| A postgenomic method for predicting essential genes at subsaturation levels of mutagenesis: application to Mycobacterium tuberculosis G Lamichhane, M Zignol, NJ Blades, DE Geiman, A Dougherty, J Grosset, ... Proceedings of the National Academy of Sciences 100 (12), 7213-7218, 2003 | 438 | 2003 |
| Copper resistance is essential for virulence of Mycobacterium tuberculosis F Wolschendorf, D Ackart, TB Shrestha, L Hascall-Dove, S Nolan, ... Proceedings of the National Academy of Sciences 108 (4), 1621-1626, 2011 | 357 | 2011 |
| The Mycobacterium tuberculosis protein LdtMt2 is a nonclassical transpeptidase required for virulence and resistance to amoxicillin R Gupta, M Lavollay, JL Mainardi, M Arthur, WR Bishai, G Lamichhane Nature medicine 16 (4), 466-469, 2010 | 309 | 2010 |
| Dormancy Phenotype Displayed by Extracellular Mycobacterium tuberculosis within Artificial Granulomas in Mice PC Karakousis, T Yoshimatsu, G Lamichhane, SC Woolwine, ... The Journal of experimental medicine 200 (5), 647-657, 2004 | 301 | 2004 |
| Cyclic AMP intoxication of macrophages by a Mycobacterium tuberculosis adenylate cyclase N Agarwal, G Lamichhane, R Gupta, S Nolan, WR Bishai Nature 460 (7251), 98-102, 2009 | 255 | 2009 |
| Role of the dosR-dosS Two-Component Regulatory System in Mycobacterium tuberculosis Virulence in Three Animal Models PJ Converse, PC Karakousis, LG Klinkenberg, AK Kesavan, LH Ly, ... Infection and immunity 77 (3), 1230-1237, 2009 | 189 | 2009 |
| Designer Arrays for Defined Mutant Analysis To Detect Genes Essential for Survival of Mycobacterium tuberculosis in Mouse Lungs G Lamichhane, S Tyagi, WR Bishai Infection and immunity 73 (4), 2533-2540, 2005 | 183 | 2005 |
| Genetic requirements for the survival of tubercle bacilli in primates NK Dutta, S Mehra, PJ Didier, CJ Roy, LA Doyle, X Alvarez, M Ratterree, ... The Journal of infectious diseases 201 (11), 1743-1752, 2010 | 182 | 2010 |
| Mycobacterium tuberculosis Invasion and Traversal across an In Vitro Human Blood-Brain Barrier as a Pathogenic Mechanism for Central Nervous System … SK Jain, M Paul-Satyaseela, G Lamichhane, KS Kim, WR Bishai The Journal of infectious diseases 193 (9), 1287-1295, 2006 | 170 | 2006 |
| Carbapenems and rifampin exhibit synergy against Mycobacterium tuberculosis and Mycobacterium abscessus A Kaushik, N Makkar, P Pandey, N Parrish, U Singh, G Lamichhane Antimicrobial agents and chemotherapy 59 (10), 6561-6567, 2015 | 132 | 2015 |
| Non-classical transpeptidases yield insight into new antibacterials P Kumar, A Kaushik, EP Lloyd, SG Li, R Mattoo, NC Ammerman, DT Bell, ... Nature chemical biology 13 (1), 54-61, 2017 | 129 | 2017 |
| Targeting the Cell Wall of Mycobacterium tuberculosis: Structure and Mechanism of L, D-Transpeptidase 2 S Erdemli, R Gupta, W Bishai, G Lamichhane, L Amzel, M Bianchet Structure 20 (12), 2013-15, 2012 | 125 | 2012 |
| Novel targets in M. tuberculosis: search for new drugs G Lamichhane Trends in molecular medicine 17 (1), 25-33, 2011 | 117 | 2011 |
| Drug resistance mechanisms and novel drug targets for tuberculosis therapy MM Islam, HMA Hameed, J Mugweru, C Chhotaray, C Wang, Y Tan, J Liu, ... Journal of genetics and genomics 44 (1), 21-37, 2017 | 113 | 2017 |
| Nonclassical transpeptidases of Mycobacterium tuberculosis alter cell size, morphology, the cytosolic matrix, protein localization, virulence, and resistance to β-lactams MK Schoonmaker, WR Bishai, G Lamichhane Journal of bacteriology 196 (7), 1394-1402, 2014 | 110 | 2014 |
| Inhibition of innate immune cytosolic surveillance by an M. tuberculosis phosphodiesterase RJ Dey, B Dey, Y Zheng, LS Cheung, J Zhou, D Sayre, P Kumar, H Guo, ... Nature chemical biology 13 (2), 210-217, 2017 | 92 | 2017 |
| Murine Model to Study the Invasion and Survival of Mycobacterium tuberculosis in the Central Nervous System NA Be, G Lamichhane, J Grosset, S Tyagi, QJ Cheng, KS Kim, WR Bishai, ... The Journal of infectious diseases 198 (10), 1520-1528, 2008 | 86 | 2008 |
| Methionine aminopeptidases from Mycobacterium tuberculosis as novel antimycobacterial targets O Olaleye, TR Raghunand, S Bhat, J He, S Tyagi, G Lamichhane, P Gu, ... Chemistry & biology 17 (1), 86-97, 2010 | 78 | 2010 |
| Structural and functional features of enzymes of Mycobacterium tuberculosis peptidoglycan biosynthesis as targets for drug development GL Moraes, GC Gomes, PRM De Sousa, CN Alves, T Govender, ... Tuberculosis 95 (2), 95-111, 2015 | 77 | 2015 |
| Substituted N-Phenyl-5-(2-(phenylamino)thiazol-4-yl)isoxazole-3-carboxamides Are Valuable Antitubercular Candidates that Evade Innate Efflux Machinery E Azzali, D Machado, A Kaushik, F Vacondio, S Flisi, CS Cabassi, ... Journal of medicinal chemistry 60 (16), 7108-7122, 2017 | 76 | 2017 |
