High serum levels of extracellular vesicles expressing malignancy-related markers are released in patients with various types of hematological neoplastic disorders A Caivano, I Laurenzana, L De Luca, F La Rocca, V Simeon, S Trino, ... Tumor Biology 36, 9739-9752, 2015 | 188 | 2015 |
MiRNAs and piRNAs from bone marrow mesenchymal stem cell extracellular vesicles induce cell survival and inhibit cell differentiation of cord blood hematopoietic stem cells: a … L De Luca, S Trino, I Laurenzana, V Simeon, G Calice, S Raimondo, ... Oncotarget 7 (6), 6676, 2016 | 110 | 2016 |
MicroRNAs as new biomarkers for diagnosis and prognosis, and as potential therapeutic targets in acute myeloid leukemia S Trino, D Lamorte, A Caivano, I Laurenzana, D Tagliaferri, G Falco, ... International journal of molecular sciences 19 (2), 460, 2018 | 86 | 2018 |
MicroRNA-155 in serum-derived extracellular vesicles as a potential biomarker for hematologic malignancies-a short report A Caivano, F La Rocca, V Simeon, M Girasole, S Dinarelli, I Laurenzana, ... Cellular Oncology 40, 97-103, 2017 | 82 | 2017 |
Dichloroacetate, a selective mitochondria-targeting drug for oral squamous cell carcinoma: a metabolic perspective of treatment V Ruggieri, F Agriesti, R Scrima, I Laurenzana, D Perrone, T Tataranni, ... Oncotarget 6 (2), 1217, 2015 | 69 | 2015 |
Clinical relevance of extracellular vesicles in hematological neoplasms: from liquid biopsy to cell biopsy S Trino, D Lamorte, A Caivano, L De Luca, A Sgambato, I Laurenzana Leukemia 35 (3), 661-678, 2021 | 62 | 2021 |
Dichloroacetate affects mitochondrial function and stemness-associated properties in pancreatic cancer cell lines T Tataranni, F Agriesti, C Pacelli, V Ruggieri, I Laurenzana, C Mazzoccoli, ... Cells 8 (5), 478, 2019 | 58 | 2019 |
Characterization and prognostic relevance of circulating microvesicles in chronic lymphocytic leukemia L De Luca, G D’Arena, V Simeon, S Trino, I Laurenzana, A Caivano, ... Leukemia & lymphoma 58 (6), 1424-1432, 2017 | 56 | 2017 |
Mesenchymal stem cell derived extracellular vesicles: a role in hematopoietic transplantation? L De Luca, S Trino, I Laurenzana, D Lamorte, A Caivano, L Del Vecchio, ... International Journal of Molecular Sciences 18 (5), 1022, 2017 | 51 | 2017 |
Identification of Hck Inhibitors As Hits for the Development of Antileukemia and Anti‐HIV Agents C Tintori, I Laurenzana, F La Rocca, F Falchi, F Carraro, A Ruiz, JA Esté, ... ChemMedChem 8 (8), 1353-1360, 2013 | 51 | 2013 |
Design, Synthesis, and Biological Evaluation of Pyrazolo[3,4-d]pyrimidines Active in Vivo on the Bcr-Abl T315I Mutant M Radi, C Tintori, F Musumeci, C Brullo, C Zamperini, E Dreassi, ... Journal of Medicinal Chemistry 56 (13), 5382-5394, 2013 | 49 | 2013 |
Knockdown of miR-128a induces Lin28a expression and reverts myeloid differentiation blockage in acute myeloid leukemia L De Luca, S Trino, I Laurenzana, D Tagliaferri, G Falco, V Grieco, ... Cell death & disease 8 (6), e2849-e2849, 2017 | 43 | 2017 |
Extracellular vesicles in hematological malignancies: from biology to therapy A Caivano, F La Rocca, I Laurenzana, S Trino, L De Luca, D Lamorte, ... International Journal of Molecular Sciences 18 (6), 1183, 2017 | 41 | 2017 |
Extracellular vesicles: a new prospective in crosstalk between microenvironment and stem cells in hematological malignancies I Laurenzana, D Lamorte, S Trino, L De Luca, C Ambrosino, P Zoppoli, ... Stem cells international 2018 (1), 9863194, 2018 | 40 | 2018 |
The fight against the influenza A virus H1N1: synthesis, molecular modeling, and biological evaluation of benzofurazan derivatives as viral RNA polymerase inhibitors M Pagano, D Castagnolo, M Bernardini, AL Fallacara, I Laurenzana, ... ChemMedChem 9 (1), 129-150, 2014 | 39 | 2014 |
Studies on the ATP binding site of Fyn kinase for the identification of new inhibitors and their evaluation as potential agents against tauopathies and tumors C Tintori, G La Sala, G Vignaroli, L Botta, AL Fallacara, F Falchi, M Radi, ... Journal of Medicinal Chemistry 58 (11), 4590-4609, 2015 | 38 | 2015 |
The iron chelator deferasirox affects redox signalling in haematopoietic stem/progenitor cells T Tataranni, F Agriesti, C Mazzoccoli, V Ruggieri, R Scrima, I Laurenzana, ... British journal of haematology 170 (2), 236-246, 2015 | 36 | 2015 |
High-throughput docking for the identification of new influenza A virus polymerase inhibitors targeting the PA–PB1 protein–protein interaction C Tintori, I Laurenzana, AL Fallacara, U Kessler, B Pilger, L Stergiou, ... Bioorganic & Medicinal Chemistry Letters 24 (1), 280-282, 2014 | 36 | 2014 |
P53-MDM2 pathway: Evidences for a new targeted therapeutic approach in B-acute lymphoblastic leukemia S Trino, L De Luca, I Laurenzana, A Caivano, L Del Vecchio, G Martinelli, ... Frontiers in Pharmacology 7, 491, 2016 | 35 | 2016 |
Targeting the p53-MDM2 interaction by the small-molecule MDM2 antagonist Nutlin-3a: a new challenged target therapy in adult Philadelphia positive acute lymphoblastic leukemia … S Trino, I Iacobucci, D Erriquez, I Laurenzana, L De Luca, A Ferrari, ... Oncotarget 7 (11), 12951, 2016 | 33 | 2016 |