| A calcium-induced signaling cascade leading to osteogenic differentiation of human bone marrow-derived mesenchymal stromal cells AMC Barradas, HAM Fernandes, N Groen, YC Chai, J Schrooten, ... Biomaterials 33 (11), 3205-3215, 2012 | 462 | 2012 |
| Life-course genome-wide association study meta-analysis of total body BMD and assessment of age-specific effects C Medina-Gomez, JP Kemp, K Trajanoska, J Luan, A Chesi, TS Ahluwalia, ... The American Journal of Human Genetics 102 (1), 88-102, 2018 | 305 | 2018 |
| Mediator expression profiling epistasis reveals a signal transduction pathway with antagonistic submodules and highly specific downstream targets J van de Peppel, N Kettelarij, H van Bakel, TTJP Kockelkorn, ... Molecular cell 19 (4), 511-522, 2005 | 269 | 2005 |
| MicroRNA functions in osteogenesis and dysfunctions in osteoporosis AJ Van Wijnen, J Van De Peppel, JP Van Leeuwen, JB Lian, GS Stein, ... Current osteoporosis reports 11, 72-82, 2013 | 246 | 2013 |
| Monitoring global messenger RNA changes in externally controlled microarray experiments J van de Peppel, P Kemmeren, H van Bakel, M Radonjic, D van Leenen, ... EMBO reports 4 (4), 387-393, 2003 | 231 | 2003 |
| Genome-wide location of the coactivator mediator: Binding without activation and transient Cdk8 interaction on DNA JC Andrau, L van de Pasch, P Lijnzaad, T Bijma, MG Koerkamp, ... Molecular cell 22 (2), 179-192, 2006 | 201 | 2006 |
| Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course M Graff, JS Ngwa, T Workalemahu, G Homuth, S Schipf, A Teumer, ... Human molecular genetics 22 (17), 3597-3607, 2013 | 163 | 2013 |
| Vitamin D and gene networks in human osteoblasts J van de Peppel, JPTM van Leeuwen Frontiers in Physiology 5, 137, 2014 | 162 | 2014 |
| Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment JP Kemp, C Medina-Gomez, K Estrada, B St Pourcain, DHM Heppe, ... PLoS genetics 10 (6), e1004423, 2014 | 160 | 2014 |
| Calcifying vascular smooth muscle cells and osteoblasts: independent cell types exhibiting extracellular matrix and biomineralization-related mimicries RDAM Alves, M Eijken, J van de Peppel, JPTM van Leeuwen BMC genomics 15, 1-14, 2014 | 107 | 2014 |
| Connectivity Map-based discovery of parbendazole reveals targetable human osteogenic pathway AM Brum, J van de Peppel, CS Van Der Leije, M Schreuders-Koedam, ... Proceedings of the National Academy of Sciences 112 (41), 12711-12716, 2015 | 99 | 2015 |
| A new concept underlying stem cell lineage skewing that explains the detrimental effects of thiazolidinediones on bone C Bruedigam, M Eijken, M Koedam, J Van De Peppel, K Drabek, H Chiba, ... Stem cells 28 (5), 916-927, 2010 | 97 | 2010 |
| Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus C Medina-Gomez, JP Kemp, NL Dimou, E Kreiner, A Chesi, BS Zemel, ... Nature communications 8 (1), 121, 2017 | 85 | 2017 |
| Identification of three early phases of cell-fate determination during osteogenic and adipogenic differentiation by transcription factor dynamics J van de Peppel, T Strini, J Tilburg, H Westerhoff, AJ van Wijnen, ... Stem cell reports 8 (4), 947-960, 2017 | 81 | 2017 |
| Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth J Morhayim, J van de Peppel, JAA Demmers, G Kocer, AL Nigg, ... The FASEB Journal 29 (1), 274-285, 2015 | 77 | 2015 |
| Basic techniques in human mesenchymal stem cell cultures: differentiation into osteogenic and adipogenic lineages, genetic perturbations, and phenotypic analyses C Bruedigam, M Driel, M Koedam, J Peppel, BCJ van der Eerden, ... Current protocols in stem cell biology 17 (1), 1H. 3.1-1H. 3.20, 2011 | 68 | 2011 |
| GPM6B regulates osteoblast function and induction of mineralization by controlling cytoskeleton and matrix vesicle release K Drabek, J van de Peppel, M Eijken, JPTM van Leeuwen Journal of Bone and Mineral Research 26 (9), 2045-2051, 2011 | 63 | 2011 |
| Human memory Th17 cell populations change into anti-inflammatory cells with regulatory capacity upon exposure to active vitamin D W Dankers, N Davelaar, JP Van Hamburg, J Van De Peppel, EM Colin, ... Frontiers in immunology 10, 1504, 2019 | 51 | 2019 |
| Pro-osteogenic trophic effects by PKA activation in human mesenchymal stromal cells J Doorn, J van de Peppel, JPTM van Leeuwen, N Groen, ... Biomaterials 32 (26), 6089-6098, 2011 | 48 | 2011 |
| Dynamic adaptation of mesenchymal stem cell physiology upon exposure to surface micropatterns NRM Beijer, ZM Nauryzgaliyeva, EM Arteaga, L Pieuchot, K Anselme, ... Scientific reports 9 (1), 9099, 2019 | 45 | 2019 |
