellular vesicle RNA–an ISEV position paper B Mateescu, EJK Kowal, BWM van Balkom, S Bartel, SN Bhattacharyya, ... Journal of extracellular vesicles 6 (1), 1286095, 2017 | 715 | 2017 |
Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties JZ Nordin, Y Lee, P Vader, I Mäger, HJ Johansson, W Heusermann, ... Nanomedicine: Nanotechnology, Biology and Medicine 11 (4), 879-883, 2015 | 677 | 2015 |
Isolation of exosomes from blood plasma: qualitative and quantitative comparison of ultracentrifugation and size exclusion chromatography methods T Baranyai, K Herczeg, Z Onódi, I Voszka, K Módos, N Marton, G Nagy, ... PloS one 10 (12), e0145686, 2015 | 662 | 2015 |
Exosomes for targeted siRNA delivery across biological barriers SEL Andaloussi, S Lakhal, I Mäger, MJA Wood Advanced drug delivery reviews 65 (3), 391-397, 2013 | 546 | 2013 |
Extracellular vesicles in neurodegenerative disease—pathogenesis to biomarkers AG Thompson, E Gray, SM Heman-Ackah, I Mäger, K Talbot, ... Nature Reviews Neurology 12 (6), 346-357, 2016 | 358 | 2016 |
Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo S El Andaloussi, T Lehto, I Mäger, K Rosenthal-Aizman, II Oprea, ... Nucleic acids research 39 (9), 3972-3987, 2011 | 331 | 2011 |
Reproducible and scalable purification of extracellular vesicles using combined bind-elute and size exclusion chromatography G Corso, I Mäger, Y Lee, A Görgens, J Bultema, B Giebel, MJA Wood, ... Scientific reports 7 (1), 11561, 2017 | 213 | 2017 |
Therapeutic potential of multipotent mesenchymal stromal cells and their extracellular vesicles N Heldring, I Mäger, MJA Wood, K Le Blanc, SEL Andaloussi Human gene therapy 26 (8), 506-517, 2015 | 206 | 2015 |
Functional delivery of lipid-conjugated siRNA by extracellular vesicles AJ O’Loughlin, I Mäger, OG de Jong, MA Varela, RM Schiffelers, ... Molecular Therapy 25 (7), 1580-1587, 2017 | 192 | 2017 |
In vivo biodistribution and efficacy of peptide mediated delivery P Järver, I Mäger, Ü Langel Trends in pharmacological sciences 31 (11), 528-535, 2010 | 179 | 2010 |
C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia Y Aoki, R Manzano, Y Lee, R Dafinca, M Aoki, AGL Douglas, MA Varela, ... Brain 140 (4), 887-897, 2017 | 178 | 2017 |
Serum-free culture alters the quantity and protein composition of neuroblastoma-derived extracellular vesicles J Li, Y Lee, HJ Johansson, I Mäger, P Vader, JZ Nordin, OPB Wiklander, ... Journal of extracellular vesicles 4 (1), 26883, 2015 | 178 | 2015 |
Delivery of nucleic acids with a stearylated (RxR) 4 peptide using a non-covalent co-incubation strategy T Lehto, R Abes, N Oskolkov, J Suhorutšenko, DM Copolovici, I Mäger, ... Journal of Controlled Release 141 (1), 42-51, 2010 | 151 | 2010 |
Sensitive and rapid detection of Chlamydia trachomatis by recombinase polymerase amplification directly from urine samples K Krõlov, J Frolova, O Tudoran, J Suhorutsenko, T Lehto, H Sibul, I Mäger, ... The Journal of Molecular Diagnostics 16 (1), 127-135, 2014 | 150 | 2014 |
A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA OG de Jong, DE Murphy, I Mäger, E Willms, A Garcia-Guerra, ... Nature communications 11 (1), 1113, 2020 | 138 | 2020 |