Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis RG Knodell, KG Ishak, WC Black, TS Chen, R Craig, N Kaplowitz, ... Hepatology 1 (5), 431-435, 1981 | 4731 | 1981 |
Idiosyncratic drug hepatotoxicity N Kaplowitz Nature reviews Drug discovery 4 (6), 489-499, 2005 | 1254 | 2005 |
Case definition and phenotype standardization in drug‐induced liver injury GP Aithal, PB Watkins, RJ Andrade, D Larrey, M Molokhia, H Takikawa, ... Clinical Pharmacology & Therapeutics 89 (6), 806-815, 2011 | 1162 | 2011 |
EASL clinical practice guidelines: drug-induced liver injury RJ Andrade, GP Aithal, ES Björnsson, N Kaplowitz, GA Kullak-Ublick, ... Journal of hepatology 70 (6), 1222-1261, 2019 | 1146* | 2019 |
Features and outcomes of 899 patients with drug-induced liver injury: the DILIN prospective study N Chalasani, HL Bonkovsky, R Fontana, W Lee, A Stolz, J Talwalkar, ... Gastroenterology 148 (7), 1340-1352. e7, 2015 | 926 | 2015 |
The regulation of hepatic glutathione N Kaplowitz, TY Aw, M Ookhtens Annual review of pharmacology and toxicology 25 (1), 715-744, 1985 | 833 | 1985 |
Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial PB Watkins, N Kaplowitz, JT Slattery, CR Colonese, SV Colucci, ... Jama 296 (1), 87-93, 2006 | 829 | 2006 |
Cell death and cell death responses in liver disease: mechanisms and clinical relevance T Luedde, N Kaplowitz, RF Schwabe Gastroenterology 147 (4), 765-783. e4, 2014 | 793 | 2014 |
Glutathione metabolism and its role in hepatotoxicity LD DeLeve, N Kaplowitz Pharmacology & therapeutics 52 (3), 287-305, 1991 | 668 | 1991 |
Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice C Ji, N Kaplowitz Gastroenterology 124 (5), 1488-1499, 2003 | 650 | 2003 |
Drug-induced liver injury N Kaplowitz Clinical infectious diseases 38 (Supplement_2), S44-S48, 2004 | 633 | 2004 |
Textbook of gastroenterology T Yamada, DH Alpers, AN Kalloo, N Kaplowitz, C Owyang, DW Powell John Wiley & Sons, 2011 | 585 | 2011 |
Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injury N Hanawa, M Shinohara, B Saberi, WA Gaarde, D Han, N Kaplowitz Journal of Biological Chemistry 283 (20), 13565-13577, 2008 | 578 | 2008 |
c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity BK Gunawan, ZX Liu, D Han, N Hanawa, WA Gaarde, N Kaplowitz Gastroenterology 131 (1), 165-178, 2006 | 537 | 2006 |
Mechanisms of liver cell injury N Kaplowitz Journal of hepatology 32, 39-47, 2000 | 529 | 2000 |
GSH transport in mitochondria: defense against TNF-induced oxidative stress and alcohol-induced defect JC Fernandez-Checa, N Kaplowitz, C Garcia-Ruiz, A Colell, M Miranda, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 273 (1 …, 1997 | 498 | 1997 |
Drug-induced liver disorders: implications for drug development and regulation N Kaplowitz Drug safety 24, 483-490, 2001 | 489 | 2001 |
Serum alanine aminotransferase in skeletal muscle diseases RA Nathwani, S Pais, TB Reynolds, N Kaplowitz Hepatology 41 (2), 380-382, 2005 | 477 | 2005 |
Role of oxidative stress generated from the mitochondrial electron transport chain and mitochondrial glutathione status in loss of mitochondrial function and activation of … C García-Ruiz, A Colell, A Morales, N Kaplowitz, JC Fernández-Checa Molecular pharmacology 48 (5), 825-834, 1995 | 441 | 1995 |
Drug-induced liver injury G Abboud, N Kaplowitz Drug safety 30, 277-294, 2007 | 439 | 2007 |