Activation of the renal Na+: Cl− cotransporter by angiotensin II is a WNK4-dependent process M Castañeda-Bueno, LG Cervantes-Pérez, N Vázquez, N Uribe, ... Proceedings of the National Academy of Sciences 109 (20), 7929-7934, 2012 | 276 | 2012 |
WNK3 modulates transport of Cl-in and out of cells: implications for control of cell volume and neuronal excitability KT Kahle, J Rinehart, P de Los Heros, A Louvi, P Meade, N Vazquez, ... Proceedings of the National Academy of Sciences 102 (46), 16783-16788, 2005 | 266 | 2005 |
Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathway P San-Cristobal, D Pacheco-Alvarez, C Richardson, AM Ring, N Vazquez, ... Proceedings of the National Academy of Sciences 106 (11), 4384-4389, 2009 | 259 | 2009 |
The Na+: Cl–cotransporter is activated and phosphorylated at the amino-terminal domain upon intracellular chloride depletion D Pacheco-Alvarez, P San Cristóbal, P Meade, E Moreno, N Vazquez, ... Journal of Biological Chemistry 281 (39), 28755-28763, 2006 | 256 | 2006 |
Identification and functional characterization of cation–chloride cotransporters in plants JM Colmenero‐Flores, G Martínez, G Gamba, N Vázquez, DJ Iglesias, ... The Plant Journal 50 (2), 278-292, 2007 | 255 | 2007 |
Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases J Ponce-Coria, P San-Cristobal, KT Kahle, N Vazquez, ... Proceedings of the National Academy of Sciences 105 (24), 8458-8463, 2008 | 236 | 2008 |
WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl-cotransporters required for normal blood pressure homeostasis J Rinehart, KT Kahle, P de Los Heros, N Vazquez, P Meade, FH Wilson, ... Proceedings of the National Academy of Sciences 102 (46), 16777-16782, 2005 | 218 | 2005 |
Functional comparison of the K+-Cl− cotransporters KCC1 and KCC4 A Mercado, L Song, N Vázquez, DB Mount, G Gamba Journal of Biological Chemistry 275 (39), 30326-30334, 2000 | 207 | 2000 |
Nedd4-2 modulates renal Na+-Cl− cotransporter via the aldosterone-SGK1-Nedd4-2 pathway JP Arroyo, D Lagnaz, C Ronzaud, N Vázquez, BS Ko, L Moddes, ... Journal of the American Society of Nephrology 22 (9), 1707-1719, 2011 | 186 | 2011 |
The effect of WNK4 on the Na+–Cl− cotransporter is modulated by intracellular chloride S Bazúa-Valenti, M Chávez-Canales, L Rojas-Vega, ... Journal of the American Society of Nephrology 26 (8), 1781-1786, 2015 | 162 | 2015 |
WNK3 bypasses the tonicity requirement for K-Cl cotransporter activation via a phosphatase-dependent pathway P de Los Heros, KT Kahle, J Rinehart, NA Bobadilla, N Vázquez, ... Proceedings of the National Academy of Sciences 103 (6), 1976-1981, 2006 | 154 | 2006 |
Molecular, functional, and genomic characterization of human KCC2, the neuronal K–Cl cotransporter L Song, A Mercado, N Vázquez, Q Xie, R Desai, AL George Jr, G Gamba, ... Molecular Brain Research 103 (1-2), 91-105, 2002 | 131 | 2002 |
N-Glycosylation at Two Sites Critically Alters Thiazide Binding and Activity of the Rat Thiazide-sensitive Na+: Cl:−: Cotransporter RS Hoover, E Poch, A Monroy, N Vázquez, T Nishio, G Gamba, ... Journal of the American Society of Nephrology 14 (2), 271-282, 2003 | 122 | 2003 |
Functional properties of the apical Na+-K+-2Cl− cotransporter isoforms C Plata, P Meade, N Vázquez, SC Hebert, G Gamba Journal of Biological Chemistry 277 (13), 11004-11012, 2002 | 122 | 2002 |
Modulation of NCC activity by low and high K+ intake: insights into the signaling pathways involved M Castañeda-Bueno, LG Cervantes-Perez, L Rojas-Vega, I Arroyo-Garza, ... American Journal of Physiology-Renal Physiology 306 (12), F1507-F1519, 2014 | 114 | 2014 |
Pathophysiology of functional mutations of the thiazide-sensitive Na-Cl cotransporter in Gitelman disease E Sabath, P Meade, J Berkman, P De Los Heros, E Moreno, NA Bobadilla, ... American Journal of Physiology-Renal Physiology 287 (2), F195-F203, 2004 | 108 | 2004 |
NH2-terminal heterogeneity in the KCC3 K+-Cl− cotransporter A Mercado, N Vázquez, L Song, R Cortés, AH Enck, R Welch, E Delpire, ... American Journal of Physiology-Renal Physiology 289 (6), F1246-F1261, 2005 | 103 | 2005 |
WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters J Rinehart, N Vázquez, KT Kahle, CA Hodson, AM Ring, EE Gulcicek, ... Journal of Biological Chemistry 286 (34), 30171-30180, 2011 | 101 | 2011 |
WNK4 kinase is a negative regulator of K+-Cl− cotransporters T Garzón-Muvdi, D Pacheco-Alvarez, KBE Gagnon, N Vázquez, ... American Journal of Physiology-Renal Physiology 292 (4), F1197-F1207, 2007 | 96 | 2007 |
WNK-SPAK-NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4 M Chávez-Canales, C Zhang, C Soukaseum, E Moreno, ... Hypertension 64 (5), 1047-1053, 2014 | 95 | 2014 |