Oncolytic viruses in cancer treatment: a review SE Lawler, MC Speranza, CF Cho, EA Chiocca JAMA oncology 3 (6), 841-849, 2017 | 602 | 2017 |
Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles FL Ricklefs, Q Alayo, H Krenzlin, AB Mahmoud, MC Speranza, ... Science advances 4 (3), eaar2766, 2018 | 507 | 2018 |
A radial glia gene marker, fatty acid binding protein 7 (FABP7), is involved in proliferation and invasion of glioblastoma cells A De Rosa, S Pellegatta, M Rossi, P Tunici, L Magnoni, MC Speranza, ... PloS one 7 (12), e52113, 2012 | 139 | 2012 |
Concurrent dexamethasone limits the clinical benefit of immune checkpoint blockade in glioblastoma JB Iorgulescu, PC Gokhale, MC Speranza, BK Eschle, MJ Poitras, ... Clinical Cancer Research 27 (1), 276-287, 2021 | 120 | 2021 |
Arming an oncolytic herpes simplex virus type 1 with a single-chain fragment variable antibody against PD-1 for experimental glioblastoma therapy C Passaro, Q Alayo, I DeLaura, J McNulty, K Grauwet, H Ito, V Bhaskaran, ... Clinical Cancer Research 25 (1), 290-299, 2019 | 111 | 2019 |
NEDD9, a novel target of miR-145, increases the invasiveness of glioblastoma MC Speranza, V Frattini, F Pisati, D Kapetis, P Porrati, M Eoli, S Pellegatta, ... Oncotarget 3 (7), 723, 2012 | 104 | 2012 |
Preclinical investigation of combined gene-mediated cytotoxic immunotherapy and immune checkpoint blockade in glioblastoma MC Speranza, C Passaro, F Ricklefs, K Kasai, SR Klein, H Nakashima, ... Neuro-oncology 20 (2), 225-235, 2018 | 75 | 2018 |
Histone deacetylase 6 inhibition enhances oncolytic viral replication in glioma EAC Hiroshi Nakashima, Johanna K. Kaufmann, Pin-Yi Wang, Tran Nguyen, Maria ... J Clin Invest, 2015 | 71 | 2015 |
TSC2-deficient tumors have evidence of T cell exhaustion and respond to anti–PD-1/anti–CTLA-4 immunotherapy HJ Liu, PH Lizotte, H Du, MC Speranza, HC Lam, S Vaughan, N Alesi, ... JCI insight 3 (8), 2018 | 59 | 2018 |
BKM-120 (Buparlisib): A phosphatidyl-inositol-3 kinase inhibitor with anti-invasive properties in glioblastoma MC Speranza, MO Nowicki, P Behera, CF Cho, EA Chiocca, SE Lawler Scientific reports 6 (1), 20189, 2016 | 45 | 2016 |
Iron overload enhances human mesenchymal stromal cell growth and hampers matrix calcification A Borriello, I Caldarelli, MC Speranza, S Scianguetta, A Tramontano, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (6), 1211-1223, 2016 | 41 | 2016 |
FOXP3, a novel glioblastoma oncosuppressor, affects proliferation and migration V Frattini, F Pisati, MC Speranza, PL Poliani, G Frigé, G Cantini, D Kapetis, ... Oncotarget 3 (10), 1146, 2012 | 36 | 2012 |
Losartan controls immune checkpoint blocker-induced edema and improves survival in glioblastoma mouse models M Datta, S Chatterjee, EM Perez, S Gritsch, S Roberge, M Duquette, ... Proceedings of the National Academy of Sciences 120 (6), e2219199120, 2023 | 26 | 2023 |
Design of a microfluidic chip for magnetic-activated sorting of one-bead-one-compound libraries CF Cho, K Lee, MC Speranza, FC Bononi, MS Viapiano, LG Luyt, ... ACS combinatorial science 18 (6), 271-278, 2016 | 16 | 2016 |
Preclinical mouse models for analysis of the therapeutic potential of engineered oncolytic herpes viruses MC Speranza, K Kasai, SE Lawler ILAR journal 57 (1), 63-72, 2016 | 16 | 2016 |
Histone Deacetylase Inhibitors Increase p27Kip1 by Affecting Its Ubiquitin‐Dependent Degradation through Skp2 Downregulation A Borriello, S Naviglio, D Bencivenga, I Caldarelli, A Tramontano, ... Oxidative Medicine and Cellular Longevity 2016 (1), 2481865, 2016 | 13 | 2016 |
PD-1 blockade activates conventional CD4 T cells and the innate immune response during glioblastoma eradication S Klein, J Ziello, M Speranza, P Gokhale, P Kirschmeier, K Crosby, ... The Journal of Immunology 200 (1_Supplement), 57.9-57.9, 2018 | 9 | 2018 |
Correction: arming an oncolytic herpes simplex virus type 1 with a single-chain fragment variable antibody against PD-1 for experimental glioblastoma therapy C Passaro, Q Alayo, I DeLaura, J McNulty, K Grauwet, H Ito, V Bhaskaran, ... Clinical Cancer Research 26 (3), 758-758, 2020 | 8 | 2020 |
Inhibition of IDO1 with epacadostat enhances anti-tumor efficacy of PD-1 blockade in a syngeneic glioblastoma (GBM) model DA Reardon, PC Gokhale, SR Klein, KL Jones, PT Kirschmeier, ... Cancer Research 77 (13_Supplement), 572-572, 2017 | 6 | 2017 |
Triple checkpoint blockade targeting PD-1, TIM-3, and LAG-3 reinvigorates ovarian cancer-infiltrating T cells by increasing T cell polyfunctionality and effector function JK Kaufmann, B Flynn, K Morse, MC Speranza, J Zhou, S Ramaswamy, ... Cancer Research 79 (13_Supplement), 3242-3242, 2019 | 3 | 2019 |