Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys TK Warren, R Jordan, MK Lo, AS Ray, RL Mackman, V Soloveva, ... Nature 531 (7594), 381-385, 2016 | 1684 | 2016 |
Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and … D Siegel, HC Hui, E Doerffler, MO Clarke, K Chun, L Zhang, S Neville, ... Journal of medicinal chemistry 60 (5), 1648-1661, 2017 | 764 | 2017 |
Transgenic mice overexpressing the β1-adrenergic receptor in adipose tissue are resistant to obesity V Soloveva, RA Graves, MM Rasenick, BM Spiegelman, SR Ross Molecular endocrinology 11 (1), 27-38, 1997 | 156 | 1997 |
Nodal regulates trophoblast differentiation and placental development GT Ma, V Soloveva, SJ Tzeng, LA Lowe, KC Pfendler, PM Iannaccone, ... Developmental biology 236 (1), 124-135, 2001 | 108 | 2001 |
The FDA-approved oral drug nitazoxanide amplifies host antiviral responses and inhibits Ebola virus LD Jasenosky, C Cadena, CE Mire, V Borisevich, V Haridas, S Ranjbar, ... Iscience 19, 1279-1290, 2019 | 97 | 2019 |
Old and new pharmacology: positive allosteric modulation of the α7 nicotinic acetylcholine receptor by the 5-hydroxytryptamine2B/C receptor antagonist SB-206553 (3, 5-dihydro-5 … J Dunlop, T Lock, B Jow, F Sitzia, S Grauer, F Jow, A Kramer, MR Bowlby, ... Journal of Pharmacology and Experimental Therapeutics 328 (3), 766-776, 2009 | 97 | 2009 |
Efficacy of favipiravir (T-705) in nonhuman primates infected with Ebola virus or Marburg virus SL Bixler, TM Bocan, J Wells, KS Wetzel, SA Van Tongeren, L Dong, ... Antiviral Research 151, 97-104, 2018 | 92 | 2018 |
Triterpenoids manipulate a broad range of virus-host fusion via wrapping the HR2 domain prevalent in viral envelopes L Si, K Meng, Z Tian, J Sun, H Li, Z Zhang, V Soloveva, H Li, G Fu, Q Xia, ... Science advances 4 (11), eaau8408, 2018 | 83 | 2018 |
Nucleotide prodrug GS-5734 is a broad-spectrum filovirus inhibitor that provides complete therapeutic protection against the development of Ebola virus disease (EVD) in … T Warren, R Jordan, M Lo, V Soloveva, A Ray, R Bannister, R Mackman, ... Open Forum Infectious Diseases 2 (suppl_1), LB-2, 2015 | 81 | 2015 |
The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines J Luban, RA Sattler, E Mühlberger, JD Graci, L Cao, M Weetall, C Trotta, ... Virus research 292, 198246, 2021 | 72 | 2021 |
Antitumor efficacy profile of PKI-402, a dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor R Mallon, I Hollander, L Feldberg, J Lucas, V Soloveva, A Venkatesan, ... Molecular Cancer Therapeutics 9 (4), 976-984, 2010 | 65 | 2010 |
Differentiation of placental trophoblast giant cells requires downregulation of p53 and Rb V Soloveva, DIH Linzer Placenta 25 (1), 29-36, 2004 | 56 | 2004 |
Identification of agents effective against multiple toxins and viruses by host-oriented cell targeting L Zilbermintz, W Leonardi, SY Jeong, M Sjodt, R McComb, CLC Ho, ... Scientific reports 5 (1), 13476, 2015 | 49 | 2015 |
Intracellular conversion and in vivo dose response of favipiravir (T-705) in rodents infected with Ebola virus SL Bixler, TM Bocan, J Wells, KS Wetzel, SA Van Tongeren, NL Garza, ... Antiviral research 151, 50-54, 2018 | 42 | 2018 |
Discovery of novel small-molecule inhibitors of LIM domain kinase for inhibiting HIV-1 F Yi, J Guo, D Dabbagh, M Spear, S He, K Kehn-Hall, J Fontenot, Y Yin, ... Journal of virology 91 (13), 10.1128/jvi. 02418-16, 2017 | 41 | 2017 |
Ion channel screening J Dunlop, M Bowlby, R Peri, G Tawa, J LaRocque, V Soloveva, J Morin Combinatorial chemistry & high throughput screening 11 (7), 514-522, 2008 | 40 | 2008 |
Flex-nucleoside analogues–novel therapeutics against filoviruses MK Yates, MR Raje, P Chatterjee, CF Spiropoulou, S Bavari, M Flint, ... Bioorganic & medicinal chemistry letters 27 (12), 2800-2802, 2017 | 37 | 2017 |
Selective targeting of virus replication by proton pump inhibitors SM Watanabe, LS Ehrlich, M Strickland, X Li, V Soloveva, AJ Goff, ... Scientific reports 10 (1), 4003, 2020 | 33 | 2020 |
Identification of a coumarin-based antihistamine-like small molecule as an anti-filoviral entry inhibitor H Cheng, A Schafer, V Soloveva, D Gharaibeh, T Kenny, C Retterer, ... Antiviral research 145, 24-32, 2017 | 32 | 2017 |
Enhancing the antiviral potency of ER α-glucosidase inhibitor IHVR-19029 against hemorrhagic fever viruses in vitro and in vivo J Ma, X Zhang, V Soloveva, T Warren, F Guo, S Wu, H Lu, J Guo, Q Su, ... Antiviral research 150, 112-122, 2018 | 31 | 2018 |