Asymmetric Preparation of prim-, sec-, and tert-Amines Employing Selected Biocatalysts W Kroutil, EM Fischereder, CS Fuchs, H Lechner, FG Mutti, D Pressnitz, ... Organic process research & development 17 (5), 751-759, 2013 | 139 | 2013 |
Novel carbon–carbon bond formations for biocatalysis V Resch, JH Schrittwieser, E Siirola, W Kroutil Current opinion in biotechnology 22 (6), 793-799, 2011 | 111 | 2011 |
Understanding and Overcoming the Limitations of Bacillus badius and Caldalkalibacillus thermarum Amine Dehydrogenases for Biocatalytic Reductive Amination A Pushpanath, E Siirola, A Bornadel, D Woodlock, U Schell ACS Catalysis 7 (5), 3204-3209, 2017 | 79 | 2017 |
Machine-Directed Evolution of an Imine Reductase for Activity and Stereoselectivity EJ Ma, E Siirola, C Moore, A Kummer, M Stoeckli, M Faller, C Bouquet, ... ACS Catalysis 11 (20), 12433-12445, 2021 | 61 | 2021 |
Asymmetric Synthesis of 3‐Substituted Cyclohexylamine Derivatives from Prochiral Diketones via Three Biocatalytic Steps E Siirola, FG Mutti, B Grischek, SF Hoefler, WMF Fabian, G Grogan, ... Advanced Synthesis & Catalysis 355 (9), 1703-1708, 2013 | 48 | 2013 |
Intensified biocatalytic production of enantiomerically pure halophenylalanines from acrylic acids using ammonium carbamate as the ammonia source NJ Weise, ST Ahmed, F Parmeggiani, E Siirola, A Pushpanath, U Schell, ... Catalysis Science & Technology 6 (12), 4086-4089, 2016 | 33 | 2016 |
C C Hydrolases for Biocatalysis E Siirola, A Frank, G Grogan, W Kroutil Advanced Synthesis & Catalysis 355 (9), 1677-1691, 2013 | 32 | 2013 |
Synthesis of new thiophene, furan and pyridine substituted 1, 2, 4, 5-oxadiazaboroles Y Dürüst, M Akcan, O Martiskainen, E Siirola, K Pihlaja Polyhedron 27 (3), 999-1007, 2008 | 24 | 2008 |
Exploring productive sequence space in directed evolution using binary patterning versus conventional mutagenesis strategies Z Sun, PT Salas, E Siirola, R Lonsdale, MT Reetz Bioresources and Bioprocessing 3 (1), 1-8, 2016 | 23 | 2016 |
Enzymatic Bioconjugation: A Perspective from the Pharmaceutical Industry A Debon, E Siirola, R Snajdrova JACS Au 3 (5), 1267-1283, 2023 | 14 | 2023 |
Tolerance of β‐diketone hydrolases as representatives of the crotonase superfamily towards organic solvents E Siirola, B Grischek, D Clay, A Frank, G Grogan, W Kroutil Biotechnology and bioengineering 108 (12), 2815-2822, 2011 | 13 | 2011 |
Regio‐ and Stereoselective Lipase‐Catalysed Acylation of Methyl α‐D‐Glycopyranosides with Fluorinated β‐Lactams R Sundell, E Siirola, LT Kanerva European Journal of Organic Chemistry 2014 (30), 6753-6760, 2014 | 9 | 2014 |
Mutational Analysis of the C–C Bond Cleaving Enzyme Phloretin Hydrolase from Eubacterium ramulus A Frank, E Siirola, W Kroutil, G Grogan Topics in Catalysis 57, 376-384, 2014 | 9 | 2014 |
Organic solvent tolerance of retro-Friedel–Crafts Hydrolases E Siirola, W Kroutil Topics in Catalysis 57, 392-400, 2014 | 6 | 2014 |
Evolution of Biocatalysis at Novartis over the last 40 Years E Siirola, F Eggimann, C Moore, K Schroer, A Vargas, T Peschke, ... Chimia 77 (6), 376-383, 2023 | 2 | 2023 |
Biocatalytic Reduction of Activated Cinnamic Acid Derivatives: Asymmetric reduction of C= C double bonds using Johnson Matthey enzymes S Staniland, T Angelini, A Pushpanath, A Bornadel, E Siirola, S Bisagni, ... Johnson Matthey Technology Review 64 (4), 529-536, 2020 | | 2020 |
Cipargamin: Biocatalysis in the Discovery and Development of an Antimalarial Drug T Ruch, E Siirola, R Snajdrova Pharmaceutical Biocatalysis, 559-577, 2019 | | 2019 |
Johnson Matthey: A Technology Provider Perspective to Biocatalysis in the Fine Chemicals Industry E Siirola, A Pushpanath, DM Schofield, P Braiuca Biocatalysis, 168-189, 2017 | | 2017 |
Cascade reactions to access optically pure prim-, sec-and test-amines RC Simon, J Sattler, KC Tauber, E Siirola, J Schrittwieser, V Resch, ... Biocat 2012, 2012 | | 2012 |
Biocatalytic CC bond formation and CC cleavage W Kroutil, J Schrittwieser, V Resch, J Sattler, B Seisser, E Siirola, ... | | 2011 |