Pyrene-functionalized oligonucleotides and locked nucleic acids (LNAs): Tools for fundamental research, diagnostics, and nanotechnology ME Østergaard, PJ Hrdlicka Chemical Society Reviews 40 (12), 5771-5788, 2011 | 267 | 2011 |
Multilabeled pyrene-functionalized 2 ‘-amino-LNA probes for nucleic acid detection in homogeneous fluorescence assays PJ Hrdlicka, BR Babu, MD Sørensen, N Harrit, J Wengel Journal of the American Chemical Society 127 (38), 13293-13299, 2005 | 147 | 2005 |
C2′-pyrene-functionalized triazole-linked DNA: Universal DNA/RNA hybridization probes SP Sau, PJ Hrdlicka The Journal of organic chemistry 77 (1), 5-16, 2012 | 70 | 2012 |
Synthesis and hybridization studies of 2 ‘-amino-α-L-LNA and tetracyclic “Locked LNA” TS Kumar, AS Madsen, J Wengel, PJ Hrdlicka The Journal of Organic Chemistry 71 (11), 4188-4201, 2006 | 61 | 2006 |
DNA detection on lateral flow test strips: enhanced signal sensitivity using LNA-conjugated gold nanoparticles D áEric Aston, A áLarry Branen Chemical communications 48 (62), 7714-7716, 2012 | 55 | 2012 |
Interstrand communication between 2′-N-(pyren-1-yl) methyl-2′-amino-LNA monomers in nucleic acid duplexes: directional control and signalling of full complementarity PJ Hrdlicka, BR Babu, MD Sørensen, J Wengel Chemical communications, 1478-1479, 2004 | 55 | 2004 |
2′‐N‐(Pyren‐1‐yl)acetyl‐2′‐Amino‐α‐L‐LNA: Synthesis and Detection of Single Nucleotide Mismatches in DNA and RNA Targets TS Kumar, J Wengel, PJ Hrdlicka ChemBioChem 8 (10), 1122-1125, 2007 | 52 | 2007 |
Invader LNA: efficient targeting of short double stranded DNA SP Sau, TS Kumar, PJ Hrdlicka Organic & biomolecular chemistry 8 (9), 2028-2036, 2010 | 51 | 2010 |
Functionalized 2′-amino-α-L-LNA: directed positioning of intercalators for DNA targeting TS Kumar, AS Madsen, ME Østergaard, SP Sau, J Wengel, PJ Hrdlicka The Journal of organic chemistry 74 (3), 1070-1081, 2009 | 51 | 2009 |
Glowing locked nucleic acids: brightly fluorescent probes for detection of nucleic acids in cells ME Østergaard, P Cheguru, MR Papasani, RA Hill, PJ Hrdlicka Journal of the American Chemical Society 132 (40), 14221-14228, 2010 | 50 | 2010 |
Sensitive SNP Dual‐Probe Assays Based on Pyrene‐Functionalized 2′‐Amino‐LNA: Lessons To Be Learned T Umemoto, PJ Hrdlicka, BR Babu, J Wengel ChemBioChem 8 (18), 2240-2248, 2007 | 48 | 2007 |
Gold-peptide nanoconjugate cellular uptake is modulated by serum proteins G Wang, MR Papasani, P Cheguru, PJ Hrdlicka, RA Hill Nanomedicine: Nanotechnology, Biology and Medicine, 2011 | 42 | 2011 |
Silica nanosprings coated with noble metal nanoparticles: Highly active SERS substrates VVR Sai, D Gangadean, I Niraula, JMF Jabal, G Corti, DN McIlroy, ... The Journal of Physical Chemistry C 115 (2), 453-459, 2011 | 41 | 2011 |
High-affinity DNA targeting using readily accessible mimics of N2′-functionalized 2′-Amino-α-L-LNA S Karmakar, BA Anderson, RL Rathje, S Andersen, TB Jensen, P Nielsen, ... The Journal of organic chemistry 76 (17), 7119-7131, 2011 | 40 | 2011 |
Nucleic acid structural engineering using pyrene-functionalized 2′-amino-α-L-LNA monomers and abasic sites TS Kumar, AS Madsen, ME Østergaard, J Wengel, PJ Hrdlicka The Journal of Organic Chemistry 73 (18), 7060-7066, 2008 | 38 | 2008 |
Identification and characterization of second-generation invader locked nucleic acids (LNAs) for mixed-sequence recognition of double-stranded DNA SP Sau, AS Madsen, P Podbevsek, NK Andersen, TS Kumar, S Andersen, ... The Journal of organic chemistry 78 (19), 9560-9570, 2013 | 37 | 2013 |
C5‐Functionalized DNA, LNA, and α‐L‐LNA: Positional Control of Polarity‐Sensitive Fluorophores Leads to Improved SNP‐Typing ME Østergaard, P Kumar, B Baral, DC Guenther, BA Anderson, ... Chemistry–A European Journal 17 (11), 3157-3165, 2011 | 37 | 2011 |
Next-generation bis-locked nucleic acids with stacking linker and 2′-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes S Geny, PMD Moreno, T Krzywkowski, O Gissberg, NK Andersen, AJ Isse, ... Nucleic acids research 44 (5), 2007-2019, 2016 | 34 | 2016 |
Pyrene-functionalized triazole-linked 2′-deoxyuridines—probes for discrimination of single nucleotide polymorphisms (SNPs) ME Østergaard, DC Guenther, P Kumar, B Baral, L Deobald, ... Chemical communications 46 (27), 4929-4931, 2010 | 34 | 2010 |
Synthesis and biophysical properties of C5-functionalized LNA (locked nucleic acid) P Kumar, ME Østergaard, B Baral, BA Anderson, DC Guenther, M Kaura, ... The Journal of Organic Chemistry 79 (11), 5047-5061, 2014 | 33 | 2014 |