Ataluren (PTC124) induces cystic fibrosis transmembrane conductance regulator protein expression and activity in children with nonsense mutation cystic fibrosis I Sermet-Gaudelus, K De Boeck, GJ Casimir, F Vermeulen, T Leal, ... American journal of respiratory and critical care medicine 182 (10), 1262-1272, 2010 | 289 | 2010 |
Cystic fibrosis: insight into CFTR pathophysiology and pharmacotherapy B Lubamba, B Dhooghe, S Noel, T Leal Clinical Biochemistry, 2012 | 214 | 2012 |
Azithromycin reduces exaggerated cytokine production by M1 alveolar macrophages in cystic fibrosis. M Meyer, F Huaux, X Gavilanes, S van den Brule, P Lebecque, RS Lo, ... American journal of respiratory cell and molecular biology 41 (5), 590, 2009 | 159 | 2009 |
Azithromycin reduces spontaneous and induced inflammation in ΔF508 cystic fibrosis mice R Legssyer, F Huaux, J Lebacq, M Delos, E Marbaix, P Lebecque, ... Respiratory research 7, 1-13, 2006 | 130 | 2006 |
CFTR biomarkers: time for promotion to surrogate end-point K De Boeck, L Kent, J Davies, N Derichs, M Amaral, SM Rowe, ... European Respiratory Journal 41 (1), 203-216, 2013 | 121 | 2013 |
Cystic fibrosis is associated with a defect in apical receptor–mediated endocytosis in mouse and human kidney A Bernard, C Hermans, G Dom, S Terryn, T Leal, P Lebecque, ... Journal of the American Society of Nephrology 18 (3), 707-718, 2007 | 120 | 2007 |
SUMOylation of tissue transglutaminase as link between oxidative stress and inflammation A Luciani, VR Villella, A Vasaturo, I Giardino, V Raia, ... The Journal of Immunology 183 (4), 2775-2784, 2009 | 111 | 2009 |
The role of epithelial P2Y2 and P2Y4 receptors in the regulation of intestinal chloride secretion E Ghanem, B Robaye, T Leal, J Leipziger, WV Driessche, R Beauwens, ... British journal of pharmacology 146 (3), 364-369, 2009 | 94 | 2009 |
Basic protocol for transepithelial nasal potential difference measurements D Schüler, I Sermet-Gaudelus, M Wilschanski, M Ballmann, M Dechaux, ... Journal of Cystic Fibrosis 3, 151-155, 2004 | 92 | 2004 |
Vancomycin penetration of uninfected pleural fluid exudate after continuous or intermittent infusion B Byl, F Jacobs, P Wallemacq, C Rossi, P De Francquen, M Cappello, ... Antimicrobial agents and chemotherapy 47 (6), 2015-2017, 2003 | 88 | 2003 |
Preclinical Evidence that Sildenafil and Vardenafil Activate Chloride Transport in Cystic Fibrosis T Leal American journal of respiratory and critical care medicine: an official …, 2008 | 85* | 2008 |
Congenital tracheal malformation in cystic fibrosis transmembrane conductance regulator‐deficient mice E Bonvin, P Le Rouzic, JF Bernaudin, CH Cottart, C Vandebrouck, A Crié, ... The Journal of physiology 586 (13), 3231-3243, 2008 | 83 | 2008 |
Mutations of the cystic fibrosis gene and intermediate sweat chloride levels in children P Lebecque, T Leal, C De Boeck, M Jaspers, H Cuppens, JJ Cassiman American journal of respiratory and critical care medicine 165 (6), 757-761, 2002 | 83 | 2002 |
Cystic fibrosis transmembrane conductance regulator modulators in cystic fibrosis: current perspectives BZ Schmidt, JB Haaf, T Leal, S Noel Clinical pharmacology: advances and applications, 127-140, 2016 | 81 | 2016 |
Mutations of cystic fibrosis transmembrane conductance regulator gene cause a monocyte-selective adhesion deficiency C Sorio, A Montresor, M Bolomini-Vittori, S Caldrer, B Rossi, S Dusi, ... American journal of respiratory and critical care medicine 193 (10), 1123-1133, 2016 | 79 | 2016 |
Delivery efficacy of a vibrating mesh nebulizer and a jet nebulizer under different configurations L Pitance, L Vecellio, T Leal, G Reychler, H Reychler, G Liistro Journal of aerosol medicine and pulmonary drug delivery 23 (6), 389-396, 2010 | 76 | 2010 |
An overview of monitoring and supplementation of omega 3 fatty acids in cystic fibrosis TC Coste, M Armand, J Lebacq, P Lebecque, P Wallemacq, T Leal Clinical biochemistry 40 (8), 511-520, 2007 | 76 | 2007 |
Lung inflammation in cystic fibrosis: pathogenesis and novel therapies B Dhooghe, S Noël, F Huaux, T Leal Clinical biochemistry 47 (7-8), 539-546, 2014 | 73 | 2014 |
Early referral to cystic fibrosis specialist centre impacts on respiratory outcome P Lebecque, A Leonard, K De Boeck, F De Baets, A Malfroot, G Casimir, ... Journal of Cystic Fibrosis 8 (1), 26-30, 2009 | 73 | 2009 |
Airway delivery of low-dose miglustat normalizes nasal potential difference in F508del cystic fibrosis mice B Lubamba, J Lebacq, P Lebecque, R Vanbever, A Leonard, ... American journal of respiratory and critical care medicine 179 (11), 1022-1028, 2009 | 60 | 2009 |