2-Phenylaminonaphthoquinones and related compounds: Synthesis, trypanocidal and cytotoxic activities I Sieveking, P Thomas, JC Estévez, N Quiñones, MA Cuéllar, J Villena, ... Bioorganic & medicinal chemistry 22 (17), 4609-4620, 2014 | 86 | 2014 |
Synthesis, biological evaluation, and molecular simulation of chalcones and aurones as selective MAO‐B inhibitors N Morales‐Camilo, CO Salas, C Sanhueza, C Espinosa‐Bustos, ... Chemical biology & drug design 85 (6), 685-695, 2015 | 67 | 2015 |
Synthesis and pharmacophore modelling of 2, 6, 9-trisubstituted purine derivatives and their potential role as apoptosis-inducing agents in cancer cell lines J Calderón-Arancibia, C Espinosa-Bustos, Á Cañete-Molina, RA Tapia, ... Molecules 20 (4), 6808-6826, 2015 | 46 | 2015 |
New aryloxy-quinone derivatives as potential anti-Chagasic agents: synthesis, trypanosomicidal activity, electrochemical properties, pharmacophore elucidation and 3D-QSAR analysis K Vázquez, C Espinosa-Bustos, J Soto-Delgado, RA Tapia, J Varela, ... RSC advances 5 (80), 65153-65166, 2015 | 38 | 2015 |
State of the art of Smo antagonists for cancer therapy: Advances in the target receptor and new ligand structures C Espinosa-Bustos, J Mella, J Soto-Delgado, CO Salas Future Medicinal Chemistry 11 (6), 617-638, 2019 | 28 | 2019 |
Fluorescence properties of aurone derivatives: an experimental and theoretical study with some preliminary biological applications C Espinosa-Bustos, D Cortés-Arriagada, MA Soto-Arriaza, ... Photochemical & Photobiological Sciences 16, 1268-1276, 2017 | 25 | 2017 |
Enrofloxacin behavior in presence of soil extracted organic matter: an electrochemical approach M Antilén, C Valencia, E Peralta, C Canales, C Espinosa-Bustos, ... Electrochimica Acta 244, 104-111, 2017 | 25 | 2017 |
Design, synthesis, binding and docking-based 3D-QSAR studies of 2-pyridylbenzimidazoles—A new family of high affinity CB1 cannabinoid ligands JA Mella-Raipán, CF Lagos, G Recabarren-Gajardo, C Espinosa-Bustos, ... Molecules 18 (4), 3972-4001, 2013 | 23 | 2013 |
New 2, 6, 9-trisubstituted purine derivatives as Bcr-Abl and Btk inhibitors and as promising agents against leukemia J Bertrand, H Dostálová, V Krystof, R Jorda, A Castro, J Mella, ... Bioorganic Chemistry 94, 103361, 2020 | 20 | 2020 |
Synthesis and biological characterization of new aryloxyindole-4, 9-diones as potent trypanosomicidal agents RA Tapia, CO Salas, K Vázquez, C Espinosa-Bustos, J Soto-Delgado, ... Bioorganic & medicinal chemistry letters 24 (16), 3919-3922, 2014 | 20 | 2014 |
New aryloxy‐quinone derivatives with promising activity on Trypanosoma cruzi C Espinosa‐Bustos, K Vázquez, J Varela, H Cerecetto, M Paulino, ... Archiv der Pharmazie 353 (1), 1900213, 2020 | 17 | 2020 |
Promising 2, 6, 9-trisubstituted purine derivatives for anticancer compounds: Synthesis, 3D-QSAR, and preliminary biological assays C O. Salas, AM Zarate, V Kryštof, J Mella, M Faundez, J Brea, MI Loza, ... International journal of molecular sciences 21 (1), 161, 2019 | 17 | 2019 |
Nature-inspired pyrrolo [2, 3-d] pyrimidines targeting the histamine H3 receptor A Frank, F Meza-Arriagada, CO Salas, C Espinosa-Bustos, H Stark Bioorganic & Medicinal Chemistry 27 (14), 3194-3200, 2019 | 16 | 2019 |
A one-pot approach to 2-(N-substituted amino)-1, 4-naphthoquinones with use of nitro compounds and 1, 4-naphthoquinones in water XL Chen, Y Dong, S He, R Zhang, H Zhang, L Tang, XM Zhang, JY Wang Synlett 30 (05), 615-619, 2019 | 16 | 2019 |
A new smoothened antagonist bearing the purine scaffold shows antitumour activity in vitro and in vivo AM Zárate, C Espinosa-Bustos, S Guerrero, A Fierro, F Oyarzún-Ampuero, ... International journal of molecular sciences 22 (16), 8372, 2021 | 14 | 2021 |
New imidoyl-indazole platinum (II) complexes as potential anticancer agents: Synthesis, evaluation of cytotoxicity, cell death and experimental-theoretical DNA interaction studies AR Cabrera, C Espinosa-Bustos, M Faúndez, J Meléndez, P Jaque, ... Journal of Inorganic Biochemistry 174, 90-101, 2017 | 14 | 2017 |
Microwave-assisted synthesis and regioisomeric structural elucidation of novel benzimidazo [1, 2d][1, 4] benzodiazepinone derivatives D Pessoa, C Espinosa Bustos, JA Mella Raipán, J Canales Pacheco, ... ARKAT USA INC, 2009 | 14 | 2009 |
Design, synthesis, biological evaluation and binding mode modeling of benzimidazole derivatives targeting the cannabinoid receptor type 1 C Espinosa‐Bustos, CF Lagos, J Romero‐Parra, AM Zárate, ... Archiv der Pharmazie 348 (2), 81-88, 2015 | 10 | 2015 |
New Amino Naphthoquinone Derivatives as Anti-Trypanosoma cruzi Agents Targeting Trypanothione Reductase C Espinosa-Bustos, M Ortiz Pérez, A Gonzalez-Gonzalez, AM Zarate, ... Pharmaceutics 14 (6), 1121, 2022 | 9 | 2022 |
Hepatoprotective species from the Chilean medicinal flora: Junellia spathulata (Verbenaceae) R Bridi, GL von Poser, M Gómez, ME Andia, JE Oyarzún, P Núñez, ... Journal of Ethnopharmacology 267, 113543, 2021 | 9 | 2021 |