Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism P Hasel, O Dando, Z Jiwaji, P Baxter, AC Todd, S Heron, NM Márkus, ... Nature communications 8 (1), 15132, 2017 | 286 | 2017 |
Adaptive regulation of the brain’s antioxidant defences by neurons and astrocytes PS Baxter, GE Hardingham Free Radical Biology and Medicine 100, 147-152, 2016 | 232 | 2016 |
Specific targeting of pro-death NMDA receptor signals with differing reliance on the NR2B PDZ ligand FX Soriano, MA Martel, S Papadia, A Vaslin, P Baxter, C Rickman, ... Journal of Neuroscience 28 (42), 10696-10710, 2008 | 185 | 2008 |
Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2 KFS Bell, B Al-Mubarak, MA Martel, S McKay, N Wheelan, P Hasel, ... Nature communications 6 (1), 7066, 2015 | 183 | 2015 |
Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning KF Bell, B Al-Mubarak, JH Fowler, PS Baxter, K Gupta, T Tsujita, ... Proceedings of the National Academy of Sciences 108 (1), E1-E2, 2011 | 158 | 2011 |
Transcriptional regulation of the AP-1 and Nrf2 target gene sulfiredoxin FX Soriano, P Baxter, LM Murray, MB Sporn, TH Gillingwater, ... Molecules and cells 27, 279-282, 2009 | 148 | 2009 |
Synaptic NMDA receptor activity is coupled to the transcriptional control of the glutathione system PS Baxter, KFS Bell, P Hasel, AM Kaindl, M Fricker, D Thomson, ... Nature communications 6 (1), 6761, 2015 | 147 | 2015 |
Induction of sulfiredoxin expression and reduction of peroxiredoxin hyperoxidation by the neuroprotective Nrf2 activator 3H‐1, 2‐dithiole‐3‐thione FX Soriano, F Léveillé, S Papadia, LG Higgins, J Varley, P Baxter, ... Journal of neurochemistry 107 (2), 533-543, 2008 | 147 | 2008 |
Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology Z Jiwaji, SS Tiwari, RX Avilés-Reyes, M Hooley, D Hampton, M Torvell, ... Nature communications 13 (1), 135, 2022 | 129 | 2022 |
SK channel modulation rescues striatal plasticity and control over habit in cannabinoid tolerance C Nazzaro, B Greco, M Cerovic, P Baxter, T Rubino, M Trusel, D Parolaro, ... Nature neuroscience 15 (2), 284-293, 2012 | 112 | 2012 |
Human embryonic stem cell derived astrocytes mediate non-cell-autonomous neuroprotection through endogenous and drug-induced mechanisms K Gupta, R Patani, P Baxter, A Serio, D Story, T Tsujita, JD Hayes, ... Cell Death & Differentiation 19 (5), 779-787, 2012 | 103 | 2012 |
Microglial identity and inflammatory responses are controlled by the combined effects of neurons and astrocytes PS Baxter, O Dando, K Emelianova, X He, S McKay, GE Hardingham, ... Cell reports 34 (12), 2021 | 83 | 2021 |
Phosphoinositide 3-Kinases Upregulate System xc− via Eukaryotic Initiation Factor 2α and Activating Transcription Factor 4 – A Pathway Active in … J Lewerenz, P Baxter, R Kassubek, P Albrecht, J Van Liefferinge, ... Antioxidants & redox signaling 20 (18), 2907-2922, 2014 | 75 | 2014 |
Mitochondrial dysfunction induced by nuclear poly (ADP-ribose) polymerase-1: a treatable cause of cell death in stroke P Baxter, Y Chen, Y Xu, RA Swanson Translational stroke research 5, 136-144, 2014 | 71 | 2014 |
Pituitary adenylate cyclase‐activating peptide induces long‐lasting neuroprotection through the induction of activity‐dependent signaling via the cyclic AMP response element … PS Baxter, MA Martel, A McMahon, PC Kind, GE Hardingham Journal of neurochemistry 118 (3), 365-378, 2011 | 56 | 2011 |
Pro-death NMDA receptor signaling is promoted by the GluN2B C-terminus independently of Dapk1 J McQueen, TJ Ryan, S McKay, K Marwick, P Baxter, SM Carpanini, ... Elife 6, e17161, 2017 | 54 | 2017 |
The developmental shift of NMDA receptor composition proceeds independently of GluN2 subunit-specific GluN2 C-terminal sequences S McKay, TJ Ryan, J McQueen, T Indersmitten, KFM Marwick, P Hasel, ... Cell reports 25 (4), 841-851. e4, 2018 | 46 | 2018 |
Input-output relationship of CA1 pyramidal neurons reveals intact homeostatic mechanisms in a mouse model of fragile X syndrome SA Booker, LS De Oliveira, NJ Anstey, Z Kozic, OR Dando, AD Jackson, ... Cell Reports 32 (6), 2020 | 44 | 2020 |
Inhibiting pro-death NMDA receptor signaling dependent on the NR2 PDZ ligand may not affect synaptic function or synaptic NMDA receptor signaling to gene expression MA Martel, FX Soriano, P Baxter, C Rickman, R Duncan, DJA Wyllie, ... Channels 3 (1), 12-15, 2009 | 43 | 2009 |
Mixed-species RNA-seq for elucidation of non-cell-autonomous control of gene transcription J Qiu, O Dando, PS Baxter, P Hasel, S Heron, TI Simpson, ... Nature Protocols 13 (10), 2176-2199, 2018 | 36 | 2018 |