Anticancer effects of imperatorin isolated from Angelica dahurica: induction of apoptosis in HepG2 cells through both death-receptor-and mitochondria-mediated pathways K Luo, J Sun, JYW Chan, L Yang, S Wu, KP Fung, F Liu Chemotherapy 57 (6), 449-459, 2012 | 159 | 2012 |
Andrographolide enhances 5-fluorouracil-induced apoptosis via caspase-8-dependent mitochondrial pathway involving p53 participation in hepatocellular carcinoma (SMMC-7721) cells L Yang, D Wu, K Luo, S Wu, P Wu Cancer letters 276 (2), 180-188, 2009 | 142 | 2009 |
Anti-proliferative effect of clitocine from the mushroom Leucopaxillus giganteus on human cervical cancer HeLa cells by inducing apoptosis G Ren, Y Zhao, L Yang, CX Fu Cancer Letters 262 (2), 190-200, 2008 | 109 | 2008 |
23, 24-Dihydrocucurbitacin B induces G2/M cell-cycle arrest and mitochondria-dependent apoptosis in human breast cancer cells (Bcap37) L Yang, S Wu, Q Zhang, F Liu, P Wu Cancer letters 256 (2), 267-278, 2007 | 103 | 2007 |
Allyl isothiocyanate arrests cancer cells in mitosis, and mitotic arrest in turn leads to apoptosis via Bcl-2 protein phosphorylation F Geng, L Tang, Y Li, L Yang, KS Choi, AL Kazim, Y Zhang Journal of Biological Chemistry 286 (37), 32259-32267, 2011 | 94 | 2011 |
Ursolic acid induces doxorubicin-resistant HepG2 cell death via the release of apoptosis-inducing factor L Yang, X Liu, Z Lu, JYW Chan, LL Zhou, KP Fung, P Wu, S Wu Cancer Letters 298 (1), 128-138, 2010 | 90 | 2010 |
Multi-channel counter-current chromatography for high-throughput fractionation of natural products for drug discovery S Wu, L Yang, Y Gao, X Liu, F Liu Journal of chromatography A 1180 (1-2), 99-107, 2008 | 74 | 2008 |
Idiopathic autism: cellular and molecular phenotypes in pluripotent stem cell-derived neurons X Liu, E Campanac, HH Cheung, MN Ziats, L Canterel-Thouennon, ... Molecular neurobiology 54, 4507-4523, 2017 | 73 | 2017 |
pH-gradient counter-current chromatography isolation of natural antioxidant chlorogenic acid from Lonicera japonica Thumb. using an upright coil planet centrifuge with three … T Wang, X Jiang, L Yang, S Wu Journal of Chromatography A 1180 (1-2), 53-58, 2008 | 63 | 2008 |
Prolidase directly binds and activates epidermal growth factor receptor and stimulates downstream signaling L Yang, Y Li, Y Ding, KS Choi, AL Kazim, Y Zhang Journal of Biological Chemistry 288 (4), 2365-2375, 2013 | 38 | 2013 |
Identification of prolidase as a high affinity ligand of the ErbB2 receptor and its regulation of ErbB2 signaling and cell growth L Yang, Y Li, Y Zhang Cell death & disease 5 (5), e1211-e1211, 2014 | 33 | 2014 |
A recombinant human protein targeting HER2 overcomes drug resistance in HER2-positive breast cancer L Yang, Y Li, A Bhattacharya, Y Zhang Science translational medicine 11 (476), eaav1620, 2019 | 31 | 2019 |
PEPD is a pivotal regulator of p53 tumor suppressor L Yang, Y Li, A Bhattacharya, Y Zhang Nature communications 8 (1), 2052, 2017 | 28 | 2017 |
A plasma proteolysis pathway comprising blood coagulation proteases L Yang, Y Li, A Bhattacharya, Y Zhang Oncotarget 7 (27), 40919, 2016 | 23 | 2016 |
Dual inhibition of ErbB1 and ErbB2 in cancer by recombinant human prolidase mutant hPEPD-G278D L Yang, Y Li, A Bhattacharya, Y Zhang Oncotarget 7 (27), 42340, 2016 | 18 | 2016 |
Inhibition of ERBB2-overexpressing tumors by recombinant human prolidase and its enzymatically inactive mutant L Yang, Y Li, A Bhattacharya, Y Zhang EBioMedicine 2 (5), 396-405, 2015 | 16 | 2015 |
Anticoagulants inhibit proteolytic clearance of plasma amyloid beta L Yang, A Bhattacharya, Y Li, Y Zhang Oncotarget 9 (5), 5614, 2018 | 12 | 2018 |
Depleting receptor tyrosine kinases EGFR and HER2 overcomes resistance to EGFR inhibitors in colorectal cancer L Yang, A Bhattacharya, Y Li, S Sexton, X Ling, F Li, Y Zhang Journal of Experimental and Clinical Cancer Research 4 (184), 1-19, 2022 | 11 | 2022 |
Verticillin chloroform solvate F Liu, S Wu, Y Chen, L Yang, P Wu Acta Crystallographica Section E: Structure Reports Online 62 (3), o974-o976, 2006 | 9 | 2006 |
Loss of peptidase D binding restores the tumor suppressor functions of oncogenic p53 mutants L Yang, Y Li, A Bhattacharya, Y Zhang Communications Biology 4 (1373), 1-16, 2021 | 3 | 2021 |