Donor variation and loss of multipotency during in vitro expansion of human mesenchymal stem cells for bone tissue engineering R Siddappa, R Licht, C Van Blitterswijk, J De Boer Journal of orthopaedic research 25 (8), 1029-1041, 2007 | 379 | 2007 |
Wnt signaling inhibits osteogenic differentiation of human mesenchymal stem cells J de Boer, R Siddappa, C Gaspar, A van Apeldoorn, R Fodde, ... Bone 34 (5), 818-826, 2004 | 302 | 2004 |
cAMP/PKA pathway activation in human mesenchymal stem cells in vitro results in robust bone formation in vivo R Siddappa, A Martens, J Doorn, A Leusink, C Olivo, R Licht, L Van Rijn, ... Proceedings of the National Academy of Sciences 105 (20), 7281-7286, 2008 | 261 | 2008 |
The response of human mesenchymal stem cells to osteogenic signals and its impact on bone tissue engineering R Siddappa, H Fernandes, J Liu, C Blitterswijk, J de Boer Current stem cell research & therapy 2 (3), 209-220, 2007 | 91 | 2007 |
cAMP/PKA signaling inhibits osteogenic differentiation and bone formation in rodent models R Siddappa, W Mulder, I Steeghs, C van de Klundert, H Fernandes, J Liu, ... Tissue Engineering Part A 15 (8), 2135-2143, 2009 | 70 | 2009 |
Systems biology approach identifies the kinase Csnk1a1 as a regulator of the DNA damage response in embryonic stem cells J Carreras Puigvert, L von Stechow, R Siddappa, A Pines, M Bahjat, ... Science signaling 6 (259), ra5-ra5, 2013 | 51 | 2013 |
The E3 ubiquitin ligase ARIH1 protects against genotoxic stress by initiating a 4EHP-mediated mRNA translation arrest L von Stechow, D Typas, JC Puigvert, L Oort, R Siddappa, A Pines, ... Molecular and cellular biology, 2015 | 48 | 2015 |
Forskolin Enhances In Vivo Bone Formation by Human Mesenchymal Stromal Cells J Doorn, R Siddappa, CA van Blitterswijk, J de Boer Tissue Engineering Part A 18 (5-6), 558-567, 2012 | 38 | 2012 |
Timing, rather than the concentration of cyclic AMP, correlates to osteogenic differentiation of human mesenchymal stem cells R Siddappa, J Doorn, J Liu, E Langerwerf, R Arends, C van Blitterswijk, ... Journal of tissue engineering and regenerative medicine 4 (5), 356-365, 2010 | 34 | 2010 |
Tissue Engineering-an introduction C van Blitterswijk, L Moroni, J Rouwkema, R Siddappa, J Sohier Tissue Engineering, 13-36, 2008 | 17 | 2008 |
Cellular and molecular prerequisites for bone tissue engineering R Siddappa | 3 | 2007 |
Supercritical CO2: the future for cleaner and safer tissues for regenerative medicine D Link, R Siddappa, M Thio, B Babychan, H Valster JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE 8, 135-135, 2014 | 1 | 2014 |
Protein Kinase A exhibits both paracrine and cell-autonomous control of bone formation by human mesenchymal stem cells R Siddappaa, C van Blitterswijka, C Gasparb, R Foddeb, C Olivoc, ... Cellular and Molecular Prerequisites for Bone Tissue Engineering, 91, 2007 | 1 | 2007 |
State of the Heart Technology: Decellularised Pericardium by Supercritical Carbon Dioxide Processing for Cardiothoracic Surgery Applications FR Halfwerk, F Damanik, J Rouwkema, L Moroni, R Siddappa, ... Wetenschapsdag Medisch Spectrum Twente 2014, 2014 | | 2014 |
State of the Heart Technology: The Potential of Decellularised Pericardium by Supercritical Carbon Dioxide Processing for Cardiothoracic Surgery FR Halfwerk, F Damanik, J Rouwkema, L Moroni, R Siddappa, ... Netherlands heart journal 22 (Supplement), S13, 2014 | | 2014 |
A role for Protein Kinase A in osteogenic cell fate decision of human mesenchymal stem cells J Doorn, R Siddappa, J Liu, E Langerwerf, R Arends, C van Blitterswijk, ... ISSCR annual meeting, 2009 | | 2009 |
Timing rather than the concentration of cAMP correlates to osteogenic differentiation of hMSCs J Doorn, R Siddappa, J Liu, E Langerwerf, R Arends, C van Blitterswijk, ... Stem cells of Biology, 2008 | | 2008 |
Activation of the cAMP/PKA pathway in human mesenchymal stem cells in vitro results in robust bone formation in vivo R Siddappa, J Doorn, A Leusink, C van Blitterswijk, J de Boer Bone, S30, 2008 | | 2008 |
Optimizing protein kinase A activation to enhance osteogenic differentiation of human mesenchymal stem cells. J Doorn, R Siddappa, C van Blitterswijk, J de Boer | | 2007 |
Controlling osteogenesis by/of human mesenchymal cells R Siddappa, R Licht, J Liu, C van Blitterswijk, J de Boer European cells & materials 14 (Suppl. 1), 36, 2007 | | 2007 |