Pharmacogenomics in diabetes mellitus: insights into drug action and drug discovery K Zhou, HK Pedersen, AY Dawed, ER Pearson Nature Reviews Endocrinology 12 (6), 337-346, 2016 | 74 | 2016 |
Heterogeneity in phenotype, disease progression and drug response in type 2 diabetes ATN Nair, A Wesolowska-Andersen, C Brorsson, AL Rajendrakumar, ... Nature Medicine 28 (5), 982-988, 2022 | 70 | 2022 |
CYP2C8 and SLCO1B1 variants and therapeutic response to thiazolidinediones in patients with type 2 diabetes AY Dawed, L Donnelly, R Tavendale, F Carr, G Leese, CNA Palmer, ... Diabetes care 39 (11), 1902-1908, 2016 | 68 | 2016 |
Sustained influence of metformin therapy on circulating glucagon‐like peptide‐1 levels in individuals with and without type 2 diabetes D Preiss, A Dawed, P Welsh, A Heggie, AG Jones, J Dekker, R Koivula, ... Diabetes, Obesity and Metabolism 19 (3), 356-363, 2017 | 67 | 2017 |
Variation in the plasma membrane monoamine transporter (PMAT)(encoded by SLC29A4) and organic cation transporter 1 (OCT1)(encoded by SLC22A1) and gastrointestinal intolerance … AY Dawed, K Zhou, N van Leeuwen, A Mahajan, N Robertson, R Koivula, ... Diabetes Care 42 (6), 1027-1033, 2019 | 65 | 2019 |
Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts N Atabaki-Pasdar, M Ohlsson, A Viñuela, F Frau, H Pomares-Millan, ... PLoS medicine 17 (6), e1003149, 2020 | 60 | 2020 |
Efficacy of modern diabetes treatments DPP-4i, SGLT-2i, and GLP-1RA in white and Asian patients with diabetes: a systematic review and meta-analysis of randomized controlled trials S Gan, AY Dawed, LA Donnelly, ATN Nair, CNA Palmer, V Mohan, ... Diabetes Care 43 (8), 1948-1957, 2020 | 59 | 2020 |
Pharmacogenetics in type 2 diabetes: influence on response to oral hypoglycemic agents AY Dawed, K Zhou, ER Pearson Pharmacogenomics and personalized medicine, 17-29, 2016 | 51 | 2016 |
Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine DK Tobias, J Merino, A Ahmad, C Aiken, JL Benham, D Bodhini, AL Clark, ... Nature medicine 29 (10), 2438-2457, 2023 | 49 | 2023 |
Young-onset diabetes in Asian Indians is associated with lower measured and genetically determined beta cell function MK Siddiqui, RM Anjana, AY Dawed, C Martoeau, S Srinivasan, ... Diabetologia 65 (6), 973-983, 2022 | 46 | 2022 |
Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials AY Dawed, A Mari, A Brown, TJ McDonald, L Li, S Wang, MG Hong, ... The Lancet Diabetes & Endocrinology 11 (1), 33-41, 2023 | 39 | 2023 |
Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI … RW Koivula, IM Forgie, A Kurbasic, A Viñuela, A Heggie, GN Giordano, ... Diabetologia 62, 1601-1615, 2019 | 37 | 2019 |
1851 Identifying Causes for Excess Mortality in Patients With Diabetes: Closer but Not There Yet OHY Yu, S Suissa, SS Rich, WT Cefalu, JS Floyd, BM Psaty, DK Arnett, ... Diabetes Care 39, 1241-1249, 2016 | 36 | 2016 |
Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models RL Allesøe, AT Lundgaard, R Hernández Medina, A Aguayo-Orozco, ... Nature biotechnology 41 (3), 399-408, 2023 | 34 | 2023 |
Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration HR Wilman, CA Parisinos, N Atabaki-Pasdar, M Kelly, EL Thomas, ... Journal of Hepatology 71 (3), 594-602, 2019 | 29 | 2019 |
Genome-wide meta-analysis identifies genetic variants associated with glycemic response to sulfonylureas AY Dawed, SW Yee, K Zhou, N van Leeuwen, Y Zhang, MK Siddiqui, ... Diabetes Care 44 (12), 2673-2682, 2021 | 28 | 2021 |
A polygenic score for type 2 diabetes risk is associated with both the acute and sustained response to sulfonylureas JH Li, L Szczerbinski, AY Dawed, V Kaur, JN Todd, ER Pearson, ... Diabetes 70 (1), 293-300, 2021 | 27 | 2021 |
Common Statin Intolerance Variants in ABCB1 and LILRB5 Show Synergistic Effects on Statin Response: An Observational Study Using Electronic Health Records AL Melhem, MK Chourasia, M Bigossi, C Maroteau, A Taylor, R Pola, ... Frontiers in Genetics 12, 713181, 2021 | 14 | 2021 |
The impact of phenotype, ethnicity and genotype on progression of type 2 diabetes mellitus A Thakarakkattil Narayanan Nair, LA Donnelly, AY Dawed, S Gan, ... Endocrinology, Diabetes & Metabolism 3 (2), e00108, 2020 | 13 | 2020 |
Weight variability and cardiovascular outcomes: a systematic review and meta-analysis RJ Massey, MK Siddiqui, ER Pearson, AY Dawed Cardiovascular Diabetology 22 (1), 5, 2023 | 12 | 2023 |