| The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1α L Zhong, A D'Urso, D Toiber, C Sebastian, RE Henry, DD Vadysirisack, ... Cell 140 (2), 280-293, 2010 | 1133 | 2010 |
| Transcriptional regulation by hypoxia inducible factors VL Dengler, MD Galbraith, JM Espinosa Critical reviews in biochemistry and molecular biology 49 (1), 1-15, 2014 | 875 | 2014 |
| Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment JM Espinosa, BM Emerson Molecular cell 8 (1), 57-69, 2001 | 562 | 2001 |
| Mechanisms of transcriptional regulation by p53 KD Sullivan, MD Galbraith, Z Andrysik, JM Espinosa Cell Death & Differentiation 25 (1), 133-143, 2018 | 462 | 2018 |
| CDK8 is a positive regulator of transcriptional elongation within the serum response network AJ Donner, CC Ebmeier, DJ Taatjes, JM Espinosa Nature structural & molecular biology 17 (2), 194-201, 2010 | 420 | 2010 |
| RNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes K Glover-Cutter, S Kim, J Espinosa, DL Bentley Nature structural & molecular biology 15 (1), 71-78, 2008 | 402 | 2008 |
| HIF1A employs CDK8-mediator to stimulate RNAPII elongation in response to hypoxia MD Galbraith, MA Allen, CL Bensard, X Wang, MK Schwinn, B Qin, ... Cell 153 (6), 1327-1339, 2013 | 382 | 2013 |
| Development of a definition of postacute sequelae of SARS-CoV-2 infection T Thaweethai, SE Jolley, EW Karlson, EB Levitan, B Levy, GA McComsey, ... Jama 329 (22), 1934-1946, 2023 | 379 | 2023 |
| p53 functions through stress-and promoter-specific recruitment of transcription initiation components before and after DNA damage JM Espinosa, RE Verdun, BM Emerson Molecular cell 12 (4), 1015-1027, 2003 | 329 | 2003 |
| CDK8 is a stimulus-specific positive coregulator of p53 target genes AJ Donner, S Szostek, JM Hoover, JM Espinosa Molecular cell 27 (1), 121-133, 2007 | 322 | 2007 |
| Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program NP Gomes, G Bjerke, B Llorente, SA Szostek, BM Emerson, JM Espinosa Genes & development 20 (5), 601-612, 2006 | 300 | 2006 |
| Trisomy 21 consistently activates the interferon response KD Sullivan, HC Lewis, AA Hill, A Pandey, LP Jackson, JM Cabral, ... Elife 5, e16220, 2016 | 274 | 2016 |
| Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms MA Allen, Z Andrysik, VL Dengler, HS Mellert, A Guarnieri, JA Freeman, ... Elife 3, e02200, 2014 | 272 | 2014 |
| CDK8: a positive regulator of transcription MD Galbraith, AJ Donner, JM Espinosa Transcription 1 (1), 4-12, 2010 | 263 | 2010 |
| The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator MT Knuesel, KD Meyer, AJ Donner, JM Espinosa, DJ Taatjes Molecular and cellular biology, 2009 | 261 | 2009 |
| Autophagy inhibition mediates apoptosis sensitization in cancer therapy by relieving FOXO3a turnover BE Fitzwalter, CG Towers, KD Sullivan, Z Andrysik, M Hoh, M Ludwig, ... Developmental cell 44 (5), 555-565. e3, 2018 | 190 | 2018 |
| Trisomy 21 causes changes in the circulating proteome indicative of chronic autoinflammation KD Sullivan, D Evans, A Pandey, TH Hraha, KP Smith, N Markham, ... Scientific reports 7 (1), 14818, 2017 | 183 | 2017 |
| Identification of a core TP53 transcriptional program with highly distributed tumor suppressive activity Z Andrysik, MD Galbraith, AL Guarnieri, S Zaccara, KD Sullivan, A Pandey, ... Genome research 27 (10), 1645-1657, 2017 | 146 | 2017 |
| Down syndrome and COVID-19: a perfect storm? JM Espinosa Cell Reports Medicine 1 (2), 2020 | 136 | 2020 |
| Mechanisms of regulatory diversity within the p53 transcriptional network JM Espinosa Oncogene 27 (29), 4013-4023, 2008 | 136 | 2008 |
