| PharmacoGx: an R package for analysis of large pharmacogenomic datasets P Smirnov, Z Safikhani, N El-Hachem, D Wang, A She, C Olsen, ... Bioinformatics 32 (8), 1244-1246, 2016 | 265 | 2016 |
| Identification of Predictive Markers of Response to the MEK1/2 Inhibitor Selumetinib (AZD6244) in K-ras–Mutated Colorectal Cancer JJ Tentler, S Nallapareddy, AC Tan, A Spreafico, TM Pitts, MP Morelli, ... Molecular cancer therapeutics 9 (12), 3351-3362, 2010 | 92 | 2010 |
| Rational combination of a MEK inhibitor, selumetinib, and the Wnt/calcium pathway modulator, cyclosporin A, in preclinical models of colorectal cancer A Spreafico, JJ Tentler, TM Pitts, AC Tan, MA Gregory, JJ Arcaroli, ... Clinical Cancer Research 19 (15), 4149-4162, 2013 | 76 | 2013 |
| BatchQC: interactive software for evaluating sample and batch effects in genomic data S Manimaran, HM Selby, K Okrah, C Ruberman, JT Leek, J Quackenbush, ... Bioinformatics 32 (24), 3836-3838, 2016 | 65 | 2016 |
| Overcoming IGF1R/IR resistance through inhibition of MEK signaling in colorectal cancer models SA Flanigan, TM Pitts, TP Newton, GN Kulikowski, AC Tan, MC McManus, ... Clinical cancer research 19 (22), 6219-6229, 2013 | 62 | 2013 |
| A meta-learning approach for genomic survival analysis YL Qiu, H Zheng, A Devos, H Selby, O Gevaert Nature communications 11 (1), 6350, 2020 | 56 | 2020 |
| Predictive biomarkers of sensitivity to the aurora and angiogenic kinase inhibitor ENMD-2076 in preclinical breast cancer models JR Diamond, SG Eckhardt, AC Tan, TP Newton, HM Selby, KL Brunkow, ... Clinical Cancer Research 19 (1), 291-303, 2013 | 53 | 2013 |
| Association of the epithelial-to-mesenchymal transition phenotype with responsiveness to the p21-activated kinase inhibitor, PF-3758309, in colon cancer models TM Pitts, GN Kulikowski, AC Tan, BW Murray, JJ Arcaroli, JJ Tentler, ... Frontiers in pharmacology 4, 35, 2013 | 44 | 2013 |
| A survey of statistical software for analysing RNA-seq data D Gao, J Kim, H Kim, TL Phang, H Selby, AC Tan, T Tong Human genomics 5, 1-5, 2010 | 40 | 2010 |
| A short survey of computational analysis methods in analysing ChIP-seq data H Kim, J Kim, H Selby, D Gao, T Tong, T Lip Phang, A Choon Tan Human genomics 5, 1-7, 2011 | 37 | 2011 |
| Antitumor activity of the MEK inhibitor TAK-733 against melanoma cell lines and patient-derived tumor explants LN Micel, JJ Tentler, AC Tan, HM Selby, KL Brunkow, KM Robertson, ... Molecular cancer therapeutics 14 (2), 317-325, 2015 | 31 | 2015 |
| Utilization of quantitative in vivo pharmacology approaches to assess combination effects of everolimus and irinotecan in mouse xenograft models of colorectal cancer EL Bradshaw-Pierce, TM Pitts, G Kulikowski, H Selby, AL Merz, ... PloS one 8 (3), e58089, 2013 | 31 | 2013 |
| Antitumor activity of the aurora a selective kinase inhibitor, alisertib, against preclinical models of colorectal cancer TM Pitts, EL Bradshaw, SM Bagby, SL Hyatt, HM Selby, A Spreafico, ... Oncotarget 7 (31), 50290, 2016 | 28 | 2016 |
| Targeting the protein ubiquitination machinery in melanoma by the NEDD8-activating enzyme inhibitor pevonedistat (MLN4924) KM Wong, LN Micel, HM Selby, AC Tan, TM Pitts, SM Bagby, A Spreafico, ... Investigational new drugs 35, 11-25, 2017 | 25 | 2017 |
| Combined inhibition of MEK and Aurora A kinase in KRAS/PIK3CA double-mutant colorectal cancer models SL Davis, KM Robertson, TM Pitts, JJ Tentler, EL Bradshaw-Pierce, ... Frontiers in pharmacology 6, 120, 2015 | 24 | 2015 |
| Rational design and identification of immuno-oncology drug combinations MAJ Iafolla, H Selby, K Warner, PS Ohashi, B Haibe-Kains, LL Siu European Journal of Cancer 95, 38-51, 2018 | 15 | 2018 |
| Antitumor activity of the polo-like kinase inhibitor, TAK-960, against preclinical models of colorectal cancer PJ Klauck, SM Bagby, A Capasso, EL Bradshaw-Pierce, HM Selby, ... BMC cancer 18, 1-12, 2018 | 14 | 2018 |
| Antitumor activity of a potent MEK inhibitor, TAK-733, against colorectal cancer cell lines and patient derived xenografts CH Lieu, PJ Klauck, PK Henthorn, JJ Tentler, AC Tan, A Spreafico, ... Oncotarget 6 (33), 34561, 2015 | 13 | 2015 |
| Topological data analysis of thoracic radiographic images shows improved radiomics-based lung tumor histology prediction R Vandaele, P Mukherjee, HM Selby, RP Shah, O Gevaert Patterns 4 (1), 2023 | 8 | 2023 |
| Machine learning radiomics model for early identification of small-cell lung cancer on computed tomography scans RP Shah, HM Selby, P Mukherjee, S Verma, P Xie, Q Xu, M Das, S Malik, ... JCO Clinical Cancer Informatics 5, 746-757, 2021 | 6 | 2021 |
