Multi-input RNAi-based logic circuit for identification of specific cancer cells Z Xie, L Wroblewska, L Prochazka, R Weiss, Y Benenson Science 333 (6047), 1307-1311, 2011 | 881 | 2011 |
Mammalian synthetic circuits with RNA binding proteins for RNA-only delivery L Wroblewska, T Kitada, K Endo, V Siciliano, B Stillo, H Saito, R Weiss Nature biotechnology 33 (8), 839-841, 2015 | 237 | 2015 |
A platform for rapid prototyping of synthetic gene networks in mammalian cells X Duportet, L Wroblewska, P Guye, Y Li, J Eyquem, J Rieders, T Rimchala, ... Nucleic acids research 42 (21), 13440-13451, 2014 | 168 | 2014 |
A multi-landing pad DNA integration platform for mammalian cell engineering L Gaidukov, L Wroblewska, B Teague, T Nelson, X Zhang, Y Liu, K Jagtap, ... Nucleic acids research 46 (8), 4072-4086, 2018 | 167 | 2018 |
Rapid, modular and reliable construction of complex mammalian gene circuits P Guye, Y Li, L Wroblewska, X Duportet, R Weiss Nucleic acids research 41 (16), e156-e156, 2013 | 109 | 2013 |
A novel Bxb1 integrase RMCE system for high fidelity site‐specific integration of mAb expression cassette in CHO cells MC Inniss, K Bandara, B Jusiak, TK Lu, R Weiss, L Wroblewska, L Zhang Biotechnology and Bioengineering 114 (8), 1837-1846, 2017 | 103 | 2017 |
Systematic transfer of prokaryotic sensors and circuits to mammalian cells BC Stanton, V Siciliano, A Ghodasara, L Wroblewska, K Clancy, ... ACS synthetic biology 3 (12), 880-891, 2014 | 99 | 2014 |
Analysis of TASSER‐based CASP7 protein structure prediction results H Zhou, SB Pandit, SY Lee, J Borreguero, H Chen, L Wroblewska, ... Proteins: Structure, Function, and Bioinformatics 69 (S8), 90-97, 2007 | 83 | 2007 |
Protein model refinement using an optimized physics-based all-atom force field A Jagielska, L Wroblewska, J Skolnick Proceedings of the National Academy of Sciences 105 (24), 8268-8273, 2008 | 79 | 2008 |
Can a physics‐based, all‐atom potential find a protein's native structure among misfolded structures? I. Large scale AMBER benchmarking L Wroblewska, J Skolnick Journal of Computational Chemistry 28 (12), 2059-2066, 2007 | 77 | 2007 |
Mechanical strain promotes oligodendrocyte differentiation by global changes of gene expression A Jagielska, AL Lowe, E Makhija, L Wroblewska, J Guck, RJM Franklin, ... Frontiers in cellular neuroscience 11, 93, 2017 | 73 | 2017 |
Engineering protein-protein devices for multilayered regulation of mRNA translation using orthogonal proteases in mammalian cells F Cella, L Wroblewska, R Weiss, V Siciliano Nature Communications 9 (1), 4392, 2018 | 67 | 2018 |
Engineering modular intracellular protein sensor-actuator devices V Siciliano, B DiAndreth, B Monel, J Beal, J Huh, KL Clayton, ... Nature communications 9 (1), 1881, 2018 | 65 | 2018 |
Development of a physics-based force field for the scoring and refinement of protein models L Wroblewska, A Jagielska, J Skolnick Biophysical journal 94 (8), 3227-3240, 2008 | 46 | 2008 |
A theoretical and experimental 14N NMR study of association of pyridine E Megiel, T Kasprzycka-Guttman, A Jagielska, L Wroblewska Journal of Molecular Structure 569 (1-3), 111-119, 2001 | 35 | 2001 |
A synthetic transcription platform for programmable gene expression in mammalian cells WCW Chen, L Gaidukov, Y Lai, MR Wu, J Cao, MJ Gutbrod, GCG Choi, ... Nature Communications 13 (1), 6167, 2022 | 18 | 2022 |
Fc-GDF15 glyco-engineering and receptor binding affinity optimization for body weight regulation E Fung, L Kang, D Sapashnik, S Benard, A Sievers, Y Liu, G Yan, J Zhou, ... Scientific reports 11 (1), 8921, 2021 | 16 | 2021 |
Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific antibody for the treatment of solid tumors AR Root, G Guntas, M Katragadda, JR Apgar, J Narula, CS Chang, ... MAbs 13 (1), 1850395, 2021 | 12 | 2021 |
Systemic biodistribution and hepatocyte-specific gene editing with CRISPR/Cas9 using hyaluronic acid-based nanoparticles C Francis, L Wroblewska, P Pegman, M Amiji Nanomedicine: Nanotechnology, Biology and Medicine 40, 102488, 2022 | 9 | 2022 |
Multiple input biologic classifier circuits for cells Y Benenson, R Weiss, L Wroblewska, Z Xie US Patent 9,458,509, 2016 | 7 | 2016 |