The structural basis of blebbistatin inhibition and specificity for myosin II JS Allingham, R Smith, I Rayment Nature structural & molecular biology 12 (4), 378-379, 2005 | 390 | 2005 |
Actin-targeting natural products: structures, properties and mechanisms of action JS Allingham, VA Klenchin, I Rayment Cellular and Molecular Life Sciences CMLS 63, 2119-2134, 2006 | 235 | 2006 |
An antifreeze protein folds with an interior network of more than 400 semi-clathrate waters T Sun, FH Lin, RL Campbell, JS Allingham, PL Davies Science 343 (6172), 795-798, 2014 | 207 | 2014 |
Trisoxazole macrolide toxins mimic the binding of actin-capping proteins to actin VA Klenchin, JS Allingham, R King, J Tanaka, G Marriott, I Rayment Nature Structural & Molecular Biology 10 (12), 1058-1063, 2003 | 175 | 2003 |
Vik1 modulates microtubule-Kar3 interactions through a motor domain that lacks an active site JS Allingham, LR Sproul, I Rayment, SP Gilbert Cell 128 (6), 1161-1172, 2007 | 107 | 2007 |
Structure of a 1.5-MDa adhesin that binds its Antarctic bacterium to diatoms and ice S Guo, CA Stevens, TDR Vance, LLC Olijve, LA Graham, RL Campbell, ... Science advances 3 (8), e1701440, 2017 | 105 | 2017 |
A structural basis for regulation of actin polymerization by pectenotoxins JS Allingham, CO Miles, I Rayment Journal of molecular biology 371 (4), 959-970, 2007 | 98 | 2007 |
Structures of microfilament destabilizing toxins bound to actin provide insight into toxin design and activity JS Allingham, A Zampella, MV D'Auria, I Rayment Proceedings of the National Academy of Sciences 102 (41), 14527-14532, 2005 | 98 | 2005 |
The RAG1/RAG2 complex constitutes a 3′ flap endonuclease: implications for junctional diversity in V (D) J and transpositional recombination S Santagata, E Besmer, A Villa, F Bozzi, JS Allingham, C Sobacchi, ... Molecular cell 4 (6), 935-947, 1999 | 85 | 1999 |
All three residues of the Tn10 transposase DDE catalytic triad function in divalent metal ion binding JS Allingham, PA Pribil, DB Haniford Journal of molecular biology 289 (5), 1195-1206, 1999 | 63 | 1999 |
Actin-binding cleft closure in myosin II probed by site-directed spin labeling and pulsed EPR JC Klein, AR Burr, B Svensson, DJ Kennedy, J Allingham, MA Titus, ... Proceedings of the National Academy of Sciences 105 (35), 12867-12872, 2008 | 62 | 2008 |
KIF14 binds tightly to microtubules and adopts a rigor-like conformation K Arora, L Talje, AB Asenjo, P Andersen, K Atchia, M Joshi, H Sosa, ... Journal of Molecular Biology 426 (17), 2997-3015, 2014 | 60 | 2014 |
Ternary complex of Kif2A-bound tandem tubulin heterodimers represents a kinesin-13-mediated microtubule depolymerization reaction intermediate D Trofimova, M Paydar, A Zara, L Talje, BH Kwok, JS Allingham Nature communications 9 (1), 2628, 2018 | 59 | 2018 |
The small molecule tool (S)-(−)-blebbistatin: novel insights of relevance to myosin inhibitor design C Lucas-Lopez, JS Allingham, T Lebl, CPAT Lawson, R Brenk, JR Sellers, ... Organic & biomolecular chemistry 6 (12), 2076-2084, 2008 | 50 | 2008 |
Absolute stereochemistry of ulapualide A JS Allingham, J Tanaka, G Marriott, I Rayment Organic Letters 6 (4), 597-599, 2004 | 50 | 2004 |
Loss-of-function mutations in KIF14 cause severe microcephaly and kidney development defects in humans and zebrafish ML Reilly, MF Stokman, V Magry, C Jeanpierre, M Alves, M Paydar, ... Human molecular genetics 28 (5), 778-795, 2019 | 47 | 2019 |
Determinants for hairpin formation in Tn10 transposition JS Allingham, SJ Wardle, DB Haniford The EMBO Journal, 2001 | 41 | 2001 |
Crystal structure of calpain‐3 penta‐EF‐hand (PEF) domain–a homodimerized PEF family member with calcium bound at the fifth EF‐hand SK Partha, R Ravulapalli, JS Allingham, RL Campbell, PL Davies The FEBS journal 281 (14), 3138-3149, 2014 | 34 | 2014 |
Role of Ca2+ in folding the tandem β‐sandwich extender domains of a bacterial ice‐binding adhesin S Guo, CP Garnham, S Karunan Partha, RL Campbell, JS Allingham, ... The FEBS journal 280 (22), 5919-5932, 2013 | 32 | 2013 |
Ste2 receptor-mediated chemotropism of Fusarium graminearum contributes to its pathogenicity against wheat PS Sridhar, D Trofimova, R Subramaniam, D González-Peña Fundora, ... Scientific Reports 10 (1), 10770, 2020 | 30 | 2020 |