Thermotolerance requires refolding of aggregated proteins by substrate translocation through the central pore of ClpB J Weibezahn, P Tessarz, C Schlieker, R Zahn, Z Maglica, S Lee, ... Cell 119 (5), 653-665, 2004 | 547 | 2004 |
ClpS, a substrate modulator of the ClpAP machine DA Dougan, BG Reid, AL Horwich, B Bukau Molecular cell 9 (3), 673-683, 2002 | 357 | 2002 |
Adapting the machine: adaptor proteins for Hsp100/Clp and AAA+ proteases J Kirstein, N Molière, DA Dougan, K Turgay Nature Reviews Microbiology 7 (8), 589-599, 2009 | 284 | 2009 |
ClpS is an essential component of the N-end rule pathway in Escherichia coli A Erbse, R Schmidt, T Bornemann, J Schneider-Mergener, A Mogk, ... Nature 439 (7077), 753-756, 2006 | 276 | 2006 |
AAA+ proteins and substrate recognition, it all depends on their partner in crime DA Dougan, A Mogk, K Zeth, K Turgay, B Bukau FEBS letters 529 (1), 6-10, 2002 | 269 | 2002 |
Protein folding and degradation in bacteria:¶ To degrade or not to degrade? That is the question DA Dougan, A Mogk, B Bukau Cellular and Molecular Life Sciences CMLS 59, 1607-1616, 2002 | 194 | 2002 |
MecA, an adaptor protein necessary for ClpC chaperone activity T Schlothauer, A Mogk, DA Dougan, B Bukau, K Turgay Proceedings of the National Academy of Sciences 100 (5), 2306-2311, 2003 | 185 | 2003 |
Adaptor protein controlled oligomerization activates the AAA+ protein ClpC J Kirstein, T Schlothauer, DA Dougan, H Lilie, G Tischendorf, A Mogk, ... The EMBO journal 25 (7), 1481-1491, 2006 | 169 | 2006 |
Structural analysis of the adaptor protein ClpS in complex with the N-terminal domain of ClpA K Zeth, RB Ravelli, K Paal, S Cusack, B Bukau, DA Dougan Nature structural biology 9 (12), 906-911, 2002 | 159 | 2002 |
Insertion and assembly of human tom7 into the preprotein translocase complex of the outer mitochondrial membrane AJ Johnston, J Hoogenraad, DA Dougan, KN Truscott, M Yano, M Mori, ... Journal of Biological Chemistry 277 (44), 42197-42204, 2002 | 154 | 2002 |
Targeted delivery of an ssrA-tagged substrate by the adaptor protein SspB to its cognate AAA+ protein ClpX DA Dougan, E Weber-Ban, B Bukau Molecular cell 12 (2), 373-380, 2003 | 153 | 2003 |
The N-end rule pathway: from recognition by N-recognins, to destruction by AAA+ proteases DA Dougan, D Micevski, KN Truscott Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (1), 83-91, 2012 | 129 | 2012 |
LON is the master protease that protects against protein aggregation in human mitochondria through direct degradation of misfolded proteins A Bezawork-Geleta, EJ Brodie, DA Dougan, KN Truscott Scientific reports 5 (1), 17397, 2015 | 122 | 2015 |
Effects of substitutions in the binding surface of an antibody on antigen affinity. DA Dougan, RL Malby, LC Gruen, AA Kortt, PJ Hudson Protein engineering 11 (1), 65-74, 1998 | 117 | 1998 |
The bacterial N‐end rule pathway: expect the unexpected DA Dougan, KN Truscott, K Zeth Molecular microbiology 76 (3), 545-558, 2010 | 110 | 2010 |
Modification of PATase by L/F‐transferase generates a ClpS‐dependent N‐end rule substrate in Escherichia coli RL Ninnis, SK Spall, GH Talbo, KN Truscott, DA Dougan The EMBO journal 28 (12), 1732-1744, 2009 | 107 | 2009 |
Structural basis of N‐end rule substrate recognition in Escherichia coli by the ClpAP adaptor protein ClpS VJ Schuenemann, SM Kralik, R Albrecht, SK Spall, KN Truscott, ... EMBO reports 10 (5), 508-514, 2009 | 106 | 2009 |
The tyrosine kinase McsB is a regulated adaptor protein for ClpCP J Kirstein, DA Dougan, U Gerth, M Hecker, K Turgay The EMBO Journal 26 (8), 2061-2070, 2007 | 103 | 2007 |
Machines of destruction–AAA+ proteases and the adaptors that control them E Gur, R Ottofueling, DA Dougan Regulated proteolysis in microorganisms, 3-33, 2013 | 65 | 2013 |
Broad yet high substrate specificity: the challenge of AAA+ proteins A Mogk, D Dougan, J Weibezahn, C Schlieker, K Turgay, B Bukau Journal of structural biology 146 (1-2), 90-98, 2004 | 64 | 2004 |