The impact of chromatin dynamics on Cas9-mediated genome editing in human cells RM Daer, JP Cutts, DA Brafman, KA Haynes ACS synthetic biology 6 (3), 428-438, 2017 | 167 | 2017 |
Preparing synthetic biology for the world GHG Moe-Behrens, R Davis, KA Haynes Frontiers in microbiology 4, 5, 2013 | 158 | 2013 |
Fund black scientists KR Stevens, KS Masters, PI Imoukhuede, KA Haynes, LA Setton, ... Cell 184 (3), 561-565, 2021 | 132 | 2021 |
cis-Acting determinants of heterochromatin formation on Drosophila melanogaster chromosome four FL Sun, K Haynes, CL Simpson, SD Lee, L Collins, J Wuller, ... Molecular and cellular biology, 2004 | 131 | 2004 |
Element 1360 and RNAi components contribute to HP1-dependent silencing of a pericentric reporter KA Haynes, AA Caudy, L Collins, SCR Elgin Current Biology 16 (22), 2222-2227, 2006 | 98 | 2006 |
The living interface between synthetic biology and biomaterial design AP Liu, EA Appel, PD Ashby, BM Baker, E Franco, L Gu, K Haynes, ... Nature materials 21 (4), 390-397, 2022 | 93 | 2022 |
Engineering bacteria to solve the Burnt Pancake Problem KA Haynes, ML Broderick, AD Brown, TL Butner, JO Dickson, WL Harden, ... Journal of biological engineering 2, 1-12, 2008 | 81 | 2008 |
Can the natural diversity of quorum-sensing advance synthetic biology? RM Davis, RY Muller, KA Haynes Frontiers in bioengineering and biotechnology 3, 30, 2015 | 78 | 2015 |
Synthetic reversal of epigenetic silencing KA Haynes, PA Silver Journal of Biological Chemistry 286 (31), 27176-27182, 2011 | 72 | 2011 |
The sound of silence: Transgene silencing in mammalian cell engineering A Cabrera, HI Edelstein, F Glykofrydis, KS Love, S Palacios, J Tycko, ... Cell Systems 13 (12), 950-973, 2022 | 53 | 2022 |
Eukaryotic systems broaden the scope of synthetic biology KA Haynes, PA Silver Journal of Cell Biology 187 (5), 589-596, 2009 | 53 | 2009 |
A Distinct Type of Heterochromatin Within Drosophila melanogaster Chromosome 4 KA Haynes, E Gracheva, SCR Elgin Genetics 175 (3), 1539-1542, 2007 | 40 | 2007 |
An Investigation of Heterochromatin Domains on the Fourth Chromosome of Drosophila melanogaster NC Riddle, W Leung, KA Haynes, H Granok, J Wuller, SCR Elgin Genetics 178 (3), 1177-1191, 2008 | 37 | 2008 |
A BioBrick compatible strategy for genetic modification of plants PM Boyle, DR Burrill, MC Inniss, CM Agapakis, A Deardon, JG DeWerd, ... Journal of biological engineering 6, 1-8, 2012 | 33 | 2012 |
Engineered Orthogonal Quorum Sensing Systems for Synthetic Gene Regulation in Escherichia coli SJ Tekel, CL Smith, B Lopez, A Mani, C Connot, X Livingstone, ... Frontiers in Bioengineering and Biotechnology 7, 80, 2019 | 27 | 2019 |
Molecular structures guide the engineering of chromatin SJ Tekel, KA Haynes Nucleic acids research 45 (13), 7555-7570, 2017 | 24 | 2017 |
Tandem histone-binding domains enhance the activity of a synthetic chromatin effector SJ Tekel, DA Vargas, L Song, J LaBaer, MR Caplan, KA Haynes ACS synthetic biology 7 (3), 842-852, 2018 | 21 | 2018 |
The histone deacetylase inhibitor Entinostat enhances polymer‐mediated transgene expression in cancer cell lines JJ Elmer, MD Christensen, S Barua, J Lehrman, KA Haynes, K Rege Biotechnology and bioengineering 113 (6), 1345-1356, 2016 | 19 | 2016 |
Beyond the marks: reader-effectors as drivers of epigenetics and chromatin engineering KA Franklin, CE Shields, KA Haynes Trends in biochemical sciences 47 (5), 417-432, 2022 | 18 | 2022 |
Regulation of cancer epigenomes with a histone-binding synthetic transcription factor DB Nyer, RM Daer, D Vargas, C Hom, KA Haynes NPJ genomic medicine 2 (1), 1, 2017 | 18 | 2017 |