Crystal structure of a hypoallergenic isoform of the major birch pollen allergen Bet v 1 and its likely biological function as a plant steroid carrier Z Marković-Housley, M Degano, D Lamba, E von Roepenack-Lahaye, ... Journal of molecular biology 325 (1), 123-133, 2003 | 381 | 2003 |
Structure of human dipeptidyl peptidase I (cathepsin C): exclusion domain added to an endopeptidase framework creates the machine for activation of granular serine proteases D Turk, V Janjić, I Štern, M Podobnik, D Lamba, SW Dahl, C Lauritzen, ... The EMBO journal, 2001 | 320 | 2001 |
Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin. A Van De Locht, D Lamba, M Bauer, R Huber, T Friedrich, B Kröger, ... The EMBO journal 14 (21), 5149-5157, 1995 | 202 | 1995 |
Three‐dimensional structure of a complex of galanthamine (Nivalin®) with acetylcholinesterase from Torpedo californica: Implications for the design of new anti … C Bartolucci, E Perola, C Pilger, G Fels, D Lamba Proteins: structure, function, and bioinformatics 42 (2), 182-191, 2001 | 200 | 2001 |
The Pseudomonas aeruginosa lectin LecB binds to the exopolysaccharide Psl and stabilizes the biofilm matrix. PMR Passos da Silva D, Matwichuk ML, Townsend DO, Reichhardt C, Lamba D ... Nature Communications 10 (1), 2183, 2019 | 189 | 2019 |
Status of the crystallography beamlines at Elettra A Lausi, M Polentarutti, S Onesti, JR Plaisier, E Busetto, G Bais, L Barba, ... The European Physical Journal Plus 130, 1-8, 2015 | 189 | 2015 |
Multitarget drug design strategy: quinone–tacrine hybrids designed to block amyloid-β aggregation and to exert anticholinesterase and antioxidant effects E Nepovimova, E Uliassi, J Korabecny, LE Pena-Altamira, S Samez, ... Journal of medicinal chemistry 57 (20), 8576-8589, 2014 | 189 | 2014 |
The 2.3 Å crystal structure of the catalytic domain of recombinant two-chain human tissue-type plasminogen activator D Lamba, M Bauer, R Huber, S Fischer, R Rudolph, U Kohnert, W Bode Journal of molecular biology 258 (1), 117-135, 1996 | 161 | 1996 |
Novel tacrine–benzofuran hybrids as potent multitarget-directed ligands for the treatment of Alzheimer’s disease: design, synthesis, biological evaluation, and X-ray … X Zha, D Lamba, L Zhang, Y Lou, C Xu, D Kang, L Chen, Y Xu, L Zhang, ... Journal of Medicinal Chemistry 59 (1), 114-131, 2016 | 142 | 2016 |
“Back door” opening implied by the crystal structure of a carbamoylated acetylcholinesterase C Bartolucci, E Perola, L Cellai, M Brufani, D Lamba Biochemistry 38 (18), 5714-5719, 1999 | 132 | 1999 |
Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease K Chalupova, J Korabecny, M Bartolini, B Monti, D Lamba, R Caliandro, ... European journal of medicinal chemistry 168, 491-514, 2019 | 99 | 2019 |
Membrane crystallization of lysozyme: kinetic aspects G Di Profio, E Curcio, A Cassetta, D Lamba, E Drioli Journal of Crystal Growth 257 (3-4), 359-369, 2003 | 98 | 2003 |
Census of solo LuxR genes in prokaryotic genomes S Hudaiberdiev, KS Choudhary, R Vera Alvarez, Z Gelencsér, B Ligeti, ... Frontiers in cellular and infection microbiology 5, 20, 2015 | 96 | 2015 |
Crystal structure of wild-type chaperonin GroEL C Bartolucci, D Lamba, S Grazulis, E Manakova, H Heumann Journal of molecular biology 354 (4), 940-951, 2005 | 88 | 2005 |
Accurate prediction of the bound conformation of galanthamine in the active site of Torpedo californica acetylcholinesterase using molecular docking C Pilger, C Bartolucci, D Lamba, A Tropsha, G Fels Journal of molecular graphics and modelling 19 (3-4), 288-296, 2001 | 85 | 2001 |
Intrinsic structural disorder of mouse proNGF F Paoletti, S Covaceuszach, PV Konarev, S Gonfloni, F Malerba, ... Proteins: Structure, Function, and Bioinformatics 75 (4), 990-1009, 2009 | 77 | 2009 |
Membrane crystallization of lysozyme under forced solution flow E Curcio, S Simone, G Di Profio, E Drioli, A Cassetta, D Lamba Journal of membrane science 257 (1-2), 134-143, 2005 | 76 | 2005 |
Structural and biochemical analysis of the Rv0805 cyclic nucleotide phosphodiesterase from Mycobacterium tuberculosis AR Shenoy, M Capuder, P Draškovič, D Lamba, SS Visweswariah, ... Journal of molecular biology 365 (1), 211-225, 2007 | 72 | 2007 |
Long chain analogs of physostigmine as potential drugs for Alzheimer's disease: new insights into the mechanism of action in the inhibition of acetylcholinesterase E Perola, L Cellai, D Lamba, L Filocamo, M Brufani Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 1997 | 72 | 1997 |
Structural Determinants of Torpedo californica Acetylcholinesterase Inhibition by the Novel and Orally Active Carbamate Based Anti-Alzheimer Drug Ganstigmine … C Bartolucci, M Siotto, E Ghidini, G Amari, PT Bolzoni, M Racchi, G Villetti, ... Journal of medicinal chemistry 49 (17), 5051-5058, 2006 | 68 | 2006 |