Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions F De Sousa E Melo, X Wang, M Jansen, E Fessler, A Trinh, ... Nature medicine 19 (5), 614-618, 2013 | 870 | 2013 |
Pan-cancer analysis of the extent and consequences of intratumor heterogeneity N Andor, TA Graham, M Jansen, LC Xia, CA Aktipis, C Petritsch, HP Ji, ... Nature medicine 22 (1), 105-113, 2016 | 790 | 2016 |
British Society of Gastroenterology guidelines on the diagnosis and management of patients at risk of gastric adenocarcinoma M Banks, D Graham, M Jansen, T Gotoda, S Coda, M Di Pietro, N Uedo, ... Gut 68 (9), 1545-1575, 2019 | 496 | 2019 |
Overexpression of S100A4 in pancreatic ductal adenocarcinomas is associated with poor differentiation and DNA hypomethylation C Rosty, T Ueki, P Argani, M Jansen, CJ Yeo, JL Cameron, RH Hruban, ... The American journal of pathology 160 (1), 45-50, 2002 | 314 | 2002 |
STK11/LKB1 Peutz-Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreas N Sato, C Rosty, M Jansen, N Fukushima, T Ueki, CJ Yeo, JL Cameron, ... The American journal of pathology 159 (6), 2017-2022, 2001 | 307 | 2001 |
LKB1 and AMPK family signaling: the intimate link between cell polarity and energy metabolism M Jansen, JP Ten Klooster, GJ Offerhaus, H Clevers Physiological reviews 89 (3), 777-798, 2009 | 260 | 2009 |
Quantification of crypt and stem cell evolution in the normal and neoplastic human colon AM Baker, B Cereser, S Melton, AG Fletcher, M Rodriguez-Justo, ... Cell reports 8 (4), 940-947, 2014 | 234 | 2014 |
Mst4 and Ezrin induce brush borders downstream of the Lkb1/Strad/Mo25 polarization complex JP ten Klooster, M Jansen, J Yuan, V Oorschot, H Begthel, V Di Giacomo, ... Developmental cell 16 (4), 551-562, 2009 | 182 | 2009 |
Practical and robust identification of molecular subtypes in colorectal cancer by immunohistochemistry A Trinh, K Trumpi, F De Sousa E Melo, X Wang, JH De Jong, E Fessler, ... Clinical cancer research 23 (2), 387-398, 2017 | 167 | 2017 |
TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype E Fessler, J Drost, SR van Hooff, JF Linnekamp, X Wang, M Jansen, ... EMBO molecular medicine 8 (7), 745-760, 2016 | 154 | 2016 |
Aberrant methylation of the 5'CpG island of TSLC1 is common in pancreatic ductal adenocarcinoma and is first manifest in high-grade PanINs M Jansen, N Fukushima, C Rosty, K Walter, R Altink, T Heek, R Hruban, ... Cancer biology & therapy 1 (3), 293-296, 2002 | 146 | 2002 |
Evolutionary history of human colitis-associated colorectal cancer AM Baker, W Cross, K Curtius, I Al Bakir, CHR Choi, HL Davis, D Temko, ... Gut 68 (6), 985-995, 2019 | 143 | 2019 |
Mucosal prolapse in the pathogenesis of Peutz-Jeghers polyposis M Jansen, WWJ De Leng, AF Baas, H Myoshi, L Mathus-Vliegen, ... Gut 55 (1), 1-5, 2006 | 141 | 2006 |
Current perspectives on antiangiogenesis strategies in the treatment of malignant gliomas M Jansen, PC de Witt Hamer, AN Witmer, D Troost, CJF van Noorden Brain research reviews 45 (3), 143-163, 2004 | 140 | 2004 |
Long-term follow-up of percutaneous transhepatic therapy (PTT) in patients with definite benign anastomotic strictures after hepaticojejunostomy B Schumacher, T Othman, M Jansen, C Preiss, H Neuhaus Endoscopy 33 (05), 409-415, 2001 | 126 | 2001 |
Gastrointestinal polyposis syndromes LAA Brosens, WA van Hattem, M Jansen, WWJ de Leng, FM Giardiello, ... Current molecular medicine 7 (1), 29-46, 2007 | 122 | 2007 |
Endoscopic tissue sampling–Part 1: upper gastrointestinal and hepatopancreatobiliary tracts. European Society of gastrointestinal endoscopy (ESGE) guideline RE Pouw, M Barret, K Biermann, R Bisschops, L Czakó, KB Gecse, ... Endoscopy 53 (11), 1174-1188, 2021 | 120 | 2021 |
The evolutionary landscape of colorectal tumorigenesis W Cross, M Kovac, V Mustonen, D Temko, H Davis, AM Baker, S Biswas, ... Nature ecology & evolution 2 (10), 1661-1672, 2018 | 116 | 2018 |
Plasma membrane recruitment of dephosphorylated β-catenin upon activation of the Wnt pathway J Hendriksen, M Jansen, CM Brown, H van der Velde, M van Ham, ... Journal of cell science 121 (11), 1793-1802, 2008 | 111 | 2008 |
Undifferentiated sarcomas develop through distinct evolutionary pathways CD Steele, M Tarabichi, D Oukrif, AP Webster, H Ye, M Fittall, P Lombard, ... Cancer Cell 35 (3), 441-456. e8, 2019 | 97 | 2019 |