A transverse tubule NADPH oxidase activity stimulates calcium release from isolated triads via ryanodine receptor type 1 S-glutathionylation C Hidalgo, G Sánchez, G Barrientos, P Aracena-Parks Journal of Biological Chemistry 281 (36), 26473-26482, 2006 | 205 | 2006 |
Dexmedetomidine preconditioning activates pro-survival kinases and attenuates regional ischemia/reperfusion injury in rat heart M Ibacache, G Sanchez, Z Pedrozo, F Galvez, C Humeres, G Echevarria, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1822 (4), 537-545, 2012 | 170 | 2012 |
Exercise induces early and late myocardial preconditioning in dogs R Domenech, P Macho, H Schwarze, G Sánchez Cardiovascular research 55 (3), 561-566, 2002 | 168 | 2002 |
The signalling pathway of CaMKII-mediated apoptosis and necrosis in the ischemia/reperfusion injury MA Salas, CA Valverde, G Sánchez, M Said, JS Rodriguez, EL Portiansky, ... Journal of molecular and cellular cardiology 48 (6), 1298-1306, 2010 | 144 | 2010 |
S-glutathionylation decreases Mg2+ inhibition and S-nitrosylation enhances Ca2+ activation of RyR1 channels P Aracena, G Sánchez, P Donoso, SL Hamilton, C Hidalgo Journal of Biological Chemistry 278 (44), 42927-42935, 2003 | 140 | 2003 |
Tachycardia increases NADPH oxidase activity and RyR2 S-glutathionylation in ventricular muscle G Sánchez, Z Pedrozo, RJ Domenech, C Hidalgo, P Donoso Journal of molecular and cellular cardiology 39 (6), 982-991, 2005 | 134 | 2005 |
Modulation of cardiac ryanodine receptor activity by ROS and RNS P Donoso, G Sanchez, R Bull, C Hidalgo Front Biosci 16, 553-567, 2011 | 133 | 2011 |
Exercise and tachycardia increase NADPH oxidase and ryanodine receptor-2 activity: possible role in cardioprotection G Sánchez, M Escobar, Z Pedrozo, P Macho, R Domenech, S Härtel, ... Cardiovascular research 77 (2), 380-386, 2008 | 129 | 2008 |
Ischemia enhances activation by Ca2+ and redox modification of ryanodine receptor channels from rat brain cortex R Bull, JP Finkelstein, J Gálvez, G Sánchez, P Donoso, MI Behrens, ... Journal of Neuroscience 28 (38), 9463-9472, 2008 | 107 | 2008 |
Drp1 loss-of-function reduces cardiomyocyte oxygen dependence protecting the heart from ischemia-reperfusion injury R Zepeda, J Kuzmicic, V Parra, R Troncoso, C Pennanen, JA Riquelme, ... Journal of cardiovascular pharmacology 63 (6), 477-487, 2014 | 106 | 2014 |
Ca2+/calmodulin kinase II increases ryanodine binding and Ca2+-induced sarcoplasmic reticulum Ca2+ release kinetics during β-adrenergic stimulation P Ferrero, M Said, G Sánchez, L Vittone, C Valverde, P Donoso, ... Journal of molecular and cellular cardiology 43 (3), 281-291, 2007 | 98 | 2007 |
Calpains and proteasomes mediate degradation of ryanodine receptors in a model of cardiac ischemic reperfusion Z Pedrozo, G Sánchez, N Torrealba, R Valenzuela, C Fernández, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1802 (3), 356-362, 2010 | 97 | 2010 |
Calcium release by ryanodine receptors mediates hydrogen peroxide-induced activation of ERK and CREB phosphorylation in N2a cells and hippocampal neurons U Kemmerling, P Muñoz, M Müller, G Sánchez, ML Aylwin, E Klann, ... Cell calcium 41 (5), 491-502, 2007 | 95 | 2007 |
Tachycardia preconditions infarct size in dogs: role of adenosine and protein kinase C RJ Domenech, P Macho, D Vélez, G Sánchez, X Liu, N Dhalla Circulation 97 (8), 786-794, 1998 | 92 | 1998 |
Dexmedetomidine protects the heart against ischemia-reperfusion injury by an endothelial eNOS/NO dependent mechanism JA Riquelme, F Westermeier, AR Hall, JM Vicencio, Z Pedrozo, ... Pharmacological research 103, 318-327, 2016 | 91 | 2016 |
Effect of tachycardia on myocardial sarcoplasmic reticulum and Ca2+ dynamics: a mechanism for preconditioning? RJ Domenech, G Sánchez, P Donoso, V Parra, P Macho Journal of molecular and cellular cardiology 35 (12), 1429-1437, 2003 | 57 | 2003 |
Redox regulation of calcium release in skeletal and cardiac muscle C Hidalgo, P Aracena, G Sanchez, P Donoso Biological research 35 (2), 183-193, 2002 | 56 | 2002 |
Cardiomyocyte ryanodine receptor degradation by chaperone-mediated autophagy Z Pedrozo, N Torrealba, C Fernández, D Gatica, B Toro, C Quiroga, ... Cardiovascular research 98 (2), 277-285, 2013 | 55 | 2013 |
Aging impairs hippocampal-dependent recognition memory and LTP and prevents the associated RyR up-regulation A Arias-Cavieres, T Adasme, G Sánchez, P Muñoz, C Hidalgo Frontiers in aging neuroscience 9, 111, 2017 | 49 | 2017 |
N-acetylcysteine prevents the spatial memory deficits and the redox-dependent RyR2 decrease displayed by an Alzheimer’s disease rat model J More, N Galusso, P Veloso, L Montecinos, JP Finkelstein, G Sanchez, ... Frontiers in aging neuroscience 10, 399, 2018 | 44 | 2018 |