Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice PF McKay, K Hu, AK Blakney, K Samnuan, JC Brown, R Penn, J Zhou, ... Nature communications 11 (1), 3523, 2020 | 427 | 2020 |
Cutting edge: identification of the 2B4 molecule as a counter-receptor for CD48 Y Latchman, PF McKay, H Reiser The Journal of Immunology 161 (11), 5809-5812, 1998 | 233 | 1998 |
Inside out: optimization of lipid nanoparticle formulations for exterior complexation and in vivo delivery of saRNA AK Blakney, PF McKay, BI Yus, Y Aldon, RJ Shattock Gene therapy 26 (9), 363-372, 2019 | 184 | 2019 |
Recruitment and expansion of dendritic cells in vivo potentiate the immunogenicity of plasmid DNA vaccines SM Sumida, PF McKay, DM Truitt, MG Kishko, JC Arthur, MS Seaman, ... The Journal of clinical investigation 114 (9), 1334-1342, 2004 | 157 | 2004 |
Plasmid chemokines and colony-stimulating factors enhance the immunogenicity of DNA priming-viral vector boosting human immunodeficiency virus type 1 vaccines DH Barouch, PF McKay, SM Sumida, S Santra, SS Jackson, DA Gorgone, ... Journal of virology 77 (16), 8729-8735, 2003 | 148 | 2003 |
Heterologous vaccination regimens with self-amplifying RNA and adenoviral COVID vaccines induce robust immune responses in mice AJ Spencer, PF McKay, S Belij-Rammerstorfer, M Ulaszewska, CD Bissett, ... Nature communications 12 (1), 2893, 2021 | 132 | 2021 |
Big is beautiful: enhanced saRNA delivery and immunogenicity by a higher molecular weight, bioreducible, cationic polymer AK Blakney, Y Zhu, PF McKay, CR Bouton, J Yeow, J Tang, K Hu, ... ACS nano 14 (5), 5711-5727, 2020 | 131 | 2020 |
Development, application and validation of a Taqman real-time RT-PCR assay for the detection of infectious salmon anaemia virus (ISAV) in Atlantic salmon (Salmo salar). M Snow, P McKay, AJ McBeath, J Black, F Doig, R Kerr, CO Cunningham, ... Developments in biologicals 126, 133-45; discussion 325, 2006 | 130 | 2006 |
Safety and immunogenicity of a self-amplifying RNA vaccine against COVID-19: COVAC1, a phase I, dose-ranging trial KM Pollock, HM Cheeseman, AJ Szubert, V Libri, M Boffito, D Owen, ... EClinicalMedicine 44, 2022 | 105 | 2022 |
Advances in HIV-1 vaccine development Y Gao, PF McKay, JFS Mann Viruses 10 (4), 167, 2018 | 92 | 2018 |
Increased transmission of SARS-CoV-2 lineage B. 1.1. 7 (VOC 2020212/01) is not accounted for by a replicative advantage in primary airway cells or antibody escape JC Brown, DH Goldhill, J Zhou, TP Peacock, R Frise, N Goonawardane, ... BioRxiv, 2021.02. 24.432576, 2021 | 91 | 2021 |
Neutrophils enable local and non‐invasive liposome delivery to inflamed skeletal muscle and ischemic heart J Che, A Najer, AK Blakney, PF McKay, M Bellahcene, CW Winter, ... Advanced Materials 32 (48), 2003598, 2020 | 89 | 2020 |
Microneedle mediated intradermal delivery of adjuvanted recombinant HIV-1 CN54gp140 effectively primes mucosal boost inoculations A Pattani, PF McKay, MJ Garland, RM Curran, K Migalska, CM Cassidy, ... Journal of controlled release 162 (3), 529-537, 2012 | 88 | 2012 |
Recruitment of different subsets of antigen‐presenting cells selectively modulates DNA vaccine‐elicited CD4+ and CD8+ T lymphocyte responses PF McKay, DH Barouch, S Santra, SM Sumida, SS Jackson, DA Gorgone, ... European journal of immunology 34 (4), 1011-1020, 2004 | 87 | 2004 |
One size does not fit all: the effect of chain length and charge density of poly (ethylene imine) based copolymers on delivery of pDNA, mRNA, and RepRNA polyplexes AK Blakney, G Yilmaz, PF McKay, CR Becer, RJ Shattock Biomacromolecules 19 (7), 2870-2879, 2018 | 80 | 2018 |
Polymeric and lipid nanoparticles for delivery of self-amplifying RNA vaccines AK Blakney, PF McKay, K Hu, K Samnuan, N Jain, A Brown, A Thomas, ... Journal of controlled release 338, 201-210, 2021 | 73 | 2021 |
Rational design of DNA-expressed stabilized native-like HIV-1 envelope trimers Y Aldon, PF McKay, J Allen, G Ozorowski, RF Lévai, M Tolazzi, P Rogers, ... Cell reports 24 (12), 3324-3338. e5, 2018 | 60 | 2018 |
Elicitation of simian immunodeficiency virus-specific cytotoxic T lymphocytes in mucosal compartments of rhesus monkeys by systemic vaccination J Baig, DB Levy, PF McKay, JE Schmitz, S Santra, RA Subbramanian, ... Journal of Virology 76 (22), 11484-11490, 2002 | 60 | 2002 |
Chlamydia trachomatis: Cell biology, immunology and vaccination SM Murray, PF McKay Vaccine 39 (22), 2965-2975, 2021 | 58 | 2021 |
Mutations that adapt SARS-CoV-2 to mink or ferret do not increase fitness in the human airway J Zhou, TP Peacock, JC Brown, DH Goldhill, AME Elrefaey, ... Cell Reports 38 (6), 2022 | 56 | 2022 |