SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity L Zhang, CB Jackson, H Mou, A Ojha, H Peng, BD Quinlan, ... Nature communications 11 (1), 6013, 2020 | 1105 | 2020 |
Receptor affinity and extracellular domain modifications affect tumor recognition by ROR1-specific chimeric antigen receptor T cells M Hudecek, MT Lupo-Stanghellini, PL Kosasih, D Sommermeyer, ... Clinical cancer research 19 (12), 3153-3164, 2013 | 665 | 2013 |
Humanization of murine antibody CF Barbas III, C Rader US Patent 7,087,409, 2006 | 586 | 2006 |
The Nonsignaling Extracellular Spacer Domain of Chimeric Antigen Receptors Is Decisive for In Vivo Antitumor Activity M Hudecek, D Sommermeyer, PL Kosasih, A Silva-Benedict, L Liu, ... Cancer immunology research 3 (2), 125-135, 2015 | 577 | 2015 |
Phage display of combinatorial antibody libraries C Rader, CF Barbas III Current opinion in biotechnology 8 (4), 503-508, 1997 | 356 | 1997 |
The B-cell tumor–associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor M Hudecek, TM Schmitt, S Baskar, MT Lupo-Stanghellini, T Nishida, ... Blood, The Journal of the American Society of Hematology 116 (22), 4532-4541, 2010 | 340 | 2010 |
Unique cell surface expression of receptor tyrosine kinase ROR1 in human B-cell chronic lymphocytic leukemia S Baskar, KY Kwong, T Hofer, JM Levy, MG Kennedy, E Lee, LM Staudt, ... Clinical Cancer Research 14 (2), 396-404, 2008 | 322 | 2008 |
The Nogo-66 receptor homolog NgR2 is a sialic acid-dependent receptor selective for myelin-associated glycoprotein K Venkatesh, O Chivatakarn, H Lee, PS Joshi, DB Kantor, BA Newman, ... Journal of Neuroscience 25 (4), 808-822, 2005 | 308 | 2005 |
A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease D Bagnara, MS Kaufman, C Calissano, S Marsilio, PEM Patten, R Simone, ... Blood, The Journal of the American Society of Hematology 117 (20), 5463-5472, 2011 | 305 | 2011 |
Methods for the generation of chicken monoclonal antibody fragments by phage display J Andris-Widhopf, C Rader, P Steinberger, R Fuller, CF Barbas Iii Journal of immunological methods 242 (1-2), 159-181, 2000 | 298 | 2000 |
A phage display approach for rapid antibody humanization: designed combinatorial V gene libraries C Rader, DA Cheresh, CF Barbas III Proceedings of the National Academy of Sciences 95 (15), 8910-8915, 1998 | 289 | 1998 |
Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals T Derfuss, K Parikh, S Velhin, M Braun, E Mathey, M Krumbholz, ... Proceedings of the National Academy of Sciences 106 (20), 8302-8307, 2009 | 282 | 2009 |
Logic-gated ROR1 chimeric antigen receptor expression rescues T cell-mediated toxicity to normal tissues and enables selective tumor targeting S Srivastava, AI Salter, D Liggitt, S Yechan-Gunja, M Sarvothama, ... Cancer cell 35 (3), 489-503. e8, 2019 | 268 | 2019 |
Immunogenic chemotherapy enhances recruitment of CAR-T cells to lung tumors and improves antitumor efficacy when combined with checkpoint blockade S Srivastava, SN Furlan, CA Jaeger-Ruckstuhl, M Sarvothama, C Berger, ... Cancer cell 39 (2), 193-208. e10, 2021 | 222 | 2021 |
Safety of targeting ROR1 in primates with chimeric antigen receptor–modified T cells C Berger, D Sommermeyer, M Hudecek, M Berger, A Balakrishnan, ... Cancer immunology research 3 (2), 206-216, 2015 | 194 | 2015 |
Rabbit immune repertoires as sources for therapeutic monoclonal antibodies: the impact of kappa allotype-correlated variation in cysteine content on antibody libraries selected … M Popkov, RG Mage, CB Alexander, S Thundivalappil, CF Barbas III, ... Journal of molecular biology 325 (2), 325-335, 2003 | 171 | 2003 |
The rabbit antibody repertoire as a novel source for the generation of therapeutic human antibodies C Rader, G Ritter, S Nathan, M Elia, I Gout, AA Jungbluth, LS Cohen, ... Journal of Biological Chemistry 275 (18), 13668-13676, 2000 | 168 | 2000 |
Multiple event activation of a generic prodrug trigger by antibody catalysis D Shabat, C Rader, B List, RA Lerner, CF Barbas III Proceedings of the National Academy of Sciences 96 (12), 6925-6930, 1999 | 160 | 1999 |
Clinical development of a poly (2-oxazoline)(POZ) polymer therapeutic for the treatment of Parkinson’s disease–Proof of concept of POZ as a versatile polymer platform for drug … RW Moreadith, TX Viegas, MD Bentley, JM Harris, Z Fang, K Yoon, ... European Polymer Journal 88, 524-552, 2017 | 159 | 2017 |
Implications of the HIV-1 Rev dimer structure at 3.2 Å resolution for multimeric binding to the Rev response element MA DiMattia, NR Watts, SJ Stahl, C Rader, PT Wingfield, DI Stuart, ... Proceedings of the National Academy of Sciences 107 (13), 5810-5814, 2010 | 151 | 2010 |