miR-21 ablation and obeticholic acid ameliorate nonalcoholic steatohepatitis in mice PM Rodrigues, MB Afonso, AL Simão, CC Carvalho, A Trindade, A Duarte, ... Cell death & disease 8 (4), e2748-e2748, 2017 | 126 | 2017 |
Activation of necroptosis in human and experimental cholestasis MB Afonso, PM Rodrigues, AL Simão, D Ofengeim, T Carvalho, ... Cell Death & Disease 7 (9), e2390-e2390, 2016 | 124 | 2016 |
miRNA-21 ablation protects against liver injury and necroptosis in cholestasis MB Afonso, PM Rodrigues, AL Simão, MM Gaspar, T Carvalho, ... Cell Death & Differentiation 25 (5), 857-872, 2018 | 111 | 2018 |
Circulating microRNAs as potential biomarkers in non-alcoholic fatty liver disease and hepatocellular carcinoma MB Afonso, PM Rodrigues, AL Simao, RE Castro Journal of clinical medicine 5 (3), 30, 2016 | 109 | 2016 |
c-Jun N-terminal kinase 1/c-Jun activation of the p53/microRNA 34a/sirtuin 1 pathway contributes to apoptosis induced by deoxycholic acid in rat liver DMS Ferreira, MB Afonso, PM Rodrigues, AL Simão, DM Pereira, ... Molecular and cellular biology 34 (6), 1100-1120, 2014 | 87 | 2014 |
RIPK3 acts as a lipid metabolism regulator contributing to inflammation and carcinogenesis in non-alcoholic fatty liver disease MB Afonso, PM Rodrigues, M Mateus-Pinheiro, AL Simão, MM Gaspar, ... Gut 70 (12), 2359-2372, 2021 | 77 | 2021 |
Revisiting the metabolic syndrome and paving the way for micro RNA s in non‐alcoholic fatty liver disease DMS Ferreira, AL Simão, CMP Rodrigues, RE Castro The FEBS journal 281 (11), 2503-2524, 2014 | 75 | 2014 |
Liquid biopsies in hepatocellular carcinoma: Are we winning? T Mocan, AL Simão, RE Castro, CMP Rodrigues, A Słomka, B Wang, ... Journal of Clinical Medicine 9 (5), 1541, 2020 | 49 | 2020 |
Inhibition of NF-κB by deoxycholic acid induces miR-21/PDCD4-dependent hepatocellular apoptosis PM Rodrigues, MB Afonso, AL Simão, PM Borralho, CMP Rodrigues, ... Scientific reports 5 (1), 17528, 2015 | 38 | 2015 |
Skeletal muscle miR-34a/SIRT1: AMPK axis is activated in experimental and human non-alcoholic steatohepatitis AL Simão, MB Afonso, PM Rodrigues, M Gama-Carvalho, MV Machado, ... Journal of Molecular Medicine 97, 1113-1126, 2019 | 31 | 2019 |
Impact of aging on primary liver cancer: epidemiology, pathogenesis and therapeutics RIR Macias, MJ Monte, MA Serrano, JM González-Santiago, ... Aging (Albany NY) 13 (19), 23416, 2021 | 28 | 2021 |
miR‐21‐5p promotes NASH‐related hepatocarcinogenesis PM Rodrigues, MB Afonso, AL Simão, T Islam, MM Gaspar, CJ O'Rourke, ... Liver International 43 (10), 2256-2274, 2023 | 12 | 2023 |
Cirrhosis is associated with lower serological responses to COVID-19 vaccines in patients with chronic liver disease AL Simão, CS Palma, L Izquierdo-Sanchez, A Putignano, ... JHEP Reports 5 (5), 100697, 2023 | 12 | 2023 |
Isolation of mitochondria from liver and extraction of total RNA and protein: analyses of miRNA and protein expression AL Simão, PM Borralho, CJ Steer, RE Castro, CMP Rodrigues Mitochondrial Regulation: Methods and Protocols, 1-15, 2021 | 5 | 2021 |
Corrigendum: Inhibition of NF-κB by deoxycholic acid induces miR-21/PDCD4-dependent hepatocellular apoptosis PM Rodrigues, MB Afonso, AL Simão, PM Borralho, CMP Rodrigues, ... Scientific Reports 6, 2016 | 5 | 2016 |
The role of necroptosis in non-alcoholic fatty liver disease-related carcinogenesis MB Afonso, PM Rodrigues, AL Simão, AA Santos, MM Gaspar, RE Castro, ... Free Radical Biology and Medicine 120, S33-S34, 2018 | 3 | 2018 |
Anti-miR-873-5p improves alcohol-related liver disease by enhancing hepatic deacetylation via SIRT1 R Rodríguez-Agudo, I González-Recio, M Serrano-Maciá, M Bravo, ... Jhep Reports 6 (1), 100918, 2024 | 2 | 2024 |
Role of mitofusin-2 in NAFLD and targeting by miRNAs A Simão, MB Afonso, P Rodrigues, AJ Amaral, M Gama-Carvalho, ... Journal of Hepatology 68, S356, 2018 | 2 | 2018 |
P0951: MIR-21 inhibition and FXR activation synergistically ameliorate disease pathogenesis in a mouse model of NAFLD PM Rodrigues, MB Afonso, AL Simão, M Caridade, CC Carvalho, ... Journal of Hepatology, S702, 2015 | 2 | 2015 |
mIR-21 is increased in patients with NASH-associated HCC and contributes to hepatocarcinogenesis in mice with NAFLD PM Rodrigues, MB Afonso, A Simão, T Islam, MM Gaspar, CO Rourke, ... Journal of Hepatology 73, S677-S678, 2020 | 1 | 2020 |